“an increasing trend”

The administration rates of non-selective NSAIDs exhibited an increasing trend in the intraoperative phase (0.1% vs. 30.5%, P < 0.001) and POD 0 (2.4% vs. 26.8%, P < 0.001).

The majority (64.29%, 54/84) of the patients underwent laparotomy, and an increasing trend of minimally invasive surgical approaches (p<0.001) and fertility-sparing techniques (p<0.001) was observed.

Whereas agency terms in the antisemitic text showed no significant trend before the Holocaust, agency terms in the control text showed an increasing trend during this time, b 1 = 0.01, 95% CI [0.005, 0.011], SE = 0.001, t = 4.92, p < .001.

In addition, the tissue enzyme level of SRD5α2 exhibited an increasing trend ( P < 0.001), and the nuclear factor NF-κB p65 and the transforming growth factor TGF-β also showed a significant upward trend ( P < 0.001). 3.2 Metabolomics study 3.2.1 Metabolic profile analysis Metabolomic studies were conducted using the UHPLC-Q-Orbitrap HRMS technique.

Piecewise regression estimates provide no evidence of a time trend between 2000 and 2012 (PRR 1.00, 95% CI 0.99, 1.02; p = 0.99), whereas there was an increasing trend in TB prevalence of DS between 2013 and 2015 (PRR 1.16, 95% CI 1.07, 1.26; p < 0.001) and a decreasing trend between 2016 and 2021 (PRR = 0.94, 95% CI 0.92, 0.97; p < 0.001) ( Fig. 2 , Table 2 ).

The crude death rate of cancer in the six provinces of northwest China from 2013 to 2021 showed an increasing trend (AAPC = 3.96%, p < 0.001).The age-standardized mortality rate of cancer in six provinces in northwest China was overall stable from 2013 to 2021 (AAPC = − 0.13%, p = 0.928) but exhibited a decreasing trend from 2017 to 2021 (AAPC = − 5.64%, p = 0.047).

A change in the type of admission for colorectal patients was observed, with an increasing trend towards elective cases in the latter group (p=0.001).

The significant mean for each slope factor demonstrates that all participants experienced a decline in sleep duration (μ = − 0.236, p < 0.01) and an increasing trend in frailty (μ = 0.514, p < 0.001) over time.

Trends over time in carriage prevalence of Streptococcus pneumoniae serotypes Among the Sp-carriers based on Quellung-results, a decreasing trend (p < 0.001) in the proportion of non-PCV13-VTs (94.6%, 438/463 isolates in 2016 vs 96.9%, 594/613 isolates in 2016–2017 vs 89.7%, 599/668 isolates in 2017–2018) was accompanied by an increasing trend (p < 0.001) in the proportion of PCV13-non-PCV10-VTs (3 + 6A + 19A: 0.9%, 4/463 isolates in 2016 vs 1.6%, 10/613 isolates in 2016–2017 vs 7.8%, 52/668 isolates in 2017–2018; Figure 1 ).

The levels of triglyceride showed an increasing trend in a time-dependent manner ( P < 0.001) in all animals receiving the 1% high-cholesterol chow.

The number of cases increased from 7.69% in 2000 to 38.42% in 2018, showing an increasing trend (AAPC = 9.4; 95% CI 1.4−18.0, p < 0.001), with 25.4% underreporting.

IL-22 treatment even will lead to an increasing trend for body weight ( P < 0.001; Figure 1(d) ).

In Switzerland an increasing trend of testicular cancer has been observed over a period of 35 years with a growth of 1.4% every 2 years (95% CI: 0.7–2.0; p < 0.001).

The mean BMI at presentation showed an increasing trend over time; the linear regression association was statistically significant among type 1 DM ( P <0.001) ( Table 1 , figure 1 ).

Before the pandemic, there was a slight insignificant increasing trend in opioid poisonings that changed significantly after the pandemic (1.47 cases per month, p-value = 0.006, Table 3 ) and led to an increasing trend of 1.53 monthly cases during the pandemic (p-value < 0.001).

The only state showing an increasing trend was Santa Catarina, where a significant rise was identified among females (APC 9.03; 95%CI 6.49; 11.64; p=0.001) ( Table 2 ).

An increasing trend of dietary intakes of total energy, carbohydrate, cholesterol and protein was observed across increasing intakes of L-arginine ( P = 0.001); compared to the lowest tertile, those in the highest tertile of L-arginine had also lower intakes of total fats as well as saturated and unsaturated fats ( P = 0.001).

Reported pain was frequent across the years, affecting 70% of patients with an increasing trend ( p < 0.001).

Figure 3 indicates an increasing trend in the annual hospitalisation rate due to bronchiectasis exacerbations among patients with a higher incidence of CVD (p=0.001).

The concentrations of total ceramide and total FFA showed an increasing trend (P < 0.05) in women with PCOS, while the concentrations of LPG had a decreasing trend (P < 0.001).

The positive expectancies of cannabis use effects score measured among the participants demonstrated an increasing trend (T1: mean 6.41, SD 2.85; T2: mean 7.20, SD 2.93; T3: mean 7.96, SD 2.99; P <.001).

The prevalence of these infectious etiologies differed significantly across the groups, showing an increasing trend from the lowest to the highest quartiles (pneumonia: increasing from 38.95% in Q1 to 52.98% in Q4; sepsis: from 33.40% in Q1 to 46.91% in Q4, P<0.001).

Linear regression revealed an increasing trend of combined shoulder and elbow injuries (slope = $22.35 million/year, R 2 = 0.786, P < .001; Figure 1 ), elbow injuries (slope = $17.93 million/year, R 2 = 0.628, P = .006; Figure 2 ), and shoulder injuries (slope = $4.41 million/year, R 2 = 0.422, P = .042; Figure 3 ).

The prevalence of obesity in all age subgroups showed an increasing trend over time in boys as well as in girls (p<0.001).

However, when time was incorporated as a continuous variable in our analysis, there was an increasing trend in MMP-9 activities over time ( p = 0.001).