Barely Significant
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“borderline significance”

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borderline significanceP = .0350.7× alpha
45 Notably, the only triplet compared with Pom-Dex, pomalidomide-cyclophosphamide-dexamethasone, was in a randomized phase II trial with a weak surrogate primary end point (overall response rate) and borderline significance ( P = .035). 46 Given that Pom-Dex is relatively well tolerated, 47 , 48 and that toxicities are a serious concern for modern myeloma drugs, 49 our findings may have real-world significance.
borderline significancep = 0.0360.7× alpha
Sensitivity analyses addressing missing smoking data confirmed the robustness of this effect: HRs for smokers versus non-smokers remained around 1.9–2.0 with borderline significance ( p = 0.036–0.052), and although attenuated when “unknowns” were treated as smokers (HR = 1.53; p = 0.089), the direction of association persisted.
borderline significancep = 0.0360.7× alpha
In the multivariate logistic regression model, older age (AOR = 1.14; 95% CI = 1.05-1.25; p = 0.003) and absence of a family history of diabetes (AOR = 0.07; 95% CI = 0.02-0.27; p < 0.001) remained significant independent predictors of diabetes, while having a CD4 count <200 cells/μL also showed borderline significance (AOR = 0.14; 95% CI = 0.02-0.88; p = 0.036) (Table 4 ).
borderline significancep = .0360.7× alpha
In pregnant females, the regression with a Bonferroni-corrected significance level showed borderline significance on depression scores (EPDS) for both the left amygdala ( R 2 = .37, beta = .61, p = .036) and the right amygdala during downregulation ( R 2 = .38, beta = .61, p = .034).
borderline significanceP = 0.0360.7× alpha
However this result is limited by a low case number in each subgroup and showed a borderline significance: low risk subgroup P = 0.036, HR = 7.308, CI 95 1.168–45.703; other than low risk subgroup P = 0.027, HR = 7.442, CI 95 1.677–33.028, importantly due to multiple testing (k = 2) a P -value <0.025 is considered as statistically significant, Fig. 2a .
borderline significancep = 0.0370.7× alpha
However, pooling the XpYp data from labeled volunteers revealed that telomere lengths were maintained to a slightly greater extent in the CD57 − memory CD4 + T cell population compared with the CD57 + memory CD4 + T cell population ( Figure 3 D), and pooling the 17p data from volunteers in cohort 3 yielded a similar result with borderline significance (p = 0.037, Mann-Whitney U test; data not shown).
borderline significancep =0.0380.8× alpha
Results Association of Serum IL-35 With SLE and SLEDAI-2K Scores Serum IL-35 was elevated in SLE patients (median: 26.39 pg/ml; interquartile range, IQR: 22.48-34.84 pg/ml) compared with healthy controls (median: 24.85 pg/ml; IQR: 18.89-29.20 pg/ml) although with borderline significance ( p =0.038) ( Figure 2A ).
borderline significancep = 0.040.8× alpha
In another study of 362 patients with COPD who underwent cardiac catheterization and a 6MWD test as part of evaluation for lung transplantation, the prevalence of PH (mPAP >25 mm Hg and pulmonary arterial occlusion pressure <16 mm Hg) was 23% and 6MWD declined by 11 m for every 5 mm Hg rise in mPAP, but with borderline significance ( p = 0.04) ( 27 ).