“borderline significance”

The effects of anti-PD medications on the gut microbiota One recent study found a significant difference in the gut microbiome as a function of treatment with COMT inhibitors and anticholinergics, and a borderline significance for carbidopa/levodopa [ 119 ].

Following stratification of genotypes according to reported current use or non-use of hormone replacement therapy, rs13281615 (8q24) was significant only in non users of HRT with a p-for interaction of 0.03, indicating borderline significance (Table 4 ).

The gene MAP1 LC3B was significantly upregulated in PERBC using FDR-adjusted p-value (< 0.05) and TLCD2 , EPHX1 , and PCDHA were upregulated with borderline significance (FDR = 0.084-0.092).

placebo) had borderline significance in the arm circumference group only. 3.4.

We dealt with multiple comparisons as recommended by Perneger 57 by transparently reporting all results, including those with borderline significance.

Statistical significance was defined as α = 0.05; borderline significance was identified as α = 0.10.

Presence of pars planitis (odds ratio 4.4, 95% confidence interval 1.4–13.9, and p = 0.012) and high myopia (spherical equivalent less than −6 diopters or axial length longer than 26 mm, odds ratio 3.4, 95% confidence interval 1.1–10.9, and p = 0.038) were significant factors associated with primary anatomical failure and pseudophakia (odds ratio 3.0, 95% confidence interval 0.9–9.7, and p = 0.070) showed borderline significance ( Table 3 ). 4.

The exception was patients on NSAIDs monotherapy, which presented a subtly worsening effect on symptom burden with borderline significance (RRa 1.22, 95% CI: 1.01–1.46).

Lymphocyte count (aOR, 0.973; 95% CI 0.947–1.001; p = 0.059) and age (aOR, 1.01; 95% CI 0.998–1.028; p = 0.097) showed borderline significance.

In this sample, the restricted variability in AUDIT-C scores and the small number of adolescents drinking alcohol likely reduced statistical power and may explain the borderline significance and lower effect size that was detected relative to the other samples.

There was a lack of participants and non-participants to compare according to the main sociodemographic and clinical characteristics that could result in any type of bias, a lack of baseline clinical characteristics that could indicate any possible sitagliptin residual effect before the beginning of a cross-over design and a sample size since borderline significance in some comparisons could be attributed in part to the relatively small number of participants.

Moreover, visual neglect had borderline significance as a single predictor.

Despite the statistical borderline significance, the small effect size and absence of a large clinically significant difference suggest limited implications for generalizability.

Two additional loci (FNI and 2p14) demonstrated borderline significance in moderate-to-severe cases [ 30 ].

The Longevity Association of rs1063192 ( CDKN2B-AS1 ) Replicates With Borderline Significance in an Independent Cohort We aimed for replication of the association results in 2 independent cohorts.

10 The borderline significance of this study results may be attributed to the unequal distribution of BMI among the participants.

The water had 97% higher tannin content in the cattle dung treatment and 13% less in the fertilizer treatment (borderline significance) compared to the control.

One study has reported a borderline significance between the plasma tumor DNA and DFS in multivariate analysis with tumor size, lymph node and tumor stage (Silva et al. 2002b ).

5 ) A prospective online survey conducted 12 months after recovery found that female sex showed borderline significance for cognitive impairment risk. 38 ) The Atahualpa cohort study from Ecuador reported no female predominance in reduced cognitive performance at 6 months in individuals recovering from mild symptomatic COVID-19 infection. 40 ) The reason why female sex emerged as a negative factor in our study may be because men tend to have more severe COVID-19 than women. 41 ) At the beginning of the study, individuals experiencing more severe conditions may not have been included because they failed to meet the inclusion criteria.

We segregated them into the minimal change disease / focal segmental glomerulosclerosis groups and observed that the ACE ‘D’ allele was identified with borderline significance in cases of focal segmental glomerulosclerosis and the ‘I’ allele was assessed as having very weak association in cases of minimal change disease. ‘II’ genotype was weakly associated with minimal change disease.

Finally, for the pre-defined gene sets we detected borderline significance for the Medial Prefrontal Cortex tissue ( P BH = 0.05).

Four other chronic disease pairs were found to be particularly associated with noncompliance with the PA guideline at a borderline significance level.

Our previous metabolic efforts with a prospective cohort study comprising mostly smokers confirmed CR as predictive of the lung cancer risk before radiographically visible cancers and NANA displaying borderline significance.

to <10 years’ group had an adjusted HR of 1.62 (95% CI 1.04, 2.53, p =0.033) and 1.52 (95% CI 1.02, 2.27, p =0.040) for CKD and cardiovascular–kidney disease, respectively, while the ‘top-20%-wPRS plus baseline DD<5 years’ group had an adjusted HR of 1.63 (95% CI 0.93, 2.87, p =0.089) for CVD, with borderline significance.

Numerous analyses showed borderline significance and were not used to support our conclusion, as they may indicate the involvement of ILs of the Th1 pathway in the immune response to HBsAg.