Particularly, the median survival in patients with both mutations ( FLT3 -ITDm/ NPM1 m) was 98 months [OS at 3y and 5y 60% +/− 8 (SE) and 56% +/− 8 (SE), respectively], worse than in the FLT3 -ITDwt/ NPM1 m, with a borderline significance ( p : 0.06) [in the ITDwt/ NPM1 m: the median survival was undefined, at 3y and 5y OS 80% +/− 4.8 (SE) and 71% +/− 6 (SE), respectively].
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“borderline significance”
In the literature
A previous study that evaluated the use of texture analysis as an alternative for characterising SVD and assessing possible blood brain barrier leakage ( Valdés-Hernández et al., 2017 ) reported differences in the texture of the FLAIR deep grey matter between post-acute lacunar and cortical stroke patients, but only with borderline significance.
For Q1, unemployment presented a borderline significance.
Coinfection (OR 3.493, 95% CI 0.814–14.998, P = 0.092) had borderline significance (Table 4 ).
However, the multivariable associations for the secondary endpoint and all‐cause hospitalizations crossed the nominal significance threshold and retained only borderline significance.
Inverse associations of selenium and FVC, and positive associations of selenium with FEV1:FVC were consistent in analyses using liters/second and those using percent predicted pulmonary function as well, although in both analyses, the positive association with FEV1:FVC was of only borderline significance.
RDW was the only marker significantly associated with 3-month mortality and showed borderline significance at 1 year, with optimal cutoff values of 15.05% and 13.65%, respectively.
One study examined workers in chrome production [ 118 ], where the measured airborne concentration of hexavalent chromium was on average 9 μg/m 3 , reporting increased risk of 1.22, with a borderline significance.
Postoperative pain at 4 h and 12 h were in favor of SA following either open or laparoscopic repairs (standard mean difference [SMD]: 1.58; 95%CI: 0.55, 2.61, SMD: 0.99, 95%CI: 0.37, 1.60, respectively); and considering borderline significance, patients receiving SA might be more satisfied with the anesthesia they used for herniorrhaphy (SMD: -0.32, 95%CI: − 0.70, 0.06).
In a meta-analysis, sodium bicarbonate was found to be protective against CI-AKI but with a borderline significance[ 63 ].
Results Significant correlations for overtime correlations between population-levels of opioid dispensing and opioid-related hospitalizations were observed for three provinces: Quebec ( r = 0.87, CI: 0.49–0.97; p = 0.002); New Brunswick ( r = 0.85;CI: 0.43–0.97; p = 0.004) and Nova Scotia ( r = 0.78; CI:0.25–0.95; p = 0.012), with an additional province, Saskatchewan, ( r = 0.073; CI:-0.07–0.91; p = 0.073) featuring borderline significance.
Among other prognostic factors, smoking (HR = 1.48, P = 0.061) demonstrated borderline significance, representing a strong trend.
Significant associations have been observed in Asian populations [ 10 ] and borderline significance has been observed for Caucasian [ 11 ] populations, while there have been no significant findings among African populations [ 10 , 11 ].
Multivariate analyses were performed on the data that showed significance and borderline significance in univariate analyses.
Additionally, the pathways ‘α-Klotho → obesity → T2DM → CVD’ ( p = 0.064) and ‘α-Klotho → obesity → CKD → CVD’ ( p = 0.061) showed borderline significance, implying a potential but less pronounced mediation effect.
This statistical association was at borderline significance in a multivariate regression analysis.
The GSE37642 and GSE12417 databases, both containing microarray-based gene expression data of patients with AML (n=136 and n=240 patients) showed that high CD163 expression was associated with poor prognosis, although the significance level reached only borderline significance ( figure 4D ).
In the sensitivity analysis that included CCI as a covariate, there were comparable effects of BMI, with borderline significance for decreased OS in the underweight group compared to the normal group (HR 2.12, 95% CI: 0.99, 4.53).
The OS rate was higher in group receiving metronomic chemotherapy than in group receiving palliative treatment at 6 and 12 months with borderline significance (6 months HR 0.60; 95%CI 0.36, 1.02; p-value 0.060; 12 months: HR 0.66; 95%CI 0.41, 1.08; p-value 0.097).
235.01 ± 77.56 W, p = 0.046) was greater in the CT group though this difference should be interpreted with caution given its borderline significance. suggesting a potential advantage in baseline lower limb flexion strength for CT carriers.
1 , the Egger's regression test did not show statistically significant asymmetry of the funnel plots (except for a borderline significance for the eligible studies with available data for in-hospital mortality analysis), thus suggesting that publication bias for the main clinical outcomes of interest (panels A to C) was unlikely.
For AC databases, sexes were combined because there was only borderline significance seen in the apical region between sexes.
The evolution factor proved to be significant, or showed a borderline significance value, for the following brain regions: parietal and temporal lobes bilaterally, precuneus.
(2013) found a tendency towards a higher occurrence of the C (Val) allele of rs6265 and borderline significance for the Met/Met genotype in patients with bipolar disorder, type I (BD-I), bipolar disorder type II (BD-II), and schizoaffective disorder, bipolar type.
Overall, high miRNA expressions were associated with homogenous low sHLA-G levels, while low miRNA levels were associated with largely variable sHLA-G levels, which contributed to the borderline significance of the differences.