Model-derived risk scores were significantly higher in BTC than in non-cancer controls across cohorts and showed an increasing trend with advancing stage in the external validation set, suggesting an association with tumor burden.
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Temperature and precipitation have a certain regulating effect on CFI, both of which show an increasing trend first and then decreasing with the increase of factor value.
In TCGA, higher TMEM184A expression associated with larger primary tumours (T), distant metastasis (M) and more advanced clinical stage, with an increasing trend across N stage despite non-significance (Fig. 4 E).
Runoff erosion rates in all treatment groups showed an increasing trend with prolonged rainfall duration, though the magnitude of increase varied.
This study found that compared with the control (CK), the HCO 3 - content and sodium adsorption ratio (SAR) in the 0–10 cm and 10–20 cm soil layers were significantly reduced under organic fertilizer (T3) treatment, while they showed an increasing trend in the 20–30 cm soil layer.
In the present study, valeric acid showed an increasing trend in the migraine group, although the between-group difference did not reach statistical significance.
Areas showing an increasing trend in NEP constituted 5.3%, while those exhibiting a decreasing trend accounted for 7.5%.
Certain metabolites from the downstream LOX and CYP450 pathways of AA showed a significant decrease, while downstream products of the CYP pathway exhibited an increasing trend ( Figs. 3 N and S2J ).
All classes of antibiotics had a drop in DDD during 2020–2021, but showed an increasing trend in the following years ( Figure 3 (a)).
In older men, the leading causes were cardiovascular diseases and liver cirrhosis, whereas in women, cardiovascular diseases led by ischemic heart disease displayed an increasing trend over time.
Additionally, while ADP and AMP levels in the treatment group showed an increasing trend, their absolute concentrations remained lower than those in the control group, suggesting that cells accelerate ATP breakdown to sustain basic life activities under energy insufficiency-and this accelerated ATP consumption further exacerbates dysregulation of energy metabolism [ 35 ].
An increasing trend in the number of cases tested and JE detections was noted, alongside a shift in the age distribution towards younger populations.
However, FBW, PWG, SGR, and FE showed an increasing trend, but these increases were not statistically significant.
Although nitrite concentrations showed an increasing trend in the BWP groups, the observed level (approximately 10 μM) was not considered indicative of a major nitrosative contribution to toxicity under the present experimental conditions [ 35 , 36 ].
Furthermore, WC was larger in the high CHG index group, and WBC, HGB, and HCT also showed an increasing trend.
Conversely, patients with positive pathogenic results showed an increasing trend between 2015 and 2020 (APC = 23.61%, 95% CI: 15.40 to 32.41) (Table 1 ).
Prevalence of FA and An In WJSAAC-IV (2012) and WJSAAC-V (2022), the prevalence of food allergy (FA) was 3.6% and 4.9%, respectively, indicating an increasing trend over the past decade.
Conversely, three specific components (Cryo, Irradiated PCa, and Filtered & Irradiated RBCs) showed an increasing trend in demand over the study period ( Table 2 ).
Since the capacitance change (Δ C ) increases, the current output shows an increasing trend ( Figure 4 C).
Rhegmatogenous retinal detachment (RD) is a severe ocular condition whose incidence is reported between 10 to 17/100,000 cases per year with an increasing trend in the past decades. 1 – 4 Recurrent retinal detachment (Recurrent RD) develops in 18% to 22% of patients undergoing primary repair 5 – 7 and retains a guarded prognosis in a relevant proportion of affected patients, potentially leading to blindness. 8 Proliferative vitreoretinopathy (PVR) is the p
The EAPC was then derived using the formula: (2) Positive EAPC values, with 95% confidence intervals (CIs) excluding zero, indicated an increasing trend, while negative values indicated a decline.
Recent reports from EV-D68 outbreak in Europe in 2024 suggested an increasing trend of viral circulation among adults [ 21 ].
An increasing trend is observed in Maroni sector.
The results showed that, compared with native PGS, the molecular weight and particle size of DPGS decreased with increasing ultrasound time, while solubility and galactose content showed an increasing trend.
The absorbance showed an increasing trend with time in the interval of 2–8 min after the initiation of the reaction.