Conclusions A statistical difference in antibody levels before and after vaccination (1st and 2nd measurement) for each test method was observed (therefore Null Hypothesis 1 is rejected), except for the first – Qualitative test, where the test power was low and the p-value at borderline significance.
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“borderline significance”
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The key clinical outcomes of retinopathy (borderline significance), nephropathy (UACR), established macrovascular disease, and mortality also varied significantly with G-gap status ( Table 1 ).
However, the three‐way comparison (Table 1 ) yielded borderline significance for fibrosis grades F = 2–4 only.
Among the variables included in this study, including maternal origin, socioeconomic status, birth weight of sibling higher than 3500 g and family size, only birth weight retained borderline significance ( Paltiel et al , 2004 ).
Baseline MVPA has been documented as a predictor of fasting insulin at follow-up, with a borderline significance for HOMA-IR, regardless of total sedentary time (Ekelund et al., 2009 ).
Despite it showing borderline significance and negative association with intervention effect in a systematic review of BCTs for healthy eating and physical activity [ 103 ], it has shown promise in a review of BCTs in alcohol and substance misuse [ 104 ], suggesting there are shared mechanisms between disordered eating and addictive behaviours [ 105 ].
There was a trend towards an association between greater CSA of psoas major (regression coefficient 3.6, 95% CI − 0.5 to 7.7, p = 0.08) and flexors total (psoas major and rectus femoris; regression coefficient 2.3, 95% CI − 0.3 to 5.0, p = 0.08) and better hip-related quality of life, achieving borderline significance.
Adiposome lipidomics; certain lipid species, including SM d41:1, PI 18:1/18:2; and PC 19:0 lipid species were higher in females (log 2 fold change [FC] = 1.4, 1.3, 1.1), though these differences showed only borderline significance after multiple-testing correction.
Although relatively strong effects of about −13% to 14% (depending on stratification) were observed with borderline significance, similar effects were found in the validation analyses.
In light of this finding, it is interesting to consider that in addition to the 2 significant effects at the 0.01-level regarding level of knowledge, differences in a further 5 statements achieved borderline significance (0.08–0.02).
Both p -values, although greater than 0.017, were lower than 0.05 and, therefore, can be interpreted as a trend (borderline significance).
Replace “borderline significance” by “tendency to”.
Most of the genes have not been reported to show borderline significance with BMI, as detailed in Table S2 .
Glucocorticoid use (P = 0.067), CD4/CD8 ratio (P = 0.011), and creatinine level (P = 0.066) showed borderline significance.
For urban areas, the deprivation index exhibited borderline significance when the neighborhood- and individual-level variables were controlled.
In our study, albuminuria was correlated (borderline significance) with the severity of coronary stenosis, but not with the calcium score or the number of coronary lesions.
Figure 4 [ 1 ] also separates the RCTs: their pool shows a borderline significance favoring statins for OC, and non-significant Std. mean difference for BALP and S-CTX.
Despite the early termination of the study, it is still part of the scientific debate, especially due to the borderline significance of the primary endpoint and the lower-than-expected recruitment.
The inverse relationship between sex and visual impairment became more evident, reaching borderline significance after adjusting for socioeconomic factors (OR: 0.52 [95 % CI: 0.25–1.06]; Model 3, Supplementary Table 3 ). 4.
Similarly, in our study, assuming that PVD generally occurs at a similar time in both eyes [ 17 – 19 ], the presence of TRD during vitrectomy was observed in patients with incomplete PVD evaluated by OCT in the fellow eye, although with borderline significance.
Positive signals with stars (*) indicate that there is a significantly higher amount of the metabolite in 13 C-enriched samples compared to natural abundance samples, whereas up arrowheads (^) indicate borderline significance. b) Amount of 13 C-labeled metabolites in the tumors, calculated by subtracting natural abundance spectra from 13 C-enriched spectra.
Furthermore, in ALS patients, plasma samples showed a significantly elevated exosomal TDP-43 ratio compared to baseline at 3- and 6-month follow-up and borderline significance at 12-month follow-up (Chen et al., 2020).
For OS only borderline significance was detected, which is most likely due to the small number of events.
The borderline significance of this finding may be due to our inclusion criteria requiring children to have either a history or presence of fever to be enrolled.
A negative correlation between TMZ’s effect and contrast volume ( R = -0.187, unadjusted p = 0.007, Bonferroni-adjusted p = 0.056, FDR-adjusted p = 0.017) hinted at dose-independent protection, retaining borderline significance with FDR.