Barely Significant
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“an increasing trend”

63,972 sentences · 63,972 papers · 107,686 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Introduction Crohn disease (CD) is a chronic gastrointestinal inflammatory disease, with an estimated incidence rate ranging from 0.3 to 12.7 new cases per 100,000 people in Europe 1 and showing an increasing trend in both adults and children. 2 , 3 Most cases are diagnosed during third and fourth decades of life although it may also affect children or older individuals. 1 It may involve any segment along the gastrointestinal tract, most commonly terminal ileum and colon.
However, on day 28, we observed an increasing trend in the relative abundance of Firmicutes , which could be explained by the effect of RMD, as indicated by previous research [ 43 , 44 ], Another possible factor is the production of lactate by Bifidobacterium longum , which can be utilized by members of Lachnospiraceae , thereby stimulating their proliferation [ 45 ].