Per-protocol analysis (12 patients and 14 patients in the fluvoxamine and placebo group, respectively) of the same outcomes showed no significant differences except for a borderline significant difference in the general fatigue domain of the MFI in favour of the placebo group (p = 0.04).
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One study used an MPD cut-off of exactly ≤5 mm, 34 without a significant association with CR-POPF (176 patients; OR 1.01, 95% CI 0.45–2.29, P = 0.97), whereas another study chose to classify glands with MPD diameter <5 mm as high risk, 53 with borderline significant results (100 patients; OR 3.14, 95% CI 1.07–9.26, P = 0.04).
Testosterone deficiency prevalence was markedly higher in the high-risk OSA group (43.83%) versus the low-risk group (12.70%), with a borderline significant association for the continuous OSA score (OR = 3.85, P = .04).
In bivariate associations, tau was positively correlated with age (ERC p < 0.001, metaROI p = 0.003; Figure S1 ) and there was a borderline significant effect of sex in the metaROI (F > M, p = 0.04) only.
Group II exhibited a mean NAS score at termination of 3.98±1.48, which is borderline significant compared to the initial NAS score (P=0.04073).
Paired t -tests revealed only borderline significant differences between SFG volumes as % in ICV in years 1 and 2 ( P = .041).
In contrast, fibrosis studies exhibited measurable publication bias, as evidenced by funnel plot asymmetry ( Supplementary Figure S7 ) and borderline significant Egger’s test ( p = 0.041).
There was also a borderline significant effect of age (age*presence/absence of infection χ 2 12 = 21.7, P = 0.041).
The number of non-responders between the five referrals centres was borderline significant at 6 weeks (p = 0.041).
Within the group of women with silicone implants and CTD (Group 1), between those women with paraproteins and those women without paraproteins there were only borderline significant differences or no significant differences (Mann–Whitney U test) in age (55.6 years versus 49.3 years, P = 0.041), in duration of CTD (10.4 versus 6.4 years, P = 0.051), in implant duration (10.2 years versus 12.5 years, P = 0.267), and in duration of silicone exposure (16.1 years versus 15.4 years, P = 0.783).
There was no association between CT density of LHIS and PCAT left ( p = 0.281), and a borderline significant association with PCAT right (Beta 0.227, p = 0.041; 95% CI: 0.010–0.445) and no association with total PCFV-density (Beta 0.568, p = 0.164; 95% CI: −0.236–1.37).
In contrast, clinical models were borderline significant (NPV = 0.64 (95% CI 0.59–0.69); HR = 1.37 (95% CI 1.03–1.81, p = 0.041); AUC = 0.57 (95% CI 0.52–0.62)).
ML-HDL appeared to be a concordant protective factor against cardiometabolic diseases (Cox HR IHD = 0.85 [95% CI: 0.83-0.87]; HR hyperlipemia = 0.88 [95% CI: 0.86-0.90]; HR hypertension = 0.90 [95% CI: 0.89-0.92]; HR T2D = 0.61 [95% CI: 0.59-0.63]), with a borderline significant causal effect observed between ML-HDL and reduced IHD risk (IVW β = −0.08, P = 4.1 × 10 −2 ).
Only one of the subscales, health perception, showed a borderline significant increase of 0.8 points ( P = .041).
When CSVD markers were adjusted for in model 3 (Table 7 ), all associations became insignificant, apart from a borderline significant association of PWV‐β with global cognition ( β =−0.27; P =0.041).
The one borderline significant association with AMHR2 and age ( P = 0.041) would not be considered significant after allowing for the number of characteristics tested.
Associations between SVG parameters and all-cause mortality were weaker than for the outcome of HF/CM, with only VGz having a borderline significant association (HR: 1.18 per 1 SD increase, 95% CI: 1.01-1.38; P = 0.042).
Finally, the type of PCAT attenuation used showed a borderline significant effect (QM(df = 1) = 4.15, p = 0.042).
A borderline significant prognostic association was confirmed in this dataset among all tumors, including those that were MSI (HR = 0.56, 95% CI 0.31–1.00, P = 0.042, Fig 6C ).
When we repeated the analysis using a continuous depression outcome (QIDS‐SR scores), our results did not change in magnitude or significance except for the identity model, where the main effect for the group was borderline significant, however with a similar effect size as for the main analysis ( ω 2 = 0.01, p = 0.042) (Supporting Information: Figure S1). 5.
24 , 25 A borderline significant survival benefit was seen with DD-M-VAC at an updated analysis of this trial [5-year survival rate 21.8% versus 13.5%; hazard ratio (HR) 0.76, p = 0.042]. 25 Finally, patients receiving DD-M-VAC had fewer neutropenia and febrile neutropenia episodes, without increased nonhaematological toxicities. 24 These results prompted a shift toward the preferential use of DD-M-VAC rather than conventional M-VAC when considering this four-drug regimen.
The primary MR analysis using the IVW method showed a borderline significant association between genetically predicted IPF and increased skin cancer risk (P=0.042).
However, the overlap between these sets was only borderline significant ( P = 0.042) ( Fig. 4 E, right), suggesting that this is more likely to reflect secondary effects compared with the coordinately activated gene set.
However, these differences, based on the categorized ADL, indicate only a borderline significant ( p = 0.042).
Analyses of ZBTB24 mRNA levels demonstrated that SZ LCLs express normal levels, while in RZ LCLs the levels were reduced at a borderline significant level (P value = 0.042, Fig. 4C ).