“an observed trend”

Before this study, there was concern that cetuximab could even be worse than radiotherapy alone in older adults, based on an observed trend toward worse outcomes in patients older than 65 years. 31 This, coupled with the presumption that immunotherapy would likely improve outcomes, prompted the use of a 2:1 randomisation, ostensibly to limit exposure of patients in the control group to potentially less effective therapy.

However, an observed trend suggested a numerically higher incidence of I endpoint in the clopidogrel group at 180 days (2.8 % for clopidogrel group vs. 2.1 % for ticagrelor group; HR, 1.33; 95 % CI, 0.98–1.80; P = 0.07).

This research highlighted the importance of endosomes in signal modulation at different points during development, continuing an observed trend in the regulation of RTK signaling [ 64 ].

Although not statistically significant, there was an observed trend in which CAB + RPV Q8W had a numerically higher risk of resistance compared with all INSTI‐based STRs and CAB + RPV Q4W.

Observed trends An observed trend in all performance tests was that patients’ upper limb function seemed to decrease slightly from cessation of intervention to 6 months post intervention.

Despite an observed trend of decreasing yield (when moving from unsubstituted to aromatic thiosemicarbazide, see descriptions 1a–c in the Supplementary Materials ), the acylation products were isolated and characterized in all three cases.

[ 34 ], within the AMICS subgroup, an observed trend toward enhanced discrimination was noted.

We presume that such an observed trend may probably be because of the possible bias in the results due to husbandry and management procedures, the most important of which is the feed supply.

There was an observed trend between higher disease duration and activity and RLS.

An observed trend indicates a decrease in the lift-to-drag ratio with an increase in the angle of attack.

The light flicker–induced ratio of OEF was not significantly different between NC and NDR subjects, despite an observed trend of impaired vasodilatory response, suggesting a diminished light flicker–induced response in DO 2 .

There was an observed trend of phenotypic resistance against Norfloxacin, Ampicillin and Tetracycline among Gram‐negative bacteria (mostly Enterobacteria ).

Across all BMI groups, there is an observed trend that as BMI increased, the percentage of women with a self-reported PCOS diagnosis also increased (see Fig. 4 ).

Furthermore, in the context of thoracic myelopathy, there is an observed trend toward delayed diagnosis when compared with conditions such as lumbar spinal canal stenosis.

Although there were no significant differences between energy and carbohydrate intake and food security status, there was an observed trend where the energy and carbohydrate intake decreased as food insecurity worsened.

We followed up an observed trend.

Unlike in Western European countries, where there is an observed trend toward increased incidence rates of candidemia, our incidence rate did not significantly increase over the study period.

Discussion In this retrospective comparative analysis, treatment with tenecteplase was associated with an observed trend toward increased likelihood of achieving functional independence at 90 days compared with alteplase.

Furthermore, there was an observed trend that indicated an increased likelihood of hospital admission for patients with both COVID-19 and diabetes [ 29 ].

In contrast, there was an observed trend for negative correlations between total cored plaque score and Aβ pathologies (subpial pathology, diffuse plaques, CWPs); this was particularly evident in the PSEN1 post‐codon 200 group, and slightly evident for diffuse plaques and CWPs in the APP group (Figure 3A–D ). 3.3.4 Differences across cortical layers As reported above, we did not find evidence of total Aβ pathology scores differing between the sub‐groups.

Conversely, in dispersed cultured DRGs, there was an observed trend of increased expression for both Osmr and Il31ra after OSM stimulation ( Figures S2A, B ). 3.5.

Although not statistically significant, there was an observed trend for an increased prevalence of moderate–severe gingivitis with an increasing number of toothbrushes per day.

Despite an observed trend toward preferential directional positioning, this placement can be transient, influenced by the cell cycle or environmental modifications.

Notably, there was an observed trend of Black or African American populations experiencing higher overall crude rates in every region compared to all other races.

This is consistent with an observed trend of decreasing number of people who smoke in the Czech Republic, with comparable results in post-MONICA studies and NAUTA studies concluded regularly by National Institute of Public Health (SZÚ) [ 18 ].