Several SNPs showing a strong association (but without genome-wide significance) and one SNP (rs2074633 in HDAC9 gene) with borderline significance were identified [ 17 , 36 , 37 , 87 ].
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“borderline significance”
In the literature
This is also reflected by the borderline significance of PD-L1 expression in multi-variable adjusted survival analyses in this study [ 36 ].
In the present study, only patients with stage III disease showed a difference in OS, but not RFS, according to the tumor location, with borderline significance.
However, after adjustments for other medical factors, bacteriuria retained an association of only borderline significance, and after further adjustment for demographic and social factors, the relationship completely disappeared.
Besides, the borderline significance of drinking status was found to be associated with the risk of HCC in both stages, with OR equal to 1.28 (95% CI: 1.06–1.56) in the combined analyses.
In addition, gender was included in the multivariable logistic regression model for upstaging due to its borderline significance in univariate analysis.
Variables with a p-value < 0.01 in univariate analysis, or showing borderline significance, were included in the multivariate model.
Nevertheless, it should be noted that this finding was at borderline significance; therefore, this improvement cannot be considered a relevant change in general coping pain strategies adopted by youths after diabetes camp.
Multiple plaques were not evaluated since they may have an impact on the associations between certain plaque features and ACIS and an influence on the borderline significance of the presented results.
Although only with borderline significance, we demonstrated that 3a tears had a mean ADC lower than that of 3b tears.
Similarly, the logistic regression model with GEE evaluating the probability of being seizure-free during the follow-up visits showed a borderline significance difference between the two treatment arms ( Table 6 ).
The transmission of the risk allele in the nuclear families confirmed the associations in INS , PTPN22 and CTLA4 ( JO27_1 ), although with borderline significance for JO27_1 (ESM Table 3 ).
However, due to its borderline significance and in alignment with clinical insights, smoking history was excluded from the model.
On the other hand, in 2013, the same authors measured the prognostic value of multiple screening tools for the assessment of 1-year mortality risk in 200 older women with gynecological cancer and found only borderline significance for the SPPB (AUC: 0.638; 95% CI: 0.483–0.792) in predicting mortality [ 83 ].
Moreover, we found that there were differences in participating in club activities between the two groups; intention to pursue higher education also showed borderline significance.
For our sample, the associations between categorization and compartmentalization with self-efficacy were negative but at borderline significance.
Three studies showed a significant positive association, while one study showed only a weak correlation and one study showed borderline significance.
However, due to a limited sample size, these associations did not reach conventional levels of statistical significance, although they approached borderline significance.
Muscle quality by CT area was lower in OVH subjects than in euthyroid and SCH subjects, with borderline significance.
In a recent paper on [ 68 Ga]-PSMA-11 PET-CT in recurrent prostate cancer, the employment of a LAFOV PET-CT system rendered 4 h late imaging feasible and demonstrated, as comparable to standard 1 h images, an improved TBR and improved SNR with a borderline significance at 4 h imaging while visual inspection was only modestly impaired [ 21 ].
This latter variable revealed a borderline significance in univariate analysis and was thus excluded from the final model.
Logistic regression showed that age was not a predictor of CTS, BMI had borderline significance, and smaller HRs along with thicker wrists significantly increased CTS risk. body mass index carpal tunnel syndrome hand ratio pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY OPEN-ACCESS TRUE SDC T 1.
This study also showed borderline significance regarding the positive correlation between age and log UMCR.
Notably, we explicitly state that the weak β coefficient and borderline significance highlight the need for caution, and that residual confounding from unmeasured factors may influence the result.
In our study, RVEF was a strong predictor of mortality in univariable analysis and showed borderline significance in multivariable models after adjustment for other CMR-derived indices, including RV/LV vol ratio.