“an important trend”

An analysis of these reports highlights an important trend: the best visual acuity results come from the study with the greatest mean number of treatments and closest followup, whereas the poorest outcomes were observed in the study with the lowest mean number of treatments and office visits.

In summary, this study highlights an important trend in obesity-associated kidney stone prevalence but would benefit from methodological refinements to fully capture the complexity of obesity-related kidney stone pathophysiology.

When one looks at mortality trends during Wave 1 (Supplemental Table 2, Overall in-hospital deaths) across the hospital quartiles, it is not clear that there is an important trend or difference.

Moreover, we observed an important trend toward HCC diagnosed at earlier stages in the recent period.

Fig 3 also shows an important trend in terms of accuracy across the number of predictors.

Therefore, the combined model of disease and syndrome has become an important trend in the development of animal models of TCM treatment of KOA.

An important trend towards an increased number of online full-text views and downloads was observed.

An important trend is that hybrid systems enhance pretrained LLMs with external knowledge bases or retrieval modules to surmount the limitations of static training corpora.

We observed an important trend in the use of rolled quartz blocks, rather than cobbles and/or pebbles, which may be related to the intention of exploiting flatter and angular cortical surfaces—the cortical surface of cobbles and pebbles being more rounded.

However, due to the high cost of hardware equipment and the limitation of imaging technology in a specific situation, obtaining high-resolution medical images by super-resolution has been an important trend [ 6 ].

Thus, computer-aided diagnosis (CAD) has become theoretically and practically significant as an important trend in medical science.

The development of interpretable models is an important trend in bioinformatics [ 18 , 19 ].

The cost of sequencing has been dramatically reduced, which provides a solid technical basis for obtaining nuclear gene data of multiple species and will make it an important trend to combine a large number of genes and even whole genome data to study the phylogenetic relationships of angiosperms.

Design and Implementation The development of monitoring and measurement systems in the industrial sector, based on Internet of Things (IoT) hardware and software technology, is an important trend.

An important trend is the use of 13 C labelling for measuring fluxes (Zamboni et al. 2009 ), as well as the integration of experimental metabolomics with the genome-wide metabolic networks that are becoming available (Herrgård et al. 2008 ; Swainston et al. 2016 ; Thiele et al. 2013 ).

On the other hand, an important trend in the development of new materials is towards being lightweight, ultrathin, and flexible; the combination of different materials to obtain superior properties in multifunctional devices being necessary.

However, the separate analysis of the four pre-pandemic cohorts revealed an important trend: Since 2015/16, the achievement gap between immigrant and non-immigrant students seems to have widened each year with a slight decrease from 2017/18 to 2018/19 (see Table 3 ).

(3) Immunotherapy: With the widespread application of PD-1/PD-L1 inhibitors, research on immunotherapy for NSCLC has become an important trend, and the frequent occurrence of related keywords reflects researchers’ emphasis on predicting the efficacy of immunotherapy and exploring its mechanisms.

Keywords Enrichment design Subgroup analysis Overall type I error Power pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY-NC-ND 1 Background An important trend in treatment paradigm is personalized medicine, which is aimed to match patients to the most beneficial treatments.

The observed global decline in the prevalence of unintended pregnancies is an important trend with significant implications for public health, sexual and reproductive health and rights (SRHR), gender equality, and family well-being [ 9 , 12 ].

Studies have found, for example, an obvious trend of population shrinkage in less-developed regions such as Ireland and Estonia, which may become an important trend in regional demographic evolution for a long time to come, seriously threatening sustainable regional economic and social development [ 43 ].

This is an important trend in the future of teaching and learning.

Holistic medicine under the guidance of TCM principles is an important trend in medical development, whose framework is illustrated in a 4C+T diagram.

The increase of the photosynthesis efficiency has indeed been an important trend in buckwheat breeding since the middle of the 20th century.

This is an important trend in the field of collective motion as we move from a theoretical basis, centred around simulation studies, to a more data-driven approach.