“borderline significance”

The HR for OS was 0.55 (CI: 0.30 - 1.02) with borderline significance (P = 0.058) ( Fig. 4 ) in univariate analysis.

8D ), which is the major product of mouse Alox15-catalyzed DHA oxygenation, we observed a similar difference but for this metabolite only borderline significance was calculated ( p = 0.058).

On the other hand, when compared with triple negative breast cancers, a significantly lower risk of developing bone relapse was discerned for ERBB2+ women ( P = 0.048; HR = 0.384, 95% CI 0.148-0.991), with the borderline significance for HR+/ERBB2- breast cancers ( P = 0.058; HR = 0.479, 95% CI 0.224-1.025).

The data revealed that tumor staging was related with CNVs/mutation of m6A regulatory genes, and there was a borderline significance ( p = 0.058) between M staging and CNV/mutation status ( Table 1 ).

Subgroup analyses in high‐risk patients (i.e., those bearing T4 disease, N3 disease, or poor differentiation) revealed that a high NLR was a significant adverse risk factor for both OS and DC (all p < 0.03)—with a borderline significance being evident for DC in patients with T4 disease ( p = 0.058).

Meta‐regression Upon conducting multivariate meta‐regression with the subgroups defined above, we found patients in lower‐income countries to have significantly higher odds of worsening anxiety (aOR 8.94, 95% CI 1.62–49.28, p = 0.012) and reduced sleep (aOR 5.16, 95% CI 1.15–23.17, p = 0.032), as well as deterioration in PD symptoms with borderline significance (aOR 3.57, 95% CI 0.96–13.34, p = 0.058).

The RB signature was significantly correlated with an increased risk of 15% in the continuum (HR = 1.15, P = 1.1e-05), whereas the G3γ subtype exhibited the highest hazard ratio among all subtypes with borderline significance (HR = 2.55, P = 5.8e-02; Fig. 2e ).

Mean levels of IL-6 and IL-15 were also higher with a borderline significance in VAT of MS patients (4.07 vs. 1.43 ng per 1 mg of total protein, p = 0.058 for IL-6 and 0.063 vs. 0.043 ng per 1 mg of total protein, p = 0.07 for IL-15). 3.

In a study of the Chinese population, the probability of bone metastasis in patients with a HER2+ subtype was lower than in TNBC (P = 0.048), but there was only borderline significance compared with HR+/HER2− patients (P = 0.058) [ 25 ].

The statistical analysis, including a log-rank test, indicated borderline significance ( p = 0.058), with the lower dose cohort displaying a trend towards better survival outcomes. 3.3 Univariate analysis The univariate analysis detailed in Table 2 indicates that age was a significant factor for survival in patients with Gaucher’s disease.

Univariate analysis showed that pelvic wall invasion and rectal involvement were associated with DFS (p=0.002 and 0.044, respectively), and that resection margin status and bladder wall invasion did not show the significance but revealed the borderline significance (p=0.058 and 0.054, respectively) ( Table 3 ).

Plasminogen-activator inhibitor-1 (PAI-1; SERPINE1) was also downregulated at night-time, reaching borderline significance after adjustment for multiple comparisons (adjusted p = 0.058) ( Figure 6D ; Table S14 ).

The percentage of mice achieving a favorable functional outcome at 48 hours, defined as a score of <20 in the De Simoni composite neuroscore, was higher in the RIC+ group (49%) compared with the RIC− group (28%), but this difference reached a borderline significance level in the unadjusted analysis (absolute difference, 21%; odds ratio, 2.5 [95% CI, 0.97–6.1]; P =0.058) or when stratified by sex ( P =0.052).

4 with 5 months, 5 with 6 months, and so on, showed a significant time effect in the static, active and reactive trunk control of the infants at all ages (all p < 0.05), with the exception of a borderline significance in the active control between 4 and 5 months (Chi-square = 3.6, p = 0.058) and reactive control between 8 and 9 months (Chi-square = 3.6, p = 0.058).

Patients with high TFF3 expression had shorter OS compared to those with low TFF3 expression although survival benefits showed a statistically borderline significance ( p = 0.058).

In accordance with this finding of lower VEN/10 000 NN in neuropathologically earlier stages a moderate and inverse relationship between macroscopic severity and VEN density was found when ACC thickness was correlated with VEN/10 000 NN, with r s = −0.42 and borderline significance ( P = 0.058).

Even though none of these genetic polymorphisms significantly predicted tumor recurrence among these patients, EGFR:rs2227983, VEGF:rs2010963, and EGF:rs2237051 showed borderline significance for disease progression (P = 0.058 for EGFR:rs2227983, P = 0.073 for VEGF:rs2010963, and P = 0.104 for EGF:rs2237051; Table 2 ).

In conformity with Aβ immunoassay observations, Western blots of tau and α-synuclein did not show significant deviations between AD cases and ND-HPC ( Figure 6 ) although the 40–58 kDa tau isoforms had borderline significance ( p = 0.058).

Although the FIGO stage showed the most robust association with patient outcomes ( p <.001 for both PFS and OS), HIF2A expression also exhibited an independent prognostic value, with borderline significance for OS ( p = 0.058 for OS).

COPD was not a significant factor in the univariable analysis (HR: 2.36, 95% CI: 0.82–6.81, P=0.111) but approached borderline significance in the multivariable analysis (HR: 3.49, 95% CI: 0.96–12.76, P=0.058) ( Table III ).

Within the TIM4-binding method, we observed a similar trend with borderline significance ( p = 0.058).

Serum IL-6 levels, another inflammatory biomarker, was found to have decreased in a borderline significance manner over the period of the intervention ( p = 0.058) in BR alone group.

Protein content in feeds was not significantly correlated with crude fiber but showed borderline significance when compared to total fermentation time ( F 1,5 = 5.541, p = 0.058, R 2 = 0.543). 3.1.5.

Overexpression of AZI1 in the mpk3 background slightly improved its germination, as it showed borderline significance only at the day 4 ( p = 0.058) time point.

In addition, in multivariate Cox regression analysis, we found a borderline significance between worse survival and PLR ( p = 0.058) and dNLR ( p = 0.066).