“borderline significance”

In fact, I suspect the borderline significance of the 30 day findings would be lost (further supporting the authors’ assertions) using the correct but more stringent test. 4.

Norepinephrine dose at ICU admission (p = 0.048) and a higher percentage of used saline (p = 0.042) were also associated with ICU mortality, with borderline significance.

In respect of obesity, whether in general or specifically central obesity (waist circumference) these were related to both hypertension and diabetes status in men and women (with the exception of hypertension in women when sedentary behaviour was included as a covariate where it only attained borderline significance.) The strength of the relationship varied between the two genders – appearing broadly stronger in men than women.

Compared to borderline significance in GEE, the following relationships became significant: (1) between increasing ln serum cotinine levels and frequent night awakenings (PR = 1.28, 95% CI: 1.01–1.63, p = 0.04) in the age-adjusted model, (2) increasing ln serum cotinine levels and having ≥1 sleep disturbance (PR = 1.11, 95% CI: 1.00–1.24, p = 0.048) in the fully adjusted model, and serum cotinine levels ≥0.05 ng/ml and having ≥1 sleep disturbance (PR = 1.46, 95% CI: 1.00–2.12, p = 0.049) in the age-adjusted model.

31 Only among the subgroup of women who were in the <5 years postmenopausal stage, soy protein reduced carotid thickness progression by 68%, with borderline significance.

We previously found that femoral mode 4, which mediated the relation of sex with incident knee OA in the current study, was also found to have a borderline significance for difference by sex among persons without OA [ 11 ].

Although the Phylop score of KCNB2 :Glu522Lys showed borderline significance, the conservation percentage was still around 80%.

Post hoc analysis of data collected prospectively from PETACC-8 demonstrated the detrimental role KRAS mutation has on colon cancer outcome, being associated with a statistically significant increased risk of relapse and shorter DFS for codon 12 mutations and a borderline significance for codon 13 mutations [ 40 , 41 ].

The significance of this latter finding, which should be treated cautiously because of the borderline significance and the multiple adverse effects investigated, lies in its link to historical concern that inhibition of cholesterol synthesis would lead to risk of corneal opacity. 27 , 28 Epidemiological studies have suggested both increased and decreased risk of cataracts linked to statin use. 29 – 31 However, these studies will not have the length of follow-up available in WOSCOPS or the benefits of randomization in minimizing confounding factors.

It also enhanced the proliferation capacity of lymphocytes with borderline significance.

The borderline significance here might be attributed to the small number of SKCM patients treated with immunotherapy ( n = 73).

9–11 mm) with borderline significance.

However, NLR showed limited predictive value with borderline significance in the subgroup with high NLR cutoff values.

Hypoglycemia and pulmonary edema retained borderline significance under BH-FDR adjustment (q = 0.05) but did not remain significant following Bonferroni correction.

Likewise, although IFN-γ but not IL-10 induced robust STAT1-dependent induction of Cxcl9 , Cxcl10 , and Cxcl11 , the addition of IL-10 had quite modest which only attained borderline significance for Cxcl9 ( Fig. 7C ).

Glucose tolerance was also improved with borderline significance in STAT4-deficient mice on an HFD compared with wild-type controls ( Fig. 1 B ).

Borderline significance and interventional variability should be taken into account in statistical analysis because they may have an impact on the findings.

Only individuals with blood group AB had higher odds for the mild form of the disease (OR = 4.613, <0.108) with a borderline significance ( Table 4 ).

(2016), where a cohort of 355 patients was studied and using Cox regression analysis revealed that PCa patients with high PCAT-14 expression have better outcomes and are significantly associated with better prostate cancer specific survival (PSS), metastasis free survival (MFS), biochemical relapse-free survival (BRFS), with borderline significance for OS [ 92 ].

IL-6-to-albumin quotient: IL-6-to-albumin ratios were significantly greater in mcVAP/SuspulentVAP patients than in nonVAP patients on day 0, with borderline significance on day −1.

reported that acupuncture significantly improved FD symptoms as a monotherapy or add-on therapy and improved FD-related QoL as monotherapy but had no significant effect on plasma motilin with borderline significance (six studies; standardized mean difference 0.67, 95% CI −0.07 to 1.42; I 2 = 95%) ( 10 ).

Younger age (<18 months) and MYCN amplification were also associated with lower frequency of persistent BM tumor, but with borderline significance.

Significant associations do occur between two distant loci while inter- vening loci are excluded from the relationship, as shown for example by D1IS912/Dl1S935 and D1IS935/Dl1S922 (at borderline significance).

Despite this, the borderline significance of the findings in this study warrants the need for further investigation to clarify this relationship.

In our series, we could only demonstrate a borderline significance for the correlation of age and mortality, even though it is well known that increasing patient age is a strong independent predictor of mortality [ 15 ].