“a strong trend”

Therapeutic isotopes In addition to traditional imaging isotopes, there is a strong trend towards the production of therapeutic isotopes, as evident by the large number of sessions and individual talks.

As expected, the wound closure rate of diabetic rats was significantly delayed compared with non-diabetics; Gal-3 significantly promoted wound healing 3 days and 9 days after application, which was comparable to that of non-diabetic rats and Comfeel® dressing; VEGF showed a strong trend of accelerated skin wound healing, albeit without statistical significance (Supplementary Fig. 6F ).

Previous studies similarly either found negative correlations between the left hippocampal volume and negative symptoms in schizophrenics ( Rajarethinam et al., 2001 ), or at least a strong trend in this direction ( Brambilla et al., 2013 ).

Moreover, despite their lack of greater magnitude, the IFN-γ responses in DNA/Ad were statistically significantly associated with sterile protection (AMA1) or showed a strong trend (CSP).

25 The co-primary end points of this trial were radiographic progression-free survival (rPFS) and OS, which was met for rPFS, showing benefit in the abirater-one group (16.5 months versus 8.2 months, P <0.0001) but not for OS, though a strong trend toward improved survival was seen, but did not cross the O’Brien-Fleming efficacy boundary for statistical significance or the pre-specified statistical efficacy boundary (alpha-level: 0.0035). 26 Similar to the earlier study, unblinding was carried out after interim analysis and cross-over was allowed.

Notably, although not statistically significant, there was a strong trend for increased synaptic transmission within the Arc − population in mice receiving paired training, compared with the unpaired and naïve groups ( Figure 5b ).

Although the BA graphic shows a mean difference between the methods of only −0.31 units (95% CI: −1.10 at 0.48 ng/mL), it was observed a strong trend of IA to overestimate androstenedione values in comparison to LC-MS/MS when the mean of the two methods was increased, causing non-constant variation at all concentrations ( Fig. 4B ).

In pancreatic tissue, levels of the pro-inflammatory chemokine MCP-1 and cytokines IL-β were significantly reduced, as well as a strong trend for reduced TNF, and increased IL-10 (Additional file 1 : Fig.

Finally, among RA participants with anti–COL2A1‐885B (whose anticollagen multireactivity mirrored that of serum; Figure 3 ), those with multireactive sera had a strong trend of more frequently having DQA1*01:02 than those with limited reactivity sera.

5 , 11 Dowsett et al 31 identified a strong trend in the benefit from tamoxifen therapy for patients with ER-negative/PR-positive tumors.

A serious complication is renal cell cancer (RCC) that, in contrast to sporadic RCC, shows a strong trend towards multifocal and or bilateral manifestation.

9p deletions were linked to features of aggressive breast cancer such as high-grade and a strong trend towards reduced survival was found.

Principal component analysis of relative metabolite abundance per cell revealed a strong trend across the 54 cell lines (PC1, 58.9% explained variance, Supplementary Fig. 2 ), which strongly correlates with cell line volumes derived from cell diameters measured in ref. 66 as well as with the herein determined adherent cell size area (Supplementary Fig. 2 , see Supplementary Note).

Furthermore, there is a strong trend for light anesthesia to be a risk factor for a more intense (asystolia) reflex as compared with a regular depth of anesthesia underlying additionally the influence of light anesthesia to the autonomous nerve system.

The average number of co-authors per document was 3.83, highlighting a strong trend toward teamwork in pharmacological research.

IL-5 had a strong trend towards increasing; however without statistically significant difference (p=0.06).

Strikingly, in both control and Prrx1‐tBid dTG axolotls, the global pattern of CT cells exhibited a strong trend of progressive transition of the positional information (Figure 8A and Figure S13A,B , Supporting Information).

21 , 22 In our entire cohort, the MLAM‐IV resulted in a strong trend toward a longer duration of freedom from AF.

Here, we could corroborate the predictive value of Ang-2 and note a strong trend toward longer OAS in patients with high Ang-2 levels treated with bevacizumab.

Figure 7A shows that the knockdown of LmMet results in significantly decreased transcript levels of the chymotrypsin genes, LmChy1, LmChy2 (MWW; p < 0.01), while transcript levels of LmChy4 show a strong trend in the same direction.

Interestingly, we found a strong trend toward reduced expression of both PS1 ( supplemental Fig. 3, I and K ) and nicastrin ( supplemental Fig. 3, J and L ) in APP-hESC clones, although these differences failed to reach significance (ANOVA, p = 0.06, p = 0.12, respectively).

A strong trend toward specificity is reported in nearly all MH plants [ 1 , 6 ]: individuals are associated with a narrow fungal clade of fungus, and specificity results in local specialisation or even specialisation toward distinct genotypes within populations [ 7 , 63 ].

46 There were no differences between the two crime groups according to substance use history of youths and their families; however, family substance use history showed a strong trend toward more severe crimes.

hominis AIP-II-producing strain (AH4553) with MRSA resulted in a strong trend toward skin barrier protection as assessed by TEWL at 72 h postinfection ( Fig.

Consistent with our conclusion, there was a strong trend toward higher counts of peripheral basophils, tissue-infiltrating basophils, and tissue-infiltrating M2 macrophages in the non-responder group than in the responder group (p = 0.0333, p = 0.0007, and p = 0.0066, respectively) (Fig. 5 b).