“borderline significant”

However, in the safety set, a post hoc analysis revealed a borderline significant estimated risk difference of 6.8% (95% CI, 0.2%–13%), with a lower risk of withdrawal in the IN group.

Potential confounders were added to the multivariable models if they had significant or borderline significant associations with the outcome variable in the univariable models.

[ 16 , 17 ] Here we evaluated if diabetes would be associated with higher odds of death, but we found the opposite: Diabetes was protective in any age group, and borderline significant among OA (not shown), as reported in Brazil among adults older than 60 years of age.

At the fifth monitoring event at 23 weeks, the global Fisher test indicated a borderline significant influence of treatment, however after Bonferroni corrections on p -values from the pairwise tests, none were significant (Table 1 ).

In addition to point and interval estimation of SU and psychiatric disorder main effects, we also present estimates of joint effects (e.g., having both SU disorder and psychiatric disease diagnosis versus neither diagnosis) given evidence of borderline significant interaction between these two covariates and given the inherent value in directly measuring and presenting estimates of resource use in categories of joint comorbidities.

For mortality, we observe borderline significant risk for males.

Significant heritability was found for the BA44 and BA45 gray matter volumes while BA22 was borderline significant.

A borderline significant result was also observed for higher DHEA levels (Figure 2k ).

Borderline significant correlation was seen in urban girls and BMI (Table 2 ).

There was a borderline significant negative association with previous hormonal treatment.

Birth weight displayed borderline significant relationships with HDL-C and Apo A1, independently of life course exposures and health behavior.

Patients with high cGAS-STING score showed longer OS and PFS, the association for DSS was borderline significant (Fig. 1 b).

Interestingly, when stratifying the data by delivery mode the correlation between PRA and AFCE in the vaginal delivery group was borderline significant in model 5 with a p-value of 0.05.

found that although BCG does not change the proportion of natural killer (NK) cell subsets, it enhances the production of pro-inflammatory cytokines, such as IL-1B, after stimulation with unrelated bacteria [ 36 ], whereas a randomised controlled trial found a borderline significant increasing effect for monocytes [ 12 ].

There were borderline significant differences in the number of patients considered to have died of infections caused by strains of Enterobacteriaceae family or Pseudomonas genus between the early and the late autopsy groups (15/214 [7.0%] vs. 10/68 [14.7%] (p = 0.0518).

Other areas where we feel we have demonstrated appropriate judgement of significance is the inclusion of maternal age in our multivariate model based on our a priori hypothesis, and presentation of other ‘borderline significant’ outcomes, for example the inclusion of hypertension as a risk factor for admission (aOR 3.63, 95% CI 0.99 – 13.30).

On multivariate analysis, high tumour grade was borderline significant with a p-value of 0.051 (Table 6 ).

Significantly lower proportions of men in the Glasgow/Edinburgh survey reported ≥ 10 sexual or AI partners in the previous 12 months, but the difference in the proportions reporting any UAI between the surveys was borderline significant.

However, in the male subgroup analysis, this determinant was only borderline significant.

In the mid (more than 5 cm to 10 cm) rectal cancer group, however, a borderline significant (odds ratio 1.20, 95 per cent c.i. 1.01 to 1.43) higher rate of sphincter preservation was seen in the low-volume surgery group.

As shown in Figure 3 , odds ratios for factors associated with any CKD were virtually identical using iGFR and eGFR, except that current use of tenofovir was significant using iGFR and only borderline significant using eGFR.

Even though the variables risk classification and biochemical failure were not found to be independently associated with OS in the multiple regression analysis, differences in the curves were statistically significant (or borderline significant for biochemical failure) in the univariate logic of the Kaplan-Meier and log-rank test analyses.

Hence, a unit increase in the log-z-score was associated with 19% lower mortality below the median while it was associated with 94% (borderline significant) higher mortality above the median.

Principal components C1–C4 to control for population stratification were added to the model as well as target INR which although only borderline significant, can influence target dose, as well as CYP2C9/VKORC1 metabolizer phenotypes, which are well-established predictors of warfarin dose requirements (Supplementary File 2 , Table 2 ).

Similarly, a cohort study reported a borderline significant association between dietary lutein intake and HPV persistence [ 46 ].