Although the interaction between MASLD and insulin resistance showed only borderline significance after multiple testing correction (adjusted p = 0.09), the direction and magnitude of the effect (OR = 2.02) align with mechanistic hypotheses positing insulin resistance as a shared driver of both MASLD progression and renal injury.
Interestingly, levels of glycine ( p = 0.02; Figure c), phenylalanine ( p = 0.01; Figure d), tryptophan ( p = 0.01; Figure e), and glutamine ( p = 0.02; Figure f) were significantly lower in abundance in FA-treated samples, with tyrosine showing borderline significance ( p = 0.09).
Female participants showed a marginally elevated infection risk (OR = 1.27, p = 0.35), while communal cup-sharing behavior demonstrated borderline significance as a risk factor (OR = 1.95, p = 0.09).
However, in the standardized model which included all standard prognostic factors regardless of their statistical significance, the magnitude of this association decreased and was of the borderline significance (p = 0.09).
Borderline significance ( p = 0.09) was seen for higher N-stage (N2-3) and higher ΔSCD 2% .
The killing of D6-iPSC2 cells by NK cells of donor 5 appeared also to be reduced but only at borderline significance (panel D in S10 Fig ) (P = 0.09, t -test).
Furthermore, borderline significance was shown between MDA status and tumour grade ( p = 0.09).
The newer chemotherapy regimens showed increased TRDs in CCRT compared to other regimens with a borderline significance (OR = 0.40, 95% CI: 0.14–1.15, P = 0.09) ( Fig 3B ).
The prevalence of doctor-diagnosed asthma was low in Shanxi (0.9%), and the prevalence in urban schools was higher than in rural schools, with borderline significance (1.2% vs 0.2%, p = 0.09).
While, plasma levels of both CTRP5 and adiponectin with a borderline significance, was lower in T2D patients in comparison with controls (P = 0.09 and P = 0.094 respectively).
While our Egger's test for the mortality outcome showed a borderline significance (p = 0.09), which suggests the presence of small study effects, it's critical to approach these findings with caution.
In the multivariate analysis depicted in Table 1 , this variable also showed borderline significance (p = 0.09) as independently associated with HCV infection.
Compared with patients with relatively stable eGFR Cr+CysC (Q3), those with decreased eGFR Cr+CysC (Q1) exhibited significantly increased adjusted risk of death (hazard ratio [HR], 1.96 [95% CI, 1.27–3.04], P =0.003) and those with increased eGFR Cr+CysC (Q5) exhibited borderline significance (HR, 1.51 [95% CI, 0.94–2.42], P =0.09), after adjusting for confounders, including baseline eGFR Cr+CysC and albumin‐to‐creatinine ratio.
Glucagon-like peptide-1 receptor agonist usage (11.8% of patients with DM patients) compared to no-DM controls achieved borderline significance as a risk factor for preparation inadequacy (OR 2.148, 95% CI 0.887–5.201, p = 0.090).
There was a trend to borderline significance between overweight status and serious events with an OR at 3.81 (p = 0.09) ( Table 4 ). 4.
Graft survival was lower in vascularized corneas (18.55 months, P = 0.030) and in post-perforation corneal scars (17.96 months, P = 0.09, borderline significance).
The median OS in male recipients of stent-limiting treatment in groups A was better than group B with borderline significance (30 months vs 16.75 months; p = 0.091; HR: 0.303, 95% CI: 0.046–2.013) (Fig. 3 ).
A similar association was observed for chronic musculoskeletal pain in the same subgroup, showing borderline significance (14.6%, 20.3%, and 22.4%, respectively; p = 0.091) ( Supplementary Table S4 ).
Moran’s I rise to a higher band (about 0.059-0.094), and borderline significance emerges in key years (e.g., 2011 p = 0.091; 2017 p = 0.089).
In the control group, bone union was achieved in 51% of patients; the Ilizarov group and the control group differed in terms of the median time to union (203 days and 271 days, respectively); however, this difference reached only borderline significance ( p < 0.091).
Secondary descriptive parameters showed similar trends, with significant increases in %DNA in tail at days 6 and 11 (day 6: β = −0.320, p = 0.042; day 11: β = −0.367, p = 0.011), whereas changes in TL were small and reached only borderline significance at day 11 ( p = 0.091).
While 120-minute insulin levels showed only borderline significance in the highest quartile (OR = 1.29, 95% CI: 0.96–1.72, p = 0.0910), 120-minute C-peptide levels were significantly associated across quartiles, with Q3 exhibiting elevated odds of advanced CKM stages (OR = 1.60, 95% CI: 1.20–2.15, p = 0.0016).
Values of FF in the LAs in the DTs that demonstrated benefit of adding PWI to WA-PVI were higher than those in the DTs that did not have that benefit, with borderline significance (LA FF: 19 ± 6% vs. 15 ± 6%, p = 0.091) (Fig. 4a ).
Age was negatively correlated with serum PON1-paraoxonase activity with borderline significance ( P = 0.091), and ever-smokers had lower serum PON1-paraoxonase activity than never-smokers ( P = 0.005).
Female preponderance to psychomotor retardation and slow thought showed borderline significance ( P =0.091 and 0.078, respectively), but noticeable psychomotor retardation appeared to be significantly more frequent in women (28.4% vs. 39.0%, P =0.032).