Levels of HIV-risk related measures did not significantly differ between study arms at baseline; although median episodes of unprotected sex with commercial partners in the preceding 6 months were somewhat higher at intervention beer halls (median 1.5, IQR 0.1–2.8) compared to controls (median 0.2, IQR 0–0.5), a difference that achieved borderline significance ( P = 0.10).
Predictors of lower three-vessel mean MRR Univariable analysis showed only prior MI was significantly associated with lower three-vessel mean MRR ( P = 0.007), while diabetes and current smoking showed borderline significance ( P < 0.10).
There was a trend of higher alpha diversities (number of species, Chao1 and Shannon index) for CRA + compared to CRA- with a borderline significance (0.05 < P < 0.1).
Other variables with at least borderline significance ( P < 0.1) were disease in vitreoretinal lesions (HR, 0.38; 95% CI, 0.17–0.84; P = 0.017) and peak total bilirubin ≥ CTCAE grade 3 (HR, 3.02; 95% CI, 1.38–6.58; P = 0.006).
However, in multivariate analysis including variables with borderline significance (p < 0.1), high CMV DNA load was associated with the improvement of DFS (HR 0.51, 95% CI, 0.27–0.91, p=0.024).
Moreover, overexpression of the LDLR in the primary human hepatocytes appeared to promote apo(a) internalization, although at borderline significance (p = 0.10) ( Fig 2B ).
Multivariable Cox analysis was performed to identify the independent prognostic factors by incorporating the variables with borderline significance or significance ( P < .1) in the univariate Cox analyses.
In addition, the number of epileptogenic zone (p = 0.057), although not significant at the conventional 0.05 level, demonstrated borderline significance (p < 0.1) and was therefore included for further evaluation.
Predictors demonstrating statistical significance ( p < 0.05), borderline significance ( p < 0.1) or strong clinical relevance in bivariate analyses were considered for entry into multivariable logistic regression models, constructed separately for each outcome.
Factors associated with at least borderline significance ( P < 0.10) in the univariate analysis were subjected to a multivariate analysis.
Factors with significance or borderline significance ( p < 0.1) in the univariate analyses and those related as pertinent factors in the literature were then included in a multivariable regression model with backward stepwise variable selection.
Subjectively, those with “borderline significance” (p<0.10) were included.
Multivariable Cox proportional hazards models incorporated significant variables and covariates demonstrating borderline significance ( p < 0.10) in preliminary univariate analyses.
Differences were considered significant at P < 0.05, with borderline significance considered at P < 0.10.
Variables reaching statistical significance or borderline significance ( P < 0.10) in the unadjusted regression were included in a multivariate model adjusting for possible confounders through forward stepwise logistic regression.
The analysis proceeded in a stepwise manner, beginning with age- and sex-adjusted univariate regression models for each inflammatory parameter, followed by a multivariable model including biomarkers that demonstrated at least borderline significance ( p < 0.10) in univariate testing.
In the case of salinity and muscle-weight, borderline significance was observed ( P < 0.10), while the rest of the fixed effect parameters showed P -values lower than 0.001 ( Table 5 ).
Statistical significance was defined as p < 0.05 and borderline significance as p < 0.10.
The decrease in miR-98 showed statistical borderline significance (0.05 ≤ p ≤ 0.1).
Adults with hypertension scored on average 2.32 points lower (95% CI: -4.84–0.21) on physical health QoL compared to the healthy group and this difference had borderline significance ( p < 0.10).
ALR increased as DMNQ was increased (F(4,84)=5.44, P <0.001) with this increase significantly greater in AD LCLs (F(4,105)=3.97, P <0.005), due to significantly higher ALR in AD LCLs at 10 μ M ( t (105)=3.86, P <0.0005) with borderline significance at 12.5 μ M ( t (105)=1.78, P <0.10).
After incorporating interactions between bone lead and genotypes into the models, we found that 5 and 4 polymorphisms reached statistical significance (p<0.05) and borderline significance (p<0.1), respectively, when genotypes were modeled as additive ( Table 3 ).
While the EPHA2 signal showed the trend towards increase upon irradiation in all compared categories (adherent HCC-44 cells, adherent A549 cells, and A549 spheroids), the increase was not statistically significant due to high variation between the experiments; in case of HCC-44, borderline significance was achieved ( P < 0.1).
All four EET isomers analyzed showed borderline significance ( p < 0.1) in the mental scale with positive coefficients.
Variables that were significant or with borderline significance (p ≤ 0.1) were included into the multivariate model.