“a strong trend”

Analyzing total human SNCA amounts by ELISA, a significant reduction was observed following rHsCTSB treatment, while rHsCTSL showed a strong trend towards reduction ( p = 0.0569; Figure S5 G).

Although a significant increase in reward-seeking behaviors following sleep restriction was not observed, there was a strong trend ( p = .0569).

However, a strong trend towards an association between tumor cell expression of aromatase and ER was found, ( P = 0.057).

Although Dunn’s post hoc test did not show a statistically significant stress effect ( p = 0.535, stress-vehicle vs no stress-vehicle), SAFit2 showed a strong trend to reduce latency to drink ( p = 0.057 vs stress-vehicle) and fluoxetine ( p < 0.001 vs stress-vehicle) reduced the latency to drink in a bright novel environment suggesting effects on stressed-induced behavior.

Given we concomitantly observed a strong trend ( p = 0.057) for OXA-treated mice to interact with the food hopper, our data suggest that these mice might be waking more frequently to eat which is consistent with our nutrient deprivation hypothesis.

The mean score for “reading fine print” dropped to 3.82/5.00 and was significantly less than the +4.00/+4.00 cohort (p=0.02) and was almost significantly less than the +3.25/+3.25 cohort with a strong trend in that direction (p=0.057).

Since seven of our OS participants left our study before taking this (grapheme-personification) synaesthesia test, we repeated our analysis with the conservative assumption that all were non-synaesthetes and this still resulted in a strong trend for a higher prevalence of confirmed grapheme-personification synaesthesia for gender associations in the OS group compared to controls, χ 2 (1) = 3.618, p = 0.057, 95% CI [−0.004, 0.30].

In addition, there was also a strong trend ( p = 0.057) with Nx4 CEX rats spending 12.7 min more time in NREM sleep than Veh CEX.

However, there was a strong trend towards higher frequencies of CD4 cells ex vivo (p = 0.057; S4B Fig ) and Treg cells (p = 0.051; S5F Fig ) in parenchymal NCC compared to subarachnoid disease.

Although the ΔIOP following MAT did not reach a statistically significant difference compared to the other surgeries ( P > 0.05), a strong trend toward superior efficacy over trabectome was observed ( P = 0.057).

A strong trend towards a higher TLR rate was observed for the DIOR as compared to the IN.PACT Falcon (35 vs. 8 %, p = 0.057).

Although the Mann–Whitney U test indicated a strong trend towards significance ( p = 0.057), the difference did not reach the conventional threshold of statistical significance ( p < 0.05).

Guilt We found a strong trend to a statistically significant decrease in the weekly RSV for ‘mother guilt’ ( p = 0.057, − 61.80%*) in 2020 versus 2019.

Although there were no significant differences between the LSS group and the KOA group for any parameter, stride length variability demonstrated a strong trend toward a difference between the two disease groups (stride length CV; LSS 4.7 ± 0.8, KOA 4.0 ± 0.8, p = 0.057) with greater variability in the LSS group. 3.3.

Kaplan–Meier survival analysis revealed a strong trend for shorter median survival in cases with high CDK6 expression (Figure 5D : median survival 3.4 vs. 0.4 years; p = 0.057; log‐rank test).

Undetectable mannose binding lectin correlated with a strong trend toward poor survival in rheumatoid arthritis overall (P = 0.057).

However, a direct pre-post comparison using the Wilcoxon signed-rank test showed only a strong trend in the IE subgroup ( p = 0.057) and a non-significant change in the SE subgroup ( p = 0.174), suggesting that the Friedman test captured a substantial temporal effect driven by a sustained decrease. 3.3.

TBARS showed a strong trend to increase at 24 h following injury in WT mice, but this difference did not quite reach significance at the 95% confidence interval in this data set ( P = 0.057).

Consistent with our in vitro findings, in people with chronic hepatitis B there was significantly increased expression of PDK1, PDK2, and PDK3 compared to healthy liver ( Figure 7 A – C ), with a strong trend towards increased expression of LDHA ( P =0.057; Figure 7 D ).

However, in multivariable analysis, while there was a strong trend toward worse outcomes for patients with prior BCMA-DT exposure—particularly ORR ( p = 0.057 for ORR; p = 0.1 for PFS)—receipt of prior BCMA-DT was not independently associated with inferior ORR or PFS, as these differences did not reach statistical significance.

There were no other main or interaction effects [Contingency ( F 1,11 = 3.67, P = 0.082); Session × Contingency ( F 9,99 = 1.32, P = 0.24); Session × Group ( F < 1) although there was a strong trend toward a Session × Contingency × Group interaction (rmANOVA: F 18,99 = 1.67; P = 0.057)].

Following BIRT-377 treatment, a strong trend towards reduced levels of TNFα is observed in pain-reversed PAE rats (Fig. 8 b) ( p = 0.057).

When controlling for per cent solids, there remained a strong trend of greater Af growth in IL-1β-stimulated non-CF mucus compared with baseline (p=0.057).

psittaci CAL10 revealed low or background levels of sinC transcripts from 6 to 24 h postinfection (hpi), peaking at 30–42 hpi and decreasing sharply by 42 hpi, with a strong trend toward statistical significance ( H = 13.675, p = 0.057; Supplemental Figure S1B), similar to ct694 .

Sox2 high HPV-negative patients showed a strong trend towards enhanced DSS (p = 0.057) (Fig. 4c ).