Barely Significant
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“an important trend”

1,053 sentences · 1,053 papers · 1,736 search hits before verification · confirmed specimen

Sighted at

p=0.066

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

In vitro the 5-HT transporter, a critical element in neuronal 5-HT uptake, appeared specially upregulated with the poly(I:C) treatment and showed an important trend to increase in the hippocampal culture when costimulated with IFN-α, which may support the idea that the deregulation of 5-HT biosynthesis and metabolism may be involved in the development of this depression type.
Combined locoregional and systemic antitumor treatment in neoadjuvant therapy As both local therapies (vascular intervention, radiotherapy) and systemic antitumor therapies (molecular targeted drug treatment, ICI treatment) have their own therapeutic advantages and different antitumor mechanisms, attempting to combine therapeutic approaches to explore potential synergistic effects to improve patient survival is currently an important trend in the treatment of HCC (Table 3 ).