“a strong trend”

9 , 19 Although intestinal vaginoplasty may be performed in a minimally invasive fashion (ie, either robotic or laparoscopic harvest), there has been a strong trend away from the intestinal vaginoplasty as a primary procedure.

Lastly, grip strength correlated inversely with serum levels of IL-6, TNF-α, TGFB1 and MMP2, and showed a strong trend towards correlating with serum CTGF levels.

Similarly, HER2 analysis ( N = 506) from a study in Milan 79 demonstrated a strong trend toward survival benefit with anthracyclines only in those with HER2-overexpressing disease (OS CMF-A vs CMF HER2+: HR = 0.61, HER2− HR:1.26; p interaction = 0.052).

59.7%) showed a strong trend towards the failure of TVB but failed to reach statistical significance after using correction for multiple testing ( p = 0.06).

A strong trend emerged where patients with high KLF13 expression exhibited a substantially higher objective response rate (ORR) compared to those with low expression (40.0% vs. 6.7%; p = 0.0818, Fisher’s exact test; Figure 1 C, left panel).

Also, the meta-analysis revealed a strong trend in the proportion that deteriorated between placebo and IVIG-treated patients ( Table 4 ).

While there was a strong trend towards improved LOS with the use of OPEP compared to PEP, the study was underpowered to detect a statistically significant difference.

Notwithstanding, the qPCR analyses show that, in liver, expression of keys genes, such as DLK1 , LOXL4 , G0S2 , GSTA5 , HP , MT1A , IFI27 and SFRP1 was modulated at different extents (significant effects for five genes and a strong trend for three genes) by the vitamin treatments.

A key finding in our study has been a strong trend toward altered lipid metabolism between SD and WKY rats, which may, at least in part, explain differences in behaviour between the two rat strains.

There was a strong trend for a reduced prevalence of hypertension and dyslipidemia with increasing number of protective factors with those who scored four or more factors having approximately one-third and one-quarter the risk of hypertension and dyslipidemia respectively.

When evaluating the ACF and PACF of the series ( Figure 2 ), it is possible to verify a seasonal pattern in the lags of the ACFs/PACFs as well as an indication of a strong trend in the series, due to the slow decay found in the ACFs.

Limbs There is a strong trend to hind limb reduction when considering a single mesosaur taxon ( Fig. 5 ).

Interestingly, an increasing value of Delta CLIF-SOFA (p = 0.06; OR 0,5; 95%CI 0.2 - 1,0) presented a strong trend towards a significant association with increased mortality, as would be expected in patients with deteriorating clinical condition by day 3.

This study revealed higher expression of Ccr2 and Cxcr3 relative to naïve CD4 T cells, and there was a strong trend towards greater expression of Ccr4 in follicular T cells.

There is a strong trend towards clean label products and the use of the least possible amount of ingredients, and thus towards very limited use of food additives ( Asioli et al., 2017 ).

Cultures exhibited spontaneous spiking even at a very low density of 1,000 cells/cm 2 , with a strong trend toward greater total spike frequencies in co-culture conditions compared to control.

For the subchondral bone a strong trend for increased mRNA was found for CCL2 at day 14 which narrowly failed to reach statistical significance.

Randall and Downie have put forward three other common reasons for the popularity of measuring QoL: (1) It serves as a standardized quality mark for comparing different services and treatments; (2) It enables practitioners to provide better care for individual patients by learning about their ‘subjective symptoms’; and (3) At the time when these measures became more and more dispersed, there was a strong trend towards quantifying what is qualitative (Randall & Downie, 2006 ).

Accordingly, qPCR evaluation confirmed the up-regulation to be significant with stretch and a strong trend with tachycardia ( Figure 3 B). 2.3. miR-1183 as a Biomarker in Human Cardiac Tissue Considering the novelty of microarray findings, we further investigated whether miR-1183 is also regulated in chronic remodeling and might serve as a tissue biomarker.

Nonetheless, there was a strong trend towards increased grooming time in young rats injected with sera from autistic children compared to the sham group suggesting an increased tendency towards a spontaneous repetitive behavior ( Fig. 5A ; Bonferroni’s post hoc test, p >0.05; Student’s t-test, p = 0.014).

The IPTW-adjusted analysis confirms a strong trend favoring the CCRT+ICIs strategy at the group level.

The intervention did not reduce the primary outcomes, but a strong trend towards reduction was seen for the number of PIM DDD/res, which accounts for the doses used.

However, at least in Germany, there is a strong trend toward centralization for complex surgery of any kind.

show a strong trend toward lophodonty, however, the main cusp(id)s are not completely incorporated into the loph(id)s.

The second planned interim analysis, with a median follow-up of 6 years, indicates that although trastuzumab added sequentially to CT improves DFS, there is a strong trend towards a better outcome with concurrent trastuzumab relative to sequential administration [161] .