In line with our above reported analysis the corresponding effect in pMTG was less pronounced as revealed by a trend toward significance of this interaction (see Table 2 for the respective F and P values).
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“a trend toward significance”
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A p-value of ≤0.05 was considered statistically significant, with p-values of ≤0.10 taken as a trend toward significance. 3.
A p -value of <0.05 was considered to be statistically significant, whereas a value between 0.05 and <0.10 was considered to be a trend toward significance.
We observed that the P value for PVR was 0.063, indicating a trend toward significance.
Significant cocaine–CPP potentiation was obtained at the U50,488 dose of 5 mg/kg ( n =12–21; one-way ANOVA; F 3, 68 =3.09, p <0328; Dunnet's post hoc U50,488–5 mg/kg ( n =21) vs saline ( n =21), p <0.05), but was absent at 2.5 and 10 mg/kg U50,488 ( p >0.05), although there was a trend toward significance at 10 mg/kg U50,488 ( Figure 3c ).
However, this association was not statistically significant in female, although there was a trend toward significance in the male sample ( p value: 0.051).
For the anxiety dimension, the results were non-significant ( r = 0.271, N = 48, p = 0.06), but only a trend toward significance showing that participants who were high on the anxiety dimension were also high on the free factor.
LOCM is a risk factor for nephrotoxicity in patients with a stable eGFR <30 mL/min/1.73 m 2 ; there was a trend toward significance at eGFR of 30–44 mL/min/1.73 m 2 .
In that line, enhanced IgG level against latent protein EBNA-1 in MS patients was significantly associated with risk alleles of single nucleotide polymorphism within SOX8, MYB, CARD11, as well as a trend toward significance for HLA-DRB1 * 1501 (Kreft et al., 2017).
A trend toward significance indicates a need for large-scale multicenter studies for prospective verification.
Taken together, we observe a trend toward significance with an HSD3B7 variant rs9938550 to PD in a Chinese Han population while A allele of it is associated with a decreased risk of LOPD.
Additionally, due to the exploratory nature of the study, p -values ≤ 0.10 are considered indicative of a trend toward significance.
iron repletion on reduction of the primary endpoint (RR = 0.71; 95% CI 0.57–0.87, p = 0.001) compared to patients with non-ischemic heart disease (RR = 0.97; 95% CI 0.75–1.26, p = 0.83) as p for interaction of 0.06 showed a trend toward significance (Fig.
Regarding NYHA functional classes, in addition to class IV, class III (OR 2.88; 95% CI 1.68–4.97; p < 0.01) reached statistical significance in long-term prediction, while class II (OR 1.70; 95% CI 1.01–2.88; p = 0.05) showed a trend toward significance without fully reaching it.
Biomarkers were not different across racial/ethnic subgroups (p = 0.12 for cortisol; p = 0.82 for epinephrine; p = 0.96 for norepinephrine; p = 0.60 for composite biomarker index), although DHEA-S showed a trend toward significance: median 49 μg/dL (IQR: 32–77) among non-Hispanic Black women, median 57 μg/dL (IQR: 46–64) among non-Hispanic white women, median 119 μg/dL (IQR: 75–178) among Hispanic women, and median 64 μg/dL (IQR: 30–92) among multiracial or American Indian/Alaska Native women (p = 0.064).
Moreover, after adjustment for prognostic risk classification, which incorporates disease stage, MYCN status, and age at diagnosis, thereby partially addressing the constraints imposed by parsimonious modeling, the prognostic relevance of B7-H3 was further attenuated, losing even a trend toward significance.
Neutrophil count showed a trend toward significance but did not reach statistical significance ( p = 0.089).
While there was no significance to the stratification of patient outcomes based on treatment type, likely due to this analysis being underpowered to detect this difference, there was a trend toward significance with the GKS as a boost after surgery or as salvage after surgery being associated with longer survival times as compared to the other treatment types.
The model × prompt interaction showed a trend toward significance but did not reach the conventional threshold.
Some of the included studies were also limited by their sample size, 15 , 17 , 21 as their results showed a trend toward significance in favor of treatment with systemic chemotherapy combined with CRS‐HIPEC.
This study noted differences on the firm surface eyes open, which utilizes all three inputs (visual, vestibular and somatosensory) and a trend toward significance on the firm surface eyes closed, which utilizes vestibular and somatosensory input.
The JAK2V617F allele burden was also inversely related to C30 methylation, and a trend toward significance was appreciated with an inverse relationship to JAK2V617F allele burden.
For results reaching statistical significance or showing a trend toward significance, the effect size was calculated using Cohen’s d or the r coefficient, respectively.
Given that the effect size for RPC VD difference between the groups was moderate (hedges g = 0.72) and the microcapillary VD showed a trend toward significance, the lack of statistical significance may be attributed partly to our small sample size.
In contrast to YM, the correlations of SWV with the UPDRS total score ( r = 0.197, p = 0.051) and male sex ( r = 0.194, p = 0.053) showed a trend toward significance but did not reach the conventional statistical threshold.