In particular, associations of rs398652, rs1975174, or rs2735940 with telomere length showed borderline significance in the present study.
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“borderline significance”
In the literature
Also the conclusion, with borderline significance statistically, may be correct for Her-2 enriched subgroup in comparison to luminal subtypes.
In Chinese-Americans we observed significance in the association of rs10846744 with Lp-PLA 2 activity, while in Caucasians we observed borderline significance with Lp-PLA 2 mass.
Still, the interpretation needs to be dealt with caution, given a borderline significance level identified.
14) However, as the risk of MI was decreased in the pooled analysis of RCTs with borderline significance and previous studies suggested improved outcomes in mortality and MI with the use of preoperative aspirin in long-term follow-up, we could not exclude the potential benefit of preoperative aspirin. 5) , 6) , 7) The long-term follow-up data of the ATACAS trial will provide additional insight.
The level of significance was set at 0.05 and 0.1 for borderline significance.
Not having Swiss nationality achieved borderline significance as a predictor of lower rates of repeated participation in trial participants.
The degree of kinship showed a meaningful association: the caregivers who were spouses of care recipients had significantly higher odds of reporting an abnormal caregiver burden (AOR 2.755, 95%CI: 0.833–9.111), although the confidence interval suggests borderline significance.
( 22 ) demonstrated borderline significance of hypertriglyceridemia to be related with the progression of renal disease in chronic renal failure patients.
Additionally, the major allele A was associated with increased likelihood of achieving EULAR good and moderate response under the dominant model with borderline significance ( Table S4 ).
[ 25 , 26 ] On the contrary, Khedr et al found that vitamin D was higher in children with CHC than normal controls with borderline significance; this difference may be due to milder state of liver infection in their patients’ group than our groups.
However, the highest tertile of accelerometer-based sedentary behaviour had borderline significance with higher psychological distress using the K6 (adjusted OR = 1.93; 95% CI = 1.00–3.75, p for trend = 0.04), whereas no significant association was reported for GHQ-12 psychological distress.
Smoking cessation inequalities by income in 18–30 year olds increased with borderline significance during the GFC (OR low income compared to high income: 0.73[0.58-0.91]) compared to pre-GFC (OR: 0.98[0.80-1.20]), p for interaction = 0.051).
The tumor AKR1B1 score was significantly higher in proximal tumors compared to distal tumors ( p : 0.046, Turkish cohort, Figure S9E ) and in mucinous tumors as compared to nonmucinous tumors with borderline significance ( p : 0.056, Serbian cohort, Figure S9F ), which may be due to the presence of mucinous tumors more often in the proximal colon [ 21 ].
26.62 years, P = 0.056), although only borderline significance was noted.
Parental rule-setting (only among adolescents), monitoring, and emotional support were protective factors and, although with a borderline significance, the absence of a parent was a risk factor.
The incidence of platelet engraftment tended to be lower in the high‐ferritin group than in the low‐ferritin group, with borderline significance (Fig.
Interestingly, at the time of the current survey, Pf LIgG levels were—with borderline significance—still higher in the placebo group ( Table 1 ).
Network analysis methods, such as DSPC and others employed in the present and previous studies, are expected to shed light on these borderline significance differences and especially their association with related phenotypical traits, such as dysfunctional TCA with fatigue in Hashimoto.
Following the stratification by tumor site (colon / rectum) we found that rs1525489 showed a marginal/borderline significance with increased risk of rectal cancer at nominal level of (P trend = 0.0071), while the associations between the SNPs and colon cancer were similar to those considering the two strata together (Table 2 ).
In the control group we found a significant negative correlation with triglycerides levels (r=-0.390, p<0.05) and a trend for positive association with HDL-cholesterol (r=0.201, p=0.09), with borderline significance.
For rs238406, however, we found a statistically significant trend for the allele G → T effect on ERCC2 mRNA expression in Europeans ( P trend = 0.011) but a borderline significance in CHB ( P trend = 0.098).
Other pathways, including Nucleotide metabolism ( P adj = 0.051) and Gap junction ( P adj = 0.053), showed borderline significance.
Discussion Our results indicate that hippocampal atrophy may mediate the association between NECTIN2 polymorphism and AD risk, although the borderline significance of these associations warrants confirmation in other populations.
However, those diagnosed by a physician were younger, had more episodes, experienced more severe and painful symptoms, and reported a greater interference in their daily life (borderline significance) during the pretreatment period.