More social jetlag was associated with smoking and better self-rated mental health (all three questionnaires), with borderline significant associations with headaches (p = 0.043) and the absence of palpitations (p = 0.018), but none of the other anthropometric/biomedical measures.
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In contrast, the CAF + SS condition yielded only a borderline significant difference compared to CON ( p = 0.043), with a moderate effect size (ES = 0.54).
We also found a borderline significant association between the C-allele of TMEM154 -rs6813195 and a lower insulinogenic index again both in the analysis with (n = 5,181, β = -0.032, p = 0.043) and without adjustments for BMI (n = 5,182, β = -0.031, p = 0.052) in Inter99.
Moreover, a borderline significant expression level was observed for only one target gene, namely BRCA2 ( p = 4.32 × 10 –2 and adjusted p -value = 5.82 × 10 –2 ).
Differences in ONL thinning rate were borderline significant, with a lower ONL thinning rate for the null allele group of 1.69 ± 2.44 μm/year compared to 3.20 ± 3.47 μm/year for the variant protein product group, P = .0437.
Within the low-risk group, the pairwise log-rank test between the Consistently Sufficient and Improving groups showed a borderline significant difference in EFS ( p = 0.0437, Figure 5A ).
4 , data from 8 RCT arms involving 607 participants (fluoxetine: 296; placebo: 311) showed a borderline significant decrease in HbA1c levels following fluoxetine treatment (WMD: − 0.61%; 95% CI: − 1.22 to − 0.016; p = 0.044), with significant between-study heterogeneity (I2 = 88%, p = 0.000).
This interpretation is supported by statistical analysis with ANOSIM which detected borderline significant clustering when all reactors were included (n = 4, R = 0.19, p = 0.044).
Furthermore, both the avascular and retinopathy subgroups exhibited significant or borderline significant variations in monocyte percentages ( p = 0.044 and p = 0.050, respectively).
The risk of a severe complication (Grade ≥ 3) was higher in patients with an additional intervention (24.2%) compared to patients without an additional intervention (6.6%, p = 0.011) and this was borderline significant when corrected for residual tumor size (OR 3.46; 95% CI 1.03–11.60; p = 0.044; Supplementary Table 3).
Pretreatment, high TNM Stage (S3–4) was borderline significant predictive of RFS (HR = 3.089 (95% CI 1.032–9.247), p = 0.044), whereas p16 status significantly predicted OS (HR = 4.257 (05% CI 1.128–16.064), p = 0.033), Table 3 .
Nutritional status, assessed using the abPG-SGA, demonstrated borderline significant improvement, with scores decreasing from 2.56 (SD 3.7) to 1.92 (SD 3.5) (mean change: −0.64 [SD 2.2], P = 0.044, Cohen’s d = −0.25).
Notably, Child‒Pugh class A patients showed borderline significant improvement over class B patients (74.4% vs. 60.0%; OR = 1.935; p = 0.044), suggesting that preserved liver function may confer cumulative benefits with repeated treatment.
In addition, also the R72P SNP in the TP53 gene showed a borderline significant difference regarding allele frequencies (OR=1.27; 95% CI 1.00–1.61; P =0.044) and the homozygote ratio (OR=1.77; 95% CI 1.00–3.13; P =0.04).
In addition, a significant reduction of the median oxLDLc [G2 (P = 0.002), G3 (P = 0.017) and G4 (P = 0.002)] and both oxLDL/LDLc and oxLDL/HDL [G2 (P = 0.009 & 0.001) and G4 (P = 0.018 & 0.002)] respectively was observed during follow up with a borderline significant reduction in G1 (P = 0.044) and G3 (P = 0.05) regarding oxLDLc and oxLDLc/HDLc respectively (Table 4 ).
Additionally, there were borderline significant differences in recorded race ( P = 0.044 by chi-square test) with patients in the LPT and E/VPT groups slightly more likely to have a recorded race of ‘Black or African American’ compared to FT patients (LPT: 65%, E/VPT: 65%, FT: 62%).
There was no significant difference in subsidence between genders, as later confirmed in the regression model, although the non-parametric test pointed to a borderline significant effect with females showing smaller subsidence (p = 0.044, Wilcoxon test).
Third, although abnormal EKG findings were significant in independent t-test and multivariate analyses, the sample was small and the p value was only borderline significant ( p =0.044).
HPV34 and HPV42 were borderline significant (p = 0.044) and non-significant (p = 0.069), respectively.
For the n = 35 scans from volunteers under 60 years old, there was a single borderline significant cluster of positive correlation between age and [ 18 F]FDG uptake in the right superior medial occipital lobe ( p < 0.044) and a single cluster of negative correlation centred on the superior frontal interhemispheric fissure ( p < 0.005).
This is further supported by our observation (details not shown) that when QRS- μf was used to predict first appropriate ICD shock rather than death in the EU-CERT-ICD data, the univariable prediction was only borderline significant ( P = 0.044, log 2 QRS- μf HR of 1.216 with 95% CI of 1.005–1.472).
Even though the risk for PTST– attributable to the chromosome 2 linkage region was only borderline significant ( p = 0.044), this 51-Mb segment accounted for approximately 9% of the overall risk for, PTST– and more than 40% of the total genomic risk.
RESULTS: Demographic parameters were statistically similar, except that they were borderline significant for gestational weeks at delivery (p=0.044).
We first estimated CRH mRNA levels in the central amygdala nucleus at the onset of the spasm-like events (P19) using ISH, and found a borderline significant difference between the rats that experienced CES and the control group (0.12 ± 0.01 and 0.08 ± 0.002, n = 3–4 per group; p = 0.044, Mann–Whitney test; Fig. 4 E). qRT-PCR analyses of dissected amygdalae (n = 8 CES, 7 controls) yielded large variances and no conclusive results.
There was a borderline significant effect of the communication ( β coefficient = 9.2 mm, 95% confidence interval = 0.3 to 18.1, p = .044) on anxiety during PIC placement in phase 2 (Supplemental Digital Content, Table S6), but not in phase 1 ( β coefficient = 1.6, 95% confidence interval = −6.8 to 10, p = .7; Supplemental Digital Content, Table S5).