“an apparent trend”

We observed an apparent trend of strengthening of the chemopreventive effect associated with increased NSAID use during the post-trial period (Additional file 1 : Table S4).

While there is an apparent trend (the WCA decreasing with increasing oxygen content), the results are scattered significantly.

The three clusters were characterised by a different prevalence of musculoskeletal and renal activity, as well as use of immunosuppressants, with an apparent trend across clusters from the lowest prevalence in DORIS remission-enriched cluster 1, to intermediate prevalence in the mixed cluster 2, and the highest prevalence in cluster 3 that comprised the lowest proportion of DORIS remitters, as summarised in table 2 .

In FST, although there was an apparent trend of increased immobility time in rmCHI mice compared to control mice at both 30 and 60 days post-injury, no statistical significance was found ( Fig. 3B ).

However, despite an apparent trend, our upregulated X-linked genes did not contain a significantly higher proportion of genes which code for proteins in complexes when compared to non-upregulated X-linked genes (Supplementary Fig. 2k ).

Using this analysis a single major sub-group was observed (highlighted by an orange circle) reflecting an apparent trend for sequences of the same geographic region to be more closely related (Figure 4A, B ).

Although the increasing interest in hybrid polymers with germanium and tin confirms an apparent trend toward the heavier elements, reports on analogues of lead, the heaviest stable Group 14 element, are still lacking.

However, an apparent trend towards statistical significance was detectable ( Figure 2(d) ). 3.3.

An apparent trend is that charged residues are favorable in the affinity mature sequences while aromatic residues are disfavored.

On the other hand, after 24 h of incubation with BB-Cl-amidine, there was an apparent trend towards induction of LDH release in a concentration-dependent manner, while the combination of specific inhibitors still had no effect ( Figure 5E ).

There was an apparent trend of the significantly increased IL-12p40 and IL-10 production in samples from individuals with rs414171 TT genotype compared to carriers of the AA+AT genotypes.

The onset of afferent firing was variable, commencing 87 to 288 ms after the start of current injections and 20 to 9120 ms after the start of depolarizations, with an apparent trend toward reduced number of APs toward the end of the stimulus ( Fig. 4F ).

An apparent trend towards an increased proportion of Beijing strains in younger patients seen overall ( Table 1 ) is attributable to the higher proportion of immigrants in younger age groups.

Although there was an apparent trend toward lower sPAP in the acetazolamide group at high altitude, apart from not being statistically significant, these subtle changes (−2.1 ([95% CI, −4.4 to 0.3] mm Hg)) appear unlikely to be clinically relevant nor sufficient in preventing high‐altitude pulmonary edema.

Neutropenia is the only grade ≥3 AE showing an apparent trend towards increasing from Q1 to Q4 in PFS.

Moreover, with the increase in pulmonary arterial pressure and grading of heart function classification in the pulmonary heart disease group, plasma BNP and platelet-associated indices showed an apparent trend.

This is consistent with these same samples also having Al 2 O 3 contents > 5.5 wt% and an apparent trend towards crustal compositions in Fig. 4 E.

Individual responses for ad libitum energy intake (Figure 2 ) did, however, provide evidence of what appears to be an apparent trend toward compensatory increase in energy intake in 57.1% (n = 8) of subjects in EX but only14.3% (n = 2) of subjects in EXFS.

The increase in heart rate showed an apparent trend towards a relationship with the MPH dose [ 31 ].

Although none of the changes (i.e., after either 1 or 5 days of optical defocus) proved to be statistically significant for either strain, curiously over the time frame of this study only the EH strain showed an apparent trend of increased axial elongation after 5 days of optical defocus imposed with negative lenses.

With the spindle size of CPA-40Z, an apparent trend of these profile curves is that the viscosity of samples decreases sharply with an increase in the shear rate.

The findings countered initial expectations that aquacultures would be significant contributors to nitrogen pollution in the canals ( Ferreira et al., 2015 ).There is an apparent trend of reduced nitrogen pollution attenuation with intensification of the aquaculture practice, as would be expected from the reported fertilizer and feed inputs of the semi-intensive and intensive aquacultures, respectively ( Table 1 ).

All the cultures had a reduction ( p = 0.038, two-way ANOVA) in the SQDG (18:3/16:0) content after 48 h of growth as compared to the content after 24 h of growth, with an apparent trend of the content in the B culture being higher than in the other cultures (although only significantly different between the B and G cultures as indicated above).

More importantly, the cells showed an apparent trend of recovery after 72 ​h only in the case of SN38, providing another piece of evidence of a slower release and, possibly, a persisting effect of the drug when loaded on CDs ( Fig. 4i–n, 4o-r, 4 s). 3.3 Cell cycle monitoring Encouraged by the cytotoxic effect of the CD-SN38 hybrid material, the mechanism of cytotoxicity was investigated via the analysis of the cell cycle.

Based on the risk-adjusted analysis, we witnessed an apparent trend toward increased OS with FEDR, but the observed differences did not achieve statistical significance (HR [95% CI]: 0.6 [0.3–1.2]; P =0.1466).