“a worrying trend”

WHAT IS KNOWN ALREADY The ART success rate is ∼30%, with a worrying trend of increasing female age correlating with considerably worse results.

This is a worrying trend especially considering that the lack of physical activity is a common phenomenon in Saudi Arabia, being as high as 79% in the population we studied and 96% in the Saudi Coronary Artery Disease registry. 17 NAFLD has been shown in various studies to be independently associated with type 2 diabetes, low HDL cholesterol, high triglycerides, and insulin resistance. 9 , 13 , 15 , 16 These factors were also reflected in our study.

This is the first report of bla CTX-M-15 in UK river waters and represents a worrying trend as this gene is the most common ESBL in E. coli and Klebsiella spp . causing clinical disease. 4 Novel hosts were isolated across the Gammaproteobacteria, including Citrobacter braakii , A. media and P. fluorescens , none of which has previously been reported as a carrier of bla CTX-M-15 .

Amphibians are also the most threatened among terrestrial vertebrates, with a worrying trend of increased risk of extinction for newly discovered species, due to restricted ranges, small population sizes and impact from human activities 7 .

This is a worrying trend.

This is a worrying trend since international research depends on the national research and extension systems for the delivery and dissemination of their technologies and the sustainability of research for development (R-for-D, also often abbreviated as R4D) requires strong national systems.

Turning our gaze to China, a nation of over 1.4 billion people, the China Cardiovascular Health and Disease Report 2023 [ 5 ] reveals a worrying trend.

There has been in recent decades a worrying trend of decreasing Neurosurgical Residency operative numbers observed.

This is a worrying trend since the two health professionals interact during the care of patients.

The “indoorisation” of society is a worrying trend for human health for three reasons; firstly there is evidence associating time spent outdoors with improved outcomes for health and wellbeing; and secondly, time spent indoors is negatively associated with a number of health issues [ 10 ].

Both 11–14 and 15–17 year-olds logged multiple energy drink ads, a worrying trend given the established health risks of these products during adolescence ( 54 ).

This is a worrying trend which is possibly due to a combination of diabetes disease progression with time, and a lack of compliance and adherence with the treatment and lifestyle changes [ 54 , 56 – 58 ].

However, the increasing prevalence of physical inactivity among children has become a worrying trend, contributing significantly to the rise in childhood obesity [ 20 , 21 ].

A study conducted in Nigeria among health care workers found that approximately 85% believed all children with sore throat should be treated with antibiotics. 5 Furthermore, a study conducted among the general population in Saudi Arabia found nearly half of the participants believed antibiotics are helpful in treating sore throat. 15 While this shows basic awareness that bacterial infections require antibiotics, it also portrays a worrying trend of overprescription or self-medication especially in places where use of antibiotics is readily accessible over the counter, 19 which in turn can lead to the rise of resistant bacterial pathogens. 20 Addressing this issue requires joint efforts, particularly from governments and policy makers.

This metabolic disorder demonstrates a worrying trend of increasing incidence among younger individuals and serves as a major risk factor for various chronic conditions, including hypertension, fatty liver disease, cirrhosis, peripheral vascular diseases, ischemic cerebrovascular diseases, and pancreatitis ( 216 , 217 ).

Increasing caesarean section rates are a worrying trend that will have consequences for preterm birth rates if not addressed appropriately [ 75 ].

Studies indicate a worrying trend of declining self-esteem among this demographic, a crucial aspect of adolescent development that influences future mental health outcomes.

Can he still be considered an expert on the topic of forensics and profiling? Or was he more like a pseudo-expert all along? If experts could be reliably recognized as such, there would be no discussion about a current “crisis of expertise.” Yet, some have noted a worrying trend in our current intellectual environment: actual experts are sometimes ignored and dismissed, while non-experts tend to pose as and take the place of genuine experts ( Nichols, 2017 ; Eyal, 2019 ).

The increased HIV seroprevalence in older women and men may represent a cohort effect (i.e., the higher prevalence in younger women in the 1997 survey are now reflected in the cohort almost 10 years older), or could alternatively demonstrate a worrying trend towards increased HIV seroconversion in this age group.

Assuming the increased mental healthcare expenditure we found among young adults in the Dutch context is linked to poorer mental health in these generations, this is a worrying trend.

Currently diabetes affects almost half a billion people with a worrying trend in the next future [ 2 ].

Consultations gave experts the opportunity to highlight a worrying trend toward an increasing number of young Canadians being hospitalised for acute alcohol poisoning.

Globally, tuberculosis is the most common opportunistic infection affecting people living with HIV infection and AIDS (PLWHA), a worrying trend for a treatable and curable illness [ 3 ].

Antibiotic resistance patterns in our study reveal a worrying trend, with higher resistance rates compared to other international studies.

Discussion In recent years we have observed a worrying trend of increased occurrence of OSCC in young Zambian adults.