“an increasing trend”

Furthermore, there was an increasing trend in annual incidences of repeat syphilis over 11 years ( β = 0.08, P < .001).

Age varied significantly among groups, showing an increasing trend with greater myopia severity (P < 0.001).

In addition, there was an increasing trend in number of tests ordered in the past year among pediatric ( P < 0.001, Supplementary Table S1 ) compared with adult clinicians .

Concurrently, UACR demonstrated an increasing trend in albuminuria across the quartiles (p < 0.001).

In addition, there was an increasing trend between the level of general health problems and PIU ( P <0.001).

Hypertension showed an increasing trend across groups, being highest in the Lower PhA×Elevated ECW/TBW Ratio group (68.4%, p < 0.001).

The use of oral 5-ASA alone showed an increasing trend, beginning at 18.9% preconception and rising consistently to 24.6% postpartum ( P < .001, Cochran’s Q = 16.056).

At both the 6th and 12th months, both the DS lens group and the SVS group showed an increasing trend in SE, with the SVS group exhibiting a significantly greater increase in SE compared with the DS lens group (p<0.001).

There was an increasing trend of more pain interfering with sleep reported in adults classified in higher GMFCS levels ( p <0.001).

The proportion of adenocarcinoma showed an increasing trend with staining intensity (57.6% in IHC 1 +, 73.5% in IHC 2 +, 87.1% in IHC 3 +; chi-square = 26.7, P < 0.001).

Moreover, our results showed an increasing trend in WC and BMI across the quartiles of non-HDL/HDL and TG/HDL (P-value < 0.001).

Through trend test analysis, the clozapine serum concentration showed an increasing trend with increasing drug dose ( p < 0.001), and the C/D ratio showed a decreasing trend with increasing daily drug dose ( p < 0.001) (Table 3 ).

An increasing trend of posterior lamellar techniques over the total of keratoplasties was found (p<0.001).

At the end of the study, quetiapine and fluoxetine were the second and third most commonly prescribed drugs, respectively, and both showed an increasing trend (both p < 0.001).

A stable trend was observed in Hong Kong ( P = 0.605) and the UK ( P = 0.155), while in the USA there was an increasing trend in price where the originator infliximab price increased at a rate of 5.14 USD/SU per quarter [( P < 0.001), Fig. 3 ; Table 2 ].

Kruskal–Wallis test shows an increasing trend of attrition score with increasing age (p-value <0.001).

Chi‐square analysis for trend shows an increasing trend with increasing RLS (chi‐square for trend = 16.490; p < 0.001).

Faecal pellets of high dose krill collected at 4 and 24 h on the last day of exposure clearly show an increasing trend of whole beads being egested over the final 24 h ( X 2 1 = 238, ( N = 24828), p < 0.001) (Fig. 2 ).

The median duration of delay in consultation was 18 (6,36) days, and 22,051 (56.65%) patients experienced a delay in consultation, with an increasing trend in the rate of delay in consultation in Shenyang City from 2015 to 2024 (χ 2 = 2235.857, P < 0.001).

Time from diagnosis to treatment initiation exceeded 60 days in >50% of cases in all age groups, with an increasing trend in women of 50–69 (APC = 1.27; p < 0.001) and \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\:\ge\:$$\end{document} 70 years of age (APC=1.83; p < 0.001).

Moreover, there was an increasing trend in the median (inter-quartile range) of GDF-15 concentrations from the patients with no DR, mild NPDR, moderate NPDR, to VTDR (P < 0.001 for trend) ( Figure 1 ).

D3 smokers showed an increasing trend between 2000 and 2010, following adjustment (GLF, P < 0.001; HSE, P = 0.04) with no significant trend found for D1 and D2.

We observe an increasing trend over time: from 12 therapeutic investigation publications in 2000 to 175 in 2021, ( ρ = 0.96, p < 0.001).

In these groups as well, sensitivity analyses excluding the year 2020 confirmed an increasing trend in sudden death–attributable mortality in both sexes [AAPC: +2.7% (95% CI: 1.8–4.0), p < 0.001 in men; and AAPC: +3.0% (95% CI: 2.0–4.5), p < 0.001 in women, respectively].

Similarly, there was an increasing trend in the total PQ base dosage administered (242.6 ± 79.7 vs. 265.7 ± 92.3 mg, P < 0.001), despite no significant differences in total weight-based PQ base dosage administered (3.38 ± 1.1 vs. 3.64 ± 1.3 mg/kg, P = 0.256) or the proportion of patients in the underdosing group (< 3.5 mg/kg; 296 [73.6%] vs. 167 [68.2%], P = 0.135] between the two periods.