Barely Significant
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“an important trend”

1,053 sentences · 1,053 papers · 1,736 search hits before verification · confirmed specimen

Sighted at

p=0.066

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

INTRODUCTION Compared with traditional serial robot, the parallel one, with large stiffness, superior carrying capacity, minor error and high accuracy, etc., has recently become a research hotspot in academia and been extensively applied in automobile, aviation, medical machinery and other fields, which has become an important trend in the development of parallel kinematic machines [ 1 ].
The only ranodmized clinical trial (RCT) comparing the 2 devices is the PROTECT II trial, which showed overlapping safety profiles with an important trend for reduced MACE rate at 90 days and lower hypotensive events in 3-vessel disease. 9 Large subsequent registries offered conflicting results: from the same large database, a nonmatched comparison showed higher rates of death and bleeding in the Impella group, while a propensity-adjusted analysis demonstrated lower rates of mortality, myocardial infarction, and CS with Impella compared to IaoBP. 170 , 171 In contrast to ECMO, which provides full cardiopulmonary support, Impella is less invasive, easier to deploy, and associated with lower complication rates in the CHIP population.
A recent study showed that the HLA matched status changed in 29% of pairs after ultra-high resolution (UHR) HLA typing using Pacific Biosciences Single Molecule Real-Time sequencing (Menlo Park, CA, USA), and had significant improved clinic benefit ( 32 ), demonstrating that allele level typing (or all field typing) using NGS or other technologies might be an important trend in the field of HSCT.