“an increasing trend”

HDL cholesterol shows the least consistent findings where three studies reported an increasing trend, yet this was not statistically significant; one study reported a mild increase in HDL (+0.90 ± 0.12; p < 0.0001); and one study reported a slight reduction in HDL (55.6 ± 2.5 to 51.6 ± 2.2; p < 0.05).

An increasing trend in global health status from baseline was noted over 25 exposures ( p < 0.0001) (Figure S2 ).

The concentration of β2-MG showed an increasing trend with medication for any disease ( p = 0.03), history of OCE ( p = 0.03), and period of OCE ( p = 0.01), and eGFR and age ( p < 0.0001), whereas it exhibited a decreasing trend with smoking history ( p < 0.0001), history of OCE ( p < 0.0001), and period of OCE ( p < 0.0001).

The Cochran-Armitage trend test showed an increasing trend in infection rate with increased age in all four years’ national surveillance ( P <0.0001).

In the absence of BPs, vWF expression by the endothelial growth media stimulated pMSCs showed an increasing trend over the experimental period with a significant 4-fold up-regulation (p < 0.0001) in expression at the end of ten days.

Although the proportion of medication costs in outpatient medical costs immediately decreased 4.81 percentage points after the intervention, however it subsequently rose with an increasing trend of 0.28 percentage point per month ( p < 0.0001) (Table 2 ).

In figure 2 , changes in the total score of adherence to treatment were compared between the control and intervention groups, which indicated an increasing trend in the mean total score of the intervention group within the first, third, and sixth months, compared to the pre-intervention stage (P=0.0001).

Additionally, with the progression of the induction period, a decreasing trend in scleral fibers’ diameters was observed in the left eyes ( F = 31.85, P < 0.0001), while an increasing trend was noted in the right eyes ( F = 7.68, P = 0.0005).

CCK-8 assays revealed that cell viability showed an increasing trend at 4 mM MgSO 4 ( p < 0.0001; Figure 6a ).

Results There was an increasing trend in overall firearm injuries between 2010 and 2020 among adults in this large integrated healthcare system ( p < .0001), primarily driven by non-self-inflicted firearm injuries ( p < .0001).

In addition, we observed an increasing trend in terms of pre-diabetics along with increasing BMI, from 0 for BMI< 18.5 kg/m 2 to 63% for 35 ≤BMI < 39.9 kg/m 2 (P<0.0001).

The age-adjusted annual incidence ranged from 1.0 per million in 2004 and 2006 to 1.4 per million in 2013; there was an increasing trend in age-adjusted incidence over the entire period ( p <0.0001) but no significant increase during the second half (2010–2016, p = 0.08).

Moreover, the prevalence of subjects defined as being overweight/obese, having central obesity, and those with dyslipidaemia showed an increasing trend in all age groups (P-value<0.0001).

In terms of the infection site, multiple infections showed the highest gross medical costs with an increasing trend (rate = + $63.6 million/year, p < 0.0001) followed by respiratory infection (rate = + $65.0 million/year, p = 0.002).

Insulin sensitivity, resistance and secretion Homeostatic model assessment of insulin resistance was lowest in the NGT participants and presented an increasing trend in the five groups (NGT, P60, P90, P120, P150; P < 0.0001).

The Mann-Kendall trend test showed an increasing trend between the top-cited articles’ citation density and their published time ( P < 0.0001) (Fig. 3 ).

The fever clearance time (FCT) and asexual parasite clearance times (APCT) were, respectively, 36.5 ± 10.9 and 43.5 ± 11.8 hours, and there was an increasing trend of both FCT (F = 268.41, P < 0.0001) and APCT (F = 88.6, P < 0.0001) from 2007 to 2013.

The trend test also showed an increasing trend in the findings ( p < 0.0001).

In terms of the severity of SCI, there was a decreasing trend over time for AIS grade A (P = 0.0036) and grade C (P < 0.0001), while an increasing trend was observed for grade D (P < 0.0001).

Furthermore, the graphical analysis highlighted an increasing trend in the metabolically active viable cell population, dependent on the number of CAP applications ( p < 0.0001).

There were significant differences in mean systolic (SBP, mean±SD mmHg: 102±12, 108±11, 112±12, 116±12) and diastolic blood pressure (DBP, mean±SD mmHg: 62±10, 66±8, 68±8.9, 70±9) across the four BMI groups with an increasing trend (p-values<0.0001).

As shown in Figure 1 , UVM exhibited an increasing trend from 1975 to 2016, with an average annual percentage change (AAPC) of 2.6 (95% CI, 0.3, 4.9, p < 0.0001).

The absorbance measure of the IEC proteins was dose-dependent ( r = 0.994, P < 0.0001) and showed an increasing trend with increasing IEC protein coating concentration ( F = 397.007, P < 0.0001) (Figure 8 A).

Association between search activities of CKD, dialysis, kidney failure, and kidney transplant Globally, linear regression analysis indicated an increasing trend in monthly search activity for CKD ( y = 0.299 x + 13.29, R 2 = 0.937, p < .0001), dialysis ( y = 0.114 x + 59.38, R 2 = 0.548, p < .0001), kidney failure ( y = 0.128 x + 53.40, R 2 = 0.728, p < .0001), and kidney transplant ( y = 0.080 x + 39.35, R 2 = 0.262, p < .0001) ( Figure 2(A) ).

Patients showed an increasing trend for the prevalence of hepatic steatosis with fibrosis stage (Figure 1 (a), p = 0.0001).