“an increasing trend”

Notably, there has been an increasing trend in the number of studies that have evaluated the application of artificial intelligence in dentistry in these years, which indicates an increasing interest in publishing articles of this type (as depicted in Fig. 2 ).

A study by Best et al 33 demonstrated both variability and an increasing trend in the use of dexamethasone for children hospitalized for asthma exacerbations among hospital sites.

In addition, IRF5 and IRF8, key members of the interferon regulatory factor family involved in microglial inflammatory regulation [ 75 , 76 ], showed an increasing trend in Csmd3 + microglia based on scRNA‐seq data.

Subsequently, the concentration of proteins in the bacterial extracellular content showed an increasing trend after treatment with different concentrations of Py‐27 (4 × MIC, 2 × MIC, and MIC), confirming the loss of cell membrane integrity (Figure 9D ).

Abstract In recent years, with the widespread participation in athletic activities, the incidence of anterior cruciate ligament (ACL) ruptures among adolescent populations has shown an increasing trend.

Lastly, although H&E staining of lung tissue sections revealed an increasing trend in severity of inflammation in Foxp3 PLXND1 KO mice compared to the PLXND1 fl/fl the result did not reach statistical significance (Figure 4G,H ).

Between 2002 and 2017, an increasing trend (APC: 1.81; 95%CI: 0.14 - 3.81; P -value: 0.04) was observed and between 2018 and 2023, a stationary trend was found again (APC: 0.24; 95%CI: -1.67 - 1.44; P -value: 0.64).

Racial distribution similarly exhibited an increasing trend in non-Hispanic White individuals within AISI groups, reaching 48.7% in Q4.

Both ASIR and ASDR exhibited an increasing trend across all age groups over 32 years.

[ 35 – 39 ] In Slovakia, two deaths related to HFRS were reported in the 1950s, [ 53 ] and 746 cases were documented between 2007 and 2023, indicating an increasing trend with two peaks observed in recent years.

The annual publication volume showed an increasing trend, with acceleration after 2015.

Introduction Periodontitis [ 1 ], a chronic inflammatory disease affecting 20–50% [ 2 ] of the global population and an increasing trend [ 3 ], imposes a substantial burden on oral health and systemic well-being.

An increasing trend of Nu with Reynolds number is clearly observed, reflecting the enhancement of convective heat transfer with increasing flow rate.

As expected, in our multiomics study, disease severity followed an increasing trend from SDC to UDC peaking at the pre-ACLF group, whose patients had higher rate of ascites and infections, higher serum bilirubin, INR, creatinine, ALT, leukocyte and neutrophil counts, and CRP, and lower hematocrit, mean arterial pressure, and serum levels of sodium and albumin (Supplementary Table 1 ).

In addition, based on the average relative abundances of the 25 most dominant genera in each cluster ( Figure 3A ), we found that unassigned Micrococcaceae showed an increasing trend in groups C1-C4 while Staphylococcus , Serratia , Enterococcus , and Lactococcus showed decreasing trends.

On the contrary, LPC in the kidneys of the HFD and HFD/STZ group showed a significant increase compared with the control, and demonstrated an increasing trend in the liver.

Bulk RNA-seq analysis of LES showed that the expression of Cd79a, Cd19 and other immunoglobulin-related proteins exhibited an increasing trend in Fam129c -mut mice compared to WT controls (Fig. 3A ).

16 , advancing the fuel injection timing results in an increasing trend in both cylinder pressure and combustion heat release rate under both 100% and 50% load conditions.

1A , except for the years 2018 to 2020, which were affected by hospital reforms and the COVID-19 pandemic, the number of new thyroid cancer cases has shown an increasing trend from 2008 to 2023.

In contrast to the aforementioned parameters, MCV, MCH, and RDW‐CV exhibited an increasing trend with age (Table 2 , Figure S1 ).

On the other hand, there was an increasing trend toward increased LRO risk in patients who carried more CMRFs than in those without any CMRF (aHR/CI: 1.35/1.02–1.78, 1.48/1.11–1.97, and 1.53/1.15–2.05 for 1, 2, and ≥ 3 CMRFs, respectively) (Table 2 and Figure 2C ). 3.4.

An increasing trend in the number of late syphilis cases was observed from 2020 to 2024 (Figure 3 ).

Regarding citations, an increasing trend was observed from 2015 onwards, with the peak being reached in publications in 2018 (Figure 1).

In CSF, ctDNA dynamics appeared to stratify by response outcome: patients with complete response/partial response (CR/PR) at both first assessment (at week 6) and best intracranial response showed low baseline ctDNA levels with a declining trend, whereas those with stable disease (SD) at both time points demonstrated relatively high baseline levels or an increasing trend ( Figure 4 C).

Unsupervised clustering (Mfuzz) revealed three trajectory patterns across increasing metabolic risk burden: 16 metabolites showed a consistently decreasing trend (cluster 1), 19 showed an increasing trend (cluster 2), and the remaining formed cluster 3 ( Figure 2 D).