In our study, the subclassification of subjects in NPD or PD according to HbA1c (< 5.7% and 5.7 – 6.4%, respectively) and/or FPG (< 100 mg/dL and 100 – 125 mg/dL, respectively) levels showed that both NPD and PD under either treatment scheme had similar weight loss time-courses, with borderline significance to greater reductions in the PD-MM subgroup (10.2 kg at month 6).
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“borderline significance”
In the literature
The PFS was better, with borderline significance, in patients that received second line bevacizumab compared to those that received third or later line bevacizumab (5.0 vs. 2.4 months, hazard ratio (HR) 0.49 [95% CI, 0.23–1.05], P = 0.060); the OS was not statistically different according to the line of bevacizumab treatment (16.4 vs. 11.2 months, HR 0.67 [95% CI, 0.24–1.83], P = 0.426).
Due to the overlapping confidence intervals and borderline significance of these results, comparisons among all ETDRS sectors revealed no significant spatial biases.
The borderline significance of the interaction between COMT genotype and childhood trauma indicates that chance should be considered a possible explanation of this interaction, though the test for interaction is conservative, making this less likely.
Table 5 showed the results of this sensitivity analysis; risk predictive model of purposed concurrent genes delivered the best discriminative power while borderline significance was observed for the model driven by the Oncotype DX TM signature genes.
Multivariable logistic regression indicated no statistically significant association between the most important baseline clinical parameters and the occurrence of the arrhythmias listed in Table 3 ; however, for high-voltage injury borderline significance was detected (Table 4 ).
High concentrations of 16S rDNA showed borderline significance ( p -value 0.053).
Additionally, lower previous exercise engagement demonstrated borderline significance, suggesting potential greater intervention-related neurophysiological benefits in individuals less physically active at baseline.
After adjusting for covariates, disorganization symptoms showed a positive association at borderline significance with relapse during pregnancy (adjusted odds ratio [aOR] = 1.36; 95% confidence interval [CI] = 0.99–1.87 per unit increase in number of symptoms) and depressive symptoms negatively with relapse postpartum (0.78; 0.62–0.98).
No significant association was observed in the Celera sample set at the 0.05 level, but there was a borderline significance in the Thessaly sample set ( Table 2 ).
The predictive power of NPTX2 for cognitive progression was at least comparable to that of Nfl and was consistent across measures of memory, global cognition, and CDR ( Supplementary Table 4 ), whereas Nfl had strong predictive value for ADAS-cog and borderline significance for other tests.
Having previously been diagnosed with an STI showed borderline significance (OR = 2.2, 95% CI: 0.9 – 5.5).
51 , 52 This approach risks discarding data with borderline significance, whereas machine‐learning models rely on the additive effects of both strong and weak predictors, 29 which may additionally explain why these models perform better.
Ventricular dimensions and function All absolute and indexed chamber dimensions were significantly larger in men, except for LVESV/BSA with only borderline significance ( Table 4 ).
Reduction of Mgp expression was statistically significant on the Biomark HD platform, in contrast to the TaqMan analysis, suggesting a borderline significance of this result in concordance with the RNA-Seq DEG results.
However, these were not pursued further due to their borderline significance.
However, some individual terms demonstrate borderline significance in the sunflower oil samples.
Previous gynaecological surgery and old age increase the risk of complications with borderline significance (OR = 2.5, 95% CI: 0.97–6.3; OR = 2.3, 95% CI: 0.95–5.5 respectively).
Log Gal-3 (β= 4.486; P=0.095) only showed borderline significance.
As the evidence also suggests for individuals following healthy aging trajectories, individuals in this cluster mostly used health-promoting coping mechanisms, such as active problem-solving strategies (of a borderline significance) and positive emotional and/or cognitive appraisal of stressful situations (indicating by positive reframing), which might have rendered them capable of diminishing the hazardous effects of emotional distress on the body and mind, and of slowing down the development of comorbidities ( 28 ).
Considering the clinical context is imperative, it is essential to interpret the results cautiously, especially for genotypes or alleles with borderline significance levels.
As shown in Table 2 , after the adjustment of the other baseline variables, age (HR= 1.04, 95% CI 1.00–1.09) and cigarette smoking (HR= 2.68, 95% CI 0.94–7.63; a borderline significance) were found to be the two most important predictors of an increased risk of liver cancer after 15.9 years of follow-up among these study subjects.
Data Analyses All analyses were conducted in SPSS version 22.0 (IBM Corporation) and significance was set at P <.05, while P values between .05 and .10 were interpreted as indicating borderline significance.
With respect to preoperative MRI findings, multifocality (odds ratio [OR] = 3.977, p = 0.009) and NME (OR = 2.741, p = 0.063) were associated with positive resection margins in the multivariable analysis, although NME showed borderline significance.
While this has only borderline significance, similar results were obtained with repeated trials.