“borderline significance”

Consistent with the previously published study ( Gursul et al., 2018 ), the gentle touch intervention resulted in a 39% reduction in the magnitude of the noxious-evoked brain activity, but a significant intervention effect was not observed (although the result indicated borderline significance) when baseline sensitivity was not accounted for, likely due to the lack of power with this sample size (linear regression, t = 1.95, p=0.05, Figure 3B , Study 2 indicates a power of 40% for a sample of this size without accounting for baseline sensitivity, Figure 2B ).

Compared with the subgroup at the highest quartile of tongue pressure, the crude OR for all the subgroups in the lower three quartiles was 4.17 (95% CI, 0.96–18.04), showing borderline significance ( p = 0.05).

This difference showed borderline significance (χ 2 (1, n =79) = 3.97, p = 0.05).

2.2 ± 0.2, p = 0.039) and the CRP-positive area was larger, with borderline significance (29.6 ± 6.3 vs. 13.7 ± 6.4, p = 0.05).

All cytokine/chemokine levels in SF were significantly higher in RA than in OA patients (P < 0.0001–0.003), except for IL-1β, the levels of which were higher with borderline significance (P = 0.05) ( Table 2 ).

Furthermore, the AAC haplotype for rs12083537, rs2228145 and rs4329505 of IL6R was strongly associated with a poorer response to TCZ based on the swollen joint count ( p = 0.00004) and with borderline significance of the EULAR response ( p = 0.05).

Interestingly, the only significant predictor of inflammation as diagnosed by pathology was the tCRM score (OR: 1.90, 95% CI: 1.40–2.68, p < 0.001), while having a male donor to female recipient was protective with borderline significance (OR: 0.27, 95% CI: 0.07–0.98, p = 0.05).

Patients with lung or mediastinal lymph node metastases only were more likely to achieve a radiologic response compared to patients with other metastatic sites (70% vs 42%; odds ratio 3.2; 95% CI 1.09–9.15; p = 0.033), with borderline significance for CR (20% vs 8%; odds ratio 3.7; 95% CI 1.00–13.83; p = 0.050).

Mortality In the high Hb target versus low Hb target trials, a borderline significance was detected in the risk of mortality with the high Hb group compared with the low Hb group (18 trials, 9859 patients; RR 1.10; 95% CI 1.00 to 1.21; P = 0.05).

Second, the small sample size (n = 8) and predominance of female patients limit statistical power for detecting small-to-moderate effects, increasing the likelihood of type II error for findings with borderline significance ( p = 0.050–0.058).

The overall risk of developing childhood asthma for a 10 μg/m 3 increase in prenatal PM 2.5 exposure was 1.12 (95% CI = 1.00, 1.26), with borderline significance ( P = 0.050) (Figure 2 ).

Similar trends were observed for each MACE component, whereas CV death showed a weaker separation, with borderline significance ( P = 0.05) ( Fig.

However, in the whole cohort, the level of apoA-I 110−525 was similar in patients with and without coronary atherosclerosis ( P = 0.29), since apoA-I 110−525 tended to be lower in the presence of atherosclerosis with a borderline significance ( P = 0.05) among patients taking LLM.

Additionally, Ki-67 and N-cadherin showed borderline significance ( p ≈ 0.05–0.07), suggesting potential differential expression.

The corresponding levels of the citrate synthase protein was reduced as well, similarly as the small mitochondrial ribosomal subunit MRPS31, both with borderline significance (P = 0.05) (Fig. 2b ).

A positive and significant association was found between PAI-1 rs2227631 and fecal incontinence (adjusted OR=3.172, 95% CI=1.490–6.751, P =0.003 for GG versus AA; and adjusted OR=2.541, 95% CI=1.249–5.170, P =0.010 for AG/GG versus AA), and borderline significance was shown for one variant allele (adjusted OR=2.108, 95% CI=1.001–4.440, P =0.05 for AG versus AA).

Borderline significance was found for rs1014290 and rs12498742 in GLUT9 during pregnancy ( p = 0.050 and p = 0.096, respectively, Kruskal–Wallis ANOVA).

Verbal fluency was modestly lower with borderline significance ( p ≈ 0.05–0.06).

By contrast, several exposures showed protective directions: phosphoethanolamine displayed borderline significance for reduced risk (OR = 0.75, 95% CI 0.56–1.00, P = 0.0500); serum-alanine-transaminase (ALT) was associated with lower risk (OR = 0.87, 95% CI 0.76–0.99, P = 0.0345); alpha-aminoadipic acid was linked to lower risk (OR = 0.75, 95% CI 0.59–0.96, P = 0.0208); leucine showed a stronger protective effect (OR = 0.56, 95% CI 0.34–0.91, P = 0.0197); and 25-hydroxyvitamin D 2 [25(OH)D 2 ] was likewise associated with reduced risk (OR = 0.81, 95% CI 0.70–0.94, P = 0.0045).

BWLWH in STEP-AD compared to E-TAU had significantly higher ART adherence (estimate = 9.36 p = 0.045) and lower likelihood of being clinically diagnosed with PTSD (OR = .07, estimate = − 2.66, p = 0.03) as well as borderline significance on higher CD4 count (estimate = 161.26, p = 0.05).

The association between higher hematocrit values and the hyperdensity of the PCA with borderline significance (p=0.05) was also observed.

Because the number of female quitters was small (N = 10), five metabolites that were measured in both KORA S4 and F4 showed borderline significance ( P <0.05).

First, the analysis of the Stage IIIA–IIIB subgroup was primarily driven by a single trial, resulting in a significant sample size imbalance between the neoadjuvant (n=88) and perioperative (n=406) arms; consequently, the borderline significance (P=0.05) should be interpreted with caution as an exploratory trend.

We noted a trend towards an improvement in the average MoCA score compared to the first examination by almost 2 points of raw score on average (23.13 vs 25.38 points) in the group of patients indicated and treated with CPAP, with a borderline significance result of p = 0.05.

In the present study, we found low levels of education in IGM patients with borderline significance ( P =0.05) in crude analysis.