“an increasing trend”

Regarding age distribution, the number of psychogenic AEFI cases in the age groups ≤ 6, 7–17, and ≥ 18 years were 20, 61, and 340, respectively, corresponding to a proportion rate of 0.02%(95% CI: 0.01–0.03), 0.07%(95% CI: 0.05–0.09), and 0.38%(95% CI: 0.34–0.42), respectively, showing an increasing trend with age ( P < 0.001).

The GnRH levels from NP-treated hypothalamus showed an increasing trend, especially significant in male 10 nM- and 100 nM-treated groups ( p <0.001) and female 1 nM-, 100 nM- and 1 μM-trated groups ( p <0.05, p <0.01 and p <0.05, respectively).

In total, these mild lesions contributed 57.9% (54.9, 61.0) to the total burden of CHD, with an increasing trend from 49.2% (43.4, 54.9) in 1970–74 to 65.3% (58.7, 71.7) in 2010–17 ( P < 0.001).

An increasing trend of risk of all-cause and heart disease mortality from group 1 to group 4 was observed ( P < 0.001 for trend; detailed statistical results are shown in Supplementary Table S1 ).

The averaged substitution rates for the latter emerging clades displayed an increasing trend along time, but showed no correlation with strain counts, MPDs and SI (linear regression model, β = 2.9 × 10 –5 , P < 0.001, Additional file 1 : Table S–D1; Fig. 1 c; Additional file 1 : Figs.

3.6 Empirical data: Stopover duration The analysis of the stopover duration of common species revealed an increasing trend at the rate of 1.39 days per year ( F 1,245 = 14.58, p < 0.001) (Figure 5e ).

PAR (%), after two decades of stability, showed an increasing trend over the period 1975-2011 (APC = 3.4, 95% CI: 2.8 to 4.0, p < 0.001), which was reversed in the more recent decade 2011-2021 (APC = -6.1, 95% CI: -9.6 to -2.5, p = 0.001), with PAR (%) decreasing from a historical high of 19.3% in 2012 to 8.6% in 2021.

Students receiving multiple interventions had higher scores on the pre-test as compared to those receiving a single intervention (P<0.001 for all comparisons among groups), and they demonstrated an increasing trend of awareness about gambling over time (P<0.001 for multiple interventions; P = 0.538 for single intervention).

The ELISA found that the concentrations of M1-related factors in the hematoma fluid significantly differed among the homogeneous type, laminar type, separated type, and trabecular type, exhibiting an increasing trend ( P < 0.001, Fig. 2 D), while the concentrations of M2-related factors showed the decreasing trend ( P < 0.001, Fig. 2 E).

Risk Factor Analysis of 5-Year Survival after Surgery The 5-year overall survival (OS) of all patients was 69.3%, and the mortality rate showed an increasing trend according to the stage ( p < 0.001).

Hypertension showed an increasing trend across groups, being highest in the Lower PhA×Elevated ECW/TBW Ratio group (68.4%, p < 0.001).

We observe an increasing trend over time: from 12 therapeutic investigation publications in 2000 to 175 in 2021, ( ρ = 0.96, p < 0.001).

Through trend test analysis, the clozapine serum concentration showed an increasing trend with increasing drug dose ( p < 0.001), and the C/D ratio showed a decreasing trend with increasing daily drug dose ( p < 0.001) (Table 3 ).

An analysis using the Mann–Kendall Trend Test identified an increasing trend from 6 am to 6 pm ( p -value < 0.001) and a decreasing trend from 6 pm to 6 am ( p -value < 0.001).

Furthermore, Ln (VEGF) showed an increasing trend with elevated HbA1c levels and UACR after adjusting for age and BMI in both the genders (all P < 0.001) ( Figure 2 ).

We observed an increasing trend in discontinuation rates from 2004 to 2022 (5% increase [95% CI, 3%-7%] per year) for haloperidol users (adjusted hazard ratio, 1.05 [1.03-1.07]; P < .001) but not for atypical APM users (1.00 [0.99-1.01]; P = .67).

In these groups as well, sensitivity analyses excluding the year 2020 confirmed an increasing trend in sudden death–attributable mortality in both sexes [AAPC: +2.7% (95% CI: 1.8–4.0), p < 0.001 in men; and AAPC: +3.0% (95% CI: 2.0–4.5), p < 0.001 in women, respectively].

The risk factors were the years of being a carpet weaver (Pearson's correlation coefficient = 0.33), level of education (the number of pain sites tended to decrease with higher level of education, p < 0.001), age (the number of painful sites showed an increasing trend with ageing, p < 0.001), physical loading at work (most of the painful anatomical sites were reported by the participants who had the highest physical loading at work, p < 0.001), time pressure ( p < 0.001), lack of support ( p < 0.001), and job dissatisfaction ( p = 0.001).

Regarding SD clusters, we found an increasing trend in ORx and OSRx average within 60 min just before SD clusters, as seen in the positive slopes derived from the fitted linear mixed-effects model (0.0013 [ p = 0.001] for ORx and 0.0009 [ p = 0.0001] for OSRx, respectively; Table 2 ) We also found a decreasing trend in ORx within 60 min just after SD clusters (− 0.0008, p = 0.0288) but no significant trend in OSRx post-SD clusters.

Across the different RC subgroups, there was an increasing trend in maximum cIMT ( P < 0.001) as RC levels increased within quartiles.

An increasing trend ( p < 0.001) was observed in the frequency of medical attendance during the study with the lowest frequency being observed in 2011 (average: 10.6; standard deviation: 2.8) and the highest frequency being observed in 2017 (25.5 ± 4.1).

Biochemical Parameters in Serum As shown in Table 4 , there was an increasing trend of activities of GOT and GPT with the increasing proportion of LQBFM combined with 0.50% CAs; the lowest values were both found in the LQBFM20+CAs group ( p < 0.001).

There was an increasing trend of more pain interfering with sleep reported in adults classified in higher GMFCS levels ( p <0.001).

coccoides , Roseburia , and Bacteroides , showed an increasing trend in AkhaCR (coordinate = 1.56, p < 0.001), while grain consumption was lower ( r = −0.53, p < 0.001).

MVC An increasing trend in MVC level were identified in both the case group and the control group in the first 14 days after the operation (the case group: F=94.320, P <0.001; the control group: F=52.440, P <0.001).