There was a strong trend toward a higher percentage of healed patients (78.4% vs. 55.7% and 65.5%; p = 0.068) over a shorter duration (13.7 vs. 16.5 and 20.3 weeks; p = 0.055) in the R group, as well.
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The SNP309G allele was significantly associated with the presence of wild type TP53 (p = 0.047) and showed a strong trend towards increased MDM2 protein levels (p = 0.068).
In multivariate analysis of influence of immunohistochemical markers on EFS and OS, BCL2 was the only significant factor, while gal-3 showed a strong trend (p=0.068 for EFS and 0.093 for OS).
4.24 ± 0.23 μm 2 ; p<0.001), with a strong trend for the cell area in Apom -/- to be larger than in WT mice (5.80 ± 0.37 vs. 4.78 ± 0.24 μm 2 ; p=0.068; Figure 2d ).
TP53 mutations were negative predictive in both variant subgroups ( n = 30; P = 0.001) with a strong trend in variant 1 [2.6 month (95% CI: 0.0–10.9) versus 15.9 months (95% CI: 1.4–30.6); P = 0.068] and reaching statistical significance in variant 3a/b ( P = 0.022).
There are no differences between the different alloys; but there is a strong trend ( p = 0.068), which is consistent with the fact that for implant A it was ( p = 0.025) and not for implant B ( p = 0.178), showing a greater fit in Ti frameworks.
On the other hand, the pan IR700 + tra IR700 with NIR light demonstrated a strong trend towards greater tumor growth inhibition on Day 28 compared to the tra IR700 with NIR light group ( p = 0 . 0687 ; Mann-Whitney U test).
In multivariable analysis, only +LN was significantly associated with poorer FFDM (hazard ratio 4.6, p = 0.0015) though there was a strong trend with elevated CAIX expression (p = 0.069).
The following variables were associated with performance in univariate analysis: IPO price ( P < 0.001), time from IPO ( P < 0.001), number of drug programs ( P = 0.019), and academic funding ( P = 0.00013), with a strong trend for diverse pipelines ( P = 0.069).
Patients relapsing after third-line or later line of therapy had significantly shorter PFS (p = 0.001) and showed a strong trend to lower OS (p = 0.069).
There were similar results for the BF, with the low riser height resulting in greatest desaturation and strongest EMG signals (indicated by a strong trend in the effect of riser height ( p = 0.069) and a large effect size (ηp 2 = 0.14) over all gradients.
Moreover, in patients with early blast persistence, there was a strong trend towards a higher risk of non-relapse mortality, even in the presence of other risk factors (CS-HR=1.4, P =0.069) ( Table 2 ).
In support of our genetic results, we found that overexpression of LRRK2 IT led to a significant enhancement of pMad accumulation in the nuclei of glia surrounding DA neurons but not in DA neurons themselves ( Figures 5L–5N ). Similarly, we found that pMad accumulation in glial cells showed a strong trend toward enhancement (15% increase in mean pMad fluorescence intensity; p = 0.069) as a result of exposure to paraquat.
In addition, animals administered 5.0 g/kg ethanol during adolescence were significantly impaired in behavioral flexibility during CS 5 compared to animals administered 3.0 g/kg ethanol during adolescence ( p = 0.0389), and a strong trend in the data revealed an impairment compared to the control animals ( p = 0.069).
a strong trendgold
We observed a strong trend toward reduced tau pathology in the contralateral hippocampus of DMR7- and SKT82-treated mice compared to their respective IgG1 and IgG2b controls, although this did not quite reach statistical significance using two-tailed unpaired Student’s t-tests ( p = 0.069 and 0.077, respectively).
A further western blot analysis clearly illustrated a reduction in 5G2 (60%, p < 0.0001) and a strong trend for reduction in 1G11 (32%, p = 0.069) cellular retention in the T21 KD cells in comparison to their respective naive cells (two-way ANOVA: treatment: p < 0.0001, T21 expression: p < 0.0001, and treatment × T21 interaction: p = 0.0004, Figures S3D – S3F ).
We similarly found that TDP-43 depletion in iPSC-MNs corresponds with a strong trend ( P = 0.069) toward increased tau S262 phosphorylation ( Supplemental Figure 10A ).
In the present study, we found a statistically significant association between pretreatment NLR and OS using a cutoff value of ≥2 and a strong trend toward association with a cutoff value of ≥5 ( p = 0.069).
Dense adhesions showed a strong trend (p=0.069).
Group comparison of gray matter volume (GMV) No significant group difference in a voxel-by-voxel whole brain group comparison using TIV, IQ and age as control variables could be found, but a strong trend could be determined in the total GMV ( t (52) = 1.854; p = 0.069, Table 1 ).
The Nutrient Mobilization module was significantly correlated with AP (r = 0.493, p = 0.039) and showed a strong trend of association with NO 3 − -N (r = 0.663, p = 0.069).
Treating each sputum sample independently, we found a strong trend between PCA abundance and Fe(II) % (ρ = 0.185, P = 0.069), yet no correlation between PYO abundance and Fe(II) % (ρ = 0.042, P = 0.67) ( Fig. 2B and C ).
Hemisphere-specific N170 and N270 amplitude modulations were assessed using a three-factorial rANOVA across factors “component,” “hemifield,” and “match.” This analysis confirmed a location bias for the N170 within the left hemisphere and the N270 within the right hemisphere, respectively, as a strong trend toward an interaction between “component” and “hemifield” ( F (1,23) = 3.635; p = 0.069; μ 2 = 0.136).
There was also a strong trend that having a lower family income increased the likelihood of a child being at risk of delay ( p = 0.069).
56.9%, p = 0.022) (Figure 1a , S6a ) and a strong trend towards better RFS was also observed after evaluating maintenance therapy as a time‐dependent covariate (73.4% vs. 58.2%, p = 0.069) (Figure S6b ).