“a strong trend”

In men, a strong trend in the relationship between MTHFR SNPs and fertility has been demonstrated [ 7 ].

Previous studies on R6/1 animals failed to show any effect of the HD mutation on striatal DA tissue content [19] [20] , however these contradictory observations were more likely due to statistical limitations (they used n=3 animals per group only) since they nevertheless revealed a strong trend toward a reduced DA levels in HD mice.

Factors associated with HA in S3UR Compared with those without, patients who experienced HA in S3UR were more frequently on chronic hemodialysis, had lower rates of beta-blocker use, slightly lower hemoglobin at baseline, a higher degree of aortic valve calcification, and a strong trend toward more severe annular calcification ( Table 1 ).

Both clones initially grew faster, with one clone reaching statistical significance and the other one showing a strong trend (Fig. 4o ), but this growth advantage was lost as the tumors reached around 1.5 cm 3 in size.

11 The pre-specified subgroup analysis of the UNIRAD trial focused on the ET backbone as it appeared to be the only stratification factor with a strong trend towards an association with DFS, suggesting that patients treated with tamoxifen may derive a benefit from the addition of everolimus (hazard ratio 0.62, 95% CI 0.37-1.06, P = 0.044). 11 To further elucidate this intriguing finding, in this report we examine the interaction of ET and allocation to everolimus with age and menopausal status.

Overall there was a strong trend for sensory recovery in fasciocutaneous flaps over myocutaneous flaps (depressor anguli oris flap (Figures 5(a) , 5(b) , and 5(c) ), submental island flap, and pectoralis major myocutaneous flap) (p:0.09).

Greater endorsement of all hallucinatory IGC symptoms was associated with increased neighbourhood population density; this met conventional statistical significance on three of four items, with a strong trend in this direction for the fourth (non-specific visual hallucinations).

D-D demonstrated significant predictive value at 72 hours and showed a strong trend towards significance at 168 hours, but its accuracy is likely influenced by trauma-induced hyperfibrinolysis, which affects its specificity.

30.6 months), and there was a strong trend for additional benefit in patients harboring the 1p/19q co-deletion [ 4 ].

There was a strong trend towards both using samples for additional, unspecified research and sharing data with other investigators.

The hippocampus and caudate showed significant excess loss in the younger group ( p < 0.001) and a strong trend in the older-onset group.

As hypothesized, a strong trend could be observed during the first test, and shy children ( Mdn = 0.51, IQR = 0.36, range = 0–1.52) tended to be less successful in retrieving the taught words than their nonshy peers ( Mdn = 0.64, IQR = 0.27, range = 0–2.54), W = 122, p = 0.06, r = −0.35.

In 1975, Pickering 8 found a strong trend line between Math SAT scores and General Chemistry grades, and that a supplemental math/problem-solving course improved grades.

We failed to find a statistically significant difference, but there was a strong trend favoring plates with regard to reoperation rate.

In contrast, a plot having a relatively large distance between the position of the plot and the trendless line indicates a strong trend.

We admit that for the only characteristic with a strong trend, nestedness, we do not have any apparent explanation, especially because the trends strongly differed inter-seasonally.

We identified a strong trend toward CH-Tum being associated with the aggressive, mesenchymal GBM subtype (OR = 6.55 [0.70–61.1], logistic regression; Figure 4 B). 42 The mesenchymal GBM subtype is known to be particularly rich with immune infiltration compared to the other subtypes, which we observed in this cohort (mesenchymal vs. classical p adj = 1 × 10 −9 ; vs.

However, in the joint analysis we did not observe a strong trend between heritability and prediction accuracy (Table 1 ).

The authors did also suggest a strong trend for lower survivals in composite resin restorations, but, unlike the present study, did not find any statistical significance due to the very small numbers involved.

In a multivariate model assessing demographic and socioeconomic as predictors of ICT literacy, younger age (OR: 0.87; p = <0.0001) and higher education (OR: 1.18; p = <0.0001) were significant predictors of higher ICT literacy, while female sex (OR: 0.57; p = 0.051) showed a strong trend toward lower ICT literacy, and income and SES were not significant.

50 Pioglitazone showed a strong trend toward the primary outcome but did not achieve statistical significance over placebo.

However, prior to taking intelligence into account, there was a strong trend for older individuals to underproduce requested intervals and to have larger duration discrimination thresholds.

Conclusion Education preferences among emergency medicine providers vary with a strong trend toward online and on-demand content.

In addition, we observed a strong trend towards reduced Smad3 binding in the Dox washout experiments with SB that was present during Dox treatment only.

While we found that levels of inhibitory synaptic density in the thalamic VPM/VPL regions exhibited a strong trend towards a sex-dependent phenotype in both Grn +/+ and Grn R493X/R493X mice (Additional file 1 : Fig.