Barely Significant
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“a strong trend”

5,726 sentences · 5,726 papers · 7,352 search hits before verification · confirmed specimen

Sighted at

p=0.077

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Nevertheless, prasugrel was previously noted to have a strong trend towards major bleeding including ICH in patients ≥75 years old and a related boxed warning was issued. 6 Since age is generally known as an important risk factor for ICH in patients on anti-platelet therapy, 38 future studies are needed to ensure the safety of intensification of antiplatelet therapy in elderly patients.
A recent retrospective cohort study of 5718 cardiac patients who received thoracic and/or head and neck RT showed a strong trend toward significant reduction in both cardiovascular and cerebrovascular events in patients on statin therapy. 1 Cardiac patients were defined as those who had a history of acute coronary syndrome or who had undergone any coronary revascularization procedure (percutaneous angioplasty or coronary artery bypass surgery).
In the study update in 2021, at a median follow-up of 35.5 months, Isa-Pd was found to significantly improve time-to-next treatment and PFS2 and there was a strong trend in OS benefit in the Isa-Pd arm (24.6 versus 17.7 months, HR = 0.76). 48 In 2020, the EMA and FDA approved the combination of isatuximab-Pd for MM patients who have received at least two previous treatments, including lenalidomide and a PI.