“borderline significance”

When borderline significance was present in normally distributed variables, calculations with Student’s t -test were added.

Four SNVs in SLC15A2 were significantly associated with the estimated glomerular filtration rate in European ancestry populations, although these SNVs were related to the serum concentration of uric acid with borderline significance in our longitudinal EWASs.

Furthermore, GGO and consolidation showed a borderline significance of 0.06.

When we carried out the stratified analysis by fiber type, significant results were observed in soluble fiber and insoluble fiber but the result showed borderline significance in crude fiber.

Notably, idarubicin’s reproductive system adverse events (ROR = 4.0, PRR = 3.99, EBGM05 = 11.14) and epirubicin’s hepatobiliary toxicity (ROR = 4.99, PRR = 4.63, EBGM05 = 6.72) showed borderline significance with IC025 values of 0.28 and 0.5, respectively.

In addition, in model 2, where transaminases were categorized into ranges identified in the bivariate analysis (ALT ≤ 4,000 U/L and ALT > 4,000 U/L; AST ≤ 6,000 U/L; AST > 6,000 U/L), a significant association was found between higher chance of death and ALT > 4,000 U/L, and borderline significance for AST > 6,000 U/L.

T stage, which had a borderline significance in LRFS, was significantly associated with PFS.

from the Rotterdam study where one standard deviation increase in intracranial ICAC was able to predict the risk of dementia with borderline significance ( p -value: 0.05) and odds ratio confidence interval of close to 1 (1.34 (1.01–1.78)) [ 12 ].

Squint, posterior visual pathway tumor involvement, and bilateral pathway tumor involvement showed borderline significance.

33 The value of this adjustment is unclear because of the small number of evaluations available, limited number of patients, and borderline significance of the effect of hyponatremia on survival performed without age stratification. 20 Although hyper natremia was not the topic of our evaluation, we found that when the serum sodium concentration was above 140 mmol/L (142 mmol/L for the group II), there was an associated increased RR for death.

Mutational profile association with clinicopathological features and impact of treatment on mutation spectrum In the analysis of the 7-gene panel ( TP53 , TERT , IKZF1 , EP300 , MYC , EGFR and PIK3CA ) mutation spectrum and clinicopathological features in 123 OSCC patients, we identified two key gene mutations significantly associated with specific clinical characteristics, with an additional gene mutation showing borderline significance.

This may explain the slight inconsistency between the borderline significance observed in the highest quintile and the significant per-SD association, as categorization into quintiles can lead to information loss compared with continuous modeling.

Weight-Related Anthropometric Measurements At T1, one year after the surgery, there is a borderline significance for slightly lower weight for OAGB, as well as a trend for slightly higher BMI for SG groups.

Cigarette smokers in our sample initiated smoking at a younger age (borderline significance), and a substantial proportion of them (40%) smoked a pack or more daily.

Similar trends were also found in the female Mongolian population, in that moderate and heavy smoking had borderline significance in relation to Alzheimer's disease risk.

However, the association with the HLA‐DRB1*01 allelic group reached only a borderline significance, but this allele also had a very low prevalence in the MyEIRA sample (3.5% vs 26.5% in EIRA).

Association between CPPΔ and CBF parameters Day 0–14: CPPΔ was moderately negatively correlated with CBF% <10, CBF% <20 and mean global CBF with borderline significance.

Limitations Although this study offers meaningful insights into the distress and quality-of-life differences between breast cancer patients with high and moderate penetrance gene mutations, several limitations must be acknowledged to contextualize the findings appropriately and guide future research efforts: Sample size constraints: with 110 participants, the sample was relatively small, which may have limited the statistical power of the analysis, especially for variables with borderline significance.

Additional suggestive (borderline significance after FDR correction) candidates in SMC2 include rs10820599, rs10820605, rs966390, and rs7041529.

Final elevation in IL-6 levels also had borderline significance for worse survival.

Sensitivity analyses indicated that several studies (Fu 2024, Hu 2023, Xu 2019, Xu 2024) attenuated the pooled effect, while exclusion of Li 2024 and Hu 2023 reduced heterogeneity to 40.7% but resulted in only borderline significance.

Suicide attempt approached borderline significance (aOR 1.18, 95 % CI 1.00–1.39), while BMI (aOR 1.08, 95 % CI 0.98–1.20) and smoking (aOR 1.07, 95 % CI 0.97–1.18) were not significantly associated with only-child status.

2 Age over 40 years was not an independent risk variable for leukaemia, while a borderline significance was observed between increasing age and increased risk of subsequent leukaemia when the age was analyzed as a continuous variable.

This is similar to the findings of Merchant et al, who reported a borderline significance for a number of tumor surgeries. 27 Complete resection can be challenging.

Similar patterns were observed, and the empagliflozin add-on therapy demonstrated superior efficacy compared with the sulfonylurea dose-increasing strategy with borderline significance ( Supplemental Table S1 ).