Barely Significant
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“an apparent trend”

710 sentences · 710 papers · 2,363 search hits before verification · confirmed specimen

Sighted at

p=0.286

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

By contrast, although dalcetrapib has little overall effect on LDL cholesterol, there was an apparent trend towards a slightly larger reduction in LDL cholesterol among those with the rs1967309 AA genotype in dal-OUTCOMES. 6 Figure 2 shows the observed effects of CETP inhibitor therapy on major vascular events by ADCY9 genotype in the original hypothesis-generating dal-OUTCOMES trial in which there was a 39% (95% CI, 8%–59%) proportional reduction with dalcetrapib in individuals with rs1967309 AA genotypes compared with a 27% (95% CI, 2%–58%) proportional increase in those with GG genotypes, yielding a significant interaction (interaction P add =0.001, interaction P geno =0.006).