Whereas order parameters of individual resonances have the power of resolving detailed structural features of proteins (globular and ID alike), there is a strong trend in the IDP literature that uses global parameters of structure, disorder, and flexibility for approaching their function.
These studies, however, demonstrated a strong trend towards a higher risk of perforation with OA but were not powerful enough to show statistical significance with such a rare clinical event [ 17 ].
In fact, we found that success on the tasks (yes/no) was not repeatable, but we found a strong trend toward repeatable time to solve across tasks.
While not significant, statin use (p = 0.064), greater depressive symptoms (CESD score, p = 0.054), and lower sleep efficiency (p = 0.064) showed a strong trend with hs-CRP.
Remarkably, despite the relative small number of samples, we observed a strong trend towards a significant statistical difference in the RET immunostaining between samples carrying S836S/3’UTR ( GTCAC ) haplotype and those without these variants (392.7 (297–463) vs. 189.5 (152–324), P = 0.054; Fig 4B ).
The statistical analysis of the p53 immuno-positivity correlation showed a strong trend when associated with the presence of metastasis to the regional lymph nodes; however, without statistical significance, although p = 0.023; in these cases it was necessary to use the Fisher's exact, f = 0.056.
There was also a strong trend of more potent neutralization of the 16055Δ463 virus in this group after three immunizations, while the neutralization titer pattern for other single N-glycan-deleted viruses (16055Δ301 and 16055Δ360) was similar to the wt virus neutralization pattern at this time point.
Weekly food intake was significantly higher in MC4R -TB compared to WT littermates as expected, and although not statistically significant, there was a strong trend toward reduced food intake in MC4R -TB mice that received AAV-Cre-GFP injection into the vSUB ( Fig. 6E , F ).
There was also a strong trend in decreased lymphocyte counts in the tumor-bearing mice compared to the PBS-injected mice ( Figure 1 C).
A strong trend for reduced CD11B mRNA was also observed in the brains of urethane-treated rats [3.1 ± 0.5 ( n = 9 rats) for diazepam vs 1.6 ± 0.2 ( n = 13 rats) for urethane], although statistical significance was not attained ( p > 0.05, one-way ANOVA with post hoc Bonferroni r ; Fig. 7 C ).
The association between smoking more than 5 cigarettes daily during pregnancy and any Axis 1 disorder in the offspring became weaker (Ajd.OR 1.32, 95% CI 0.93–1.87); however, a strong trend still exists, suggesting that there are links between exposure to prenatal smoking and later psychiatric disorder in the offspring.
Christensen and colleagues [ 75 ] showed that increasing alcohol intake had a strong trend toward decreased DNA methylation.
While interaction testing did not reveal a significant interaction between obstructive lung disease and self-reported race/ethnicity, there was a strong trend towards significance.
levii antigens were greater ( p < 0.05) than background or no stimulation for all calf groups, including naïve, with a strong trend for similar results with the F. necrophorum antigen ( Figure 4A ).
To start to identify the role of estrogen in mitochondrial signaling, we analyzed the concentration of the estrogen receptor beta, which showed a strong trend for gender differences at four weeks of age.
This increased movement/exploration by APP/PS1 female mice and APP/PS1 mice fed a KD was also seen in the Y-maze test ( p < 0.01) with a strong trend for a sex × diet interaction (Supl.
A strong trend was revealed in the structure of screen time among Czech adolescents between 2002 and 2014 regardless of gender and type of day (weekdays versus weekend).
Across amphibians, we see a strong trend to shift reproduction from aquatic to terrestrial environments, which led to a rapid diversification of reproductive modes in early amphibians.
Previous research revealed that MPE impairs the cytotoxic effects of pemetrexed/cisplatin 19 , while our subgroup analyses showed a strong trend of negative correlation.
Furthermore, even though the cut-off values of CPI were not as similar as those seen in other pathological categories, they showed a strong trend towards prognosis, indicating the use of CPI as a cut-off to determine patients with high mortality, and showed a much stronger ability to rule out patients from having low prognostic status in cardiogenic shock. rather than in ruling them in.
No significant difference was observed in mRNA for M1 markers (despite a strong trend).
There is a strong trend toward the rational design of drug combinations using direct targeting of small molecules and finding new targets or new mechanisms of antimicrobial action [ 19 ].
In the past 50 years there has been a strong trend in philosophy to think that making moral responsibility judgements, such as blaming and praising, is an inherently social practice. 4 These judgements express reactions such as resentment or gratitude for how we have been treated by others and whether this treatment corresponds to our interpersonal
Consistent with this we found an increase in the phosphorylated Drp1 at Serine 616 ( Figures 4A – D ) and a strong trend to decreased MFN2 expression (Supplementary Figures S3 , S4 ) in RVfib in MCT-PAH, without significant changes in the other two fusion mediators (MFN1 and OPA1) (Supplementary Figure S3 ).
Signed-rank tests were used to determine statistical significance of biomarker changes, where P < 0.05 indicated significance; and 0.05 < P < 0.15 indicated a strong trend.