Notably, the association between the TyG index and all-cause mortality attenuated to borderline significance after full covariate adjustment (HR = 1.57, 95% CI: 0.95–2.59, p = 0.080), suggesting that the mortality risk may be partially mediated by traditional risk factors such as age, diabetes, and hypertension. 4.3.
On the other hand, three studies using Dex monotherapy (only one course of Dex; additional courses of Dex were administered only to nonresponders) 8 9 10 showed inferior SR incidence compared with that of PSL with borderline significance ( N = 437; RR, 0.80; 95% CI, 0.62–1.03; p = 0.08; Fig. 1b ).
Probiotic add-on treatment significantly reduced levels of von Willebrand factor (vWF) and increased levels of monocyte chemotactic protein-1 (MCP-1), brain-derived neurotrophic factor (BDNF), RANTES, and macrophage inflammatory protein-1 beta (MIP-1) beta with borderline significance ( P ≤ 0.08).
Nonetheless, the case group had lower mean ALT levels during chemotherapy, with borderline significance (mean ALT levels of 24.17 declined to 22.60 versus mean ALT levels of 22.70 increased to 26.33, P = .08).
We observed borderline significance in F/B ratio between men and women ( p = 0.08), although there were no differences in the F/B ratio between HbA1c groups in females ( p = 0.39), and in men ( p = 0.98).
The SMD in BMI and waist circumference reduction was not associated with statistical significance but approached borderline significance in favor of the ketogenic diet groups: p = 0.08 and p = 0.09, respectively ( Figure 4 ). 3.5.
Sensitivity analysis In the multinomial logistic regression analysis (Table 2 ), the variables associated with RFR were the following: (a) comparing donors with RFR versus those without RFR: baseline (pre-stimulation) mGFR, with borderline significance {odds ratio [OR] 1.06 [95% confidence interval (CI) 0.99–1.12], P = .08} and BMI [OR 1.20 (95% CI 1.03–1.40), P = .02]; (b) comparing those using RFR versus those without RFR: baseline (pre-stimulation) mGFR: [OR 1.24 (95% CI 1.12–1.38), P < .0001] and BMI was not significant.
However, this model did not reveal any statistically significant associations ( Table S5 ), except a borderline significance of antibiotic consumption with an incidence ratio of 0.99 [95%CI 0.97-1.00] ( p = 0.08). 3.2.
Then, we evaluated NRAS-mutated versus NRAS-WT (BRAF-mutated and WT/WT combined) and found a borderline significance in mean RFS after metastasectomy (NRAS-mutated versus NRAS-WT; 30 vs 53 months, p = 0.08) (Table 4 ).
Nonetheless, the case group had lower mean ALT values during the chemotherapy with borderline significance (22.60 versus 26.33, P = .08; Table 4 ).
Borderline significance was also found for less than high school education (mean difference = -2; p = .08).
In multivariable linear regression analysis (Table 3 ) with adjustment for the individual characteristics of age, sex, BMI, waist circumference, possible NAFLD, male–FPG interaction, female–HbA1c interaction, antihypertensive drug or statin use and FPG or HbA1c, neither HbA1c nor FPG were independently associated with any of the cardiometabolic risk factors analyzed, including HDL cholesterol ( P = 0.6), but the negative interaction between female sex and HbA1c with respect to HDL cholesterol was still apparent, albeit at borderline significance (Table 3 ; coefficient: −0.02, 95% CI −0.05 to 0.003 mmol/L, P = 0.08), whereas the positive interaction between male sex and FPG with respect to HDL cholesterol was still fully significant (Table 3 ; coefficient: 0.21, 95% CI 0.05–0.37 mmol/L, P = 0.009).
Although this result has borderline significance ( p = 0.08), it indicates that increased expression of miR-486 enhances tissue invasiveness.
Marital status was retained despite its borderline significance ( p = 0.08) due to its theoretical relevance to health-related behaviors.
Relationship between IL/cytokine levels and respiratory symptoms and diseases Subjects with morning cough in the past 12 months had lower levels of IL5 and IL10 with borderline significance ( P =0.08 and P =0.09, respectively; Table 2 ).
Despite the small number of cell lines tested here, we conclude that 74% of toxicity-modulating proteins in our screen appears to be different from the random sampling of proteins (borderline significance, p = 0.08 (Fischer's exact test)).
One analyte (FOSAA) was negatively associated with age, but with borderline significance ( p -value = 0.08).
However, when comparing all hospitalization days of oral intake regardless of which buspirone window, there is only borderline significance that oral intake is worse on days that buspirone was administered: t(85 degrees of freedom) = 1.43, p = 0.08.
Patients with vision better than log of minimum angle of resolution 1 and with hypertension improved less compared to those without hypertension, though with borderline significance (unadjusted OR = 0.608, confidence interval: 0.34–1.06, P = 0.08) [ Fig. 2 ].
In fact, the cut-off age was chosen arbitrarily, but lowering it to 14 years did not yield further significant differences between the age groups (except for a borderline significance of P=0.08 in Rmin improvement), keeping in mind that the overall number of eyes dropped to 24.
The presence of BRAF mutation had trended to correlate only with younger age of patients, with borderline significance (median, 51.5 vs 56.5 years for BRAF + vs BRAF −; p = .08) (Table 1 ).
Furthermore, a direct comparison of the K scores between negative and positive images was also significant, t (38) = −2.66, p = .01, Cohen's d = −0.84, while the difference between the two neutral conditions only revealed borderline significance, t (38) = −1.76, p = .08, Cohen's d = −0.55 (see Figure 2).
Second, elderly females had each of the six disabilities in higher percentages (with a borderline significance level [ p = 0.08] for difficulty remembering) than elderly males.
MCP-1 showed borderline significance on day 8 (p = 0.08) between groups, with subsequent tendency toward elevation by day 16 in the experimental group (p = 0.35).
However, a borderline significance was observed ( p = 0.08) when readmitted to ICU suggesting that the impact of PC on survival is not uniform but depends on their severity and the overall postoperative course.