Similarly, the instantaneous frequency of spontaneous synaptic currents was significantly higher in the Nulls, resulting in a strong trend towards a higher number of events within a 2-minute period as well (representative trace in Fig. 1B ; sPSC frequency: Wt, 17.4±1.3 Hz, n =51; Null, 21.8±1.5 Hz, n =53; P <0.05; number of events: Wt, 599.8±64.5; Null, 772.6±89.5, P =0.07), with no significant effect of genotype on sPSC amplitudes.
Although the findings of the present study showed a strong trend in this direction, data did not reach the level of statistical significance.
There is a strong trend of migration from rural areas to large cities, especially Ulaanbaatar.
The potential downsides include higher implant costs, the production of an injury to the articular cartilage, and the retention of metallic hardware. 13 There is a strong trend toward the use of headless cannulated screws in the treatment of boxer's fractures; although the results found were similar, new comparative studies are needed for electing the best method.
Therefore, micronized salt can be used to produce products with reduced salt contents, which is currently a strong trend.
Importantly, the Zn/O ratio exhibits a strong trend: increasing the temperature and duration of the water treatment causes the ratio to approach unity (1.0) ( Figure 5 a), indicating that the surface composition moves closer to stoichiometric ZnO (1:1 ratio).
TSPCs are a kind of mesenchymal stem cells derived from tendon tissue which have the potential of self-renewal and multi-directional differentiation [ 3 , 4 ], but because they come from tendon tissue, they express more markers related to tendon differentiation and have a strong trend of tendon differentiation [ 10 , 11 ].
The median BMIs for male patients who underwent ICU admission, intubation, paralysis, proning, and/or death were all higher than those who did not, either with statistical significance or a strong trend.
While there remained a strong trend towards fewer consultations among Spanish-speaking patients after adjusting for covariates, this difference was no longer significant (OR 0.53, 95% CI 0.23 to 1.18).
In terms of OS, based on the number of patients assessable, there is a strong trend for benefit in the recipients of Ara-C, but not for the recipients of MACE/MidAc.
In some breast cancer subtypes like PR+/ER+ breast cancer, positive SPAG5 expression presented a strong trend toward being associated with lower RFS (Additional file 3 : Table S5).
Analysis of the colon by region showed significantly less apoptosis occurred in the proximal colon compared with the distal or mid colon regions (p<0.001). There was also a strong trend (p-0.053) to indicate that the rate of apoptosis in the mid region was greater than in the distal region of the colon.
Additionally, we evaluated MASLD Activity Score (MAS), originally validated as a scoring system for human MASH 68 , 69 , and found a strong trend for less lobular inflammation and ballooning but similar steatosis in Lyz-IFNγR2 −/− mice compared to WT mice after the GAN diet, resulting in a modestly lower overall MAS in Lyz-IFNγR2 −/− mice (Fig. 5E ).
There was a strong trend in the number, but not proportion, of IFN- γ + CD8+ T cells in the tumor after the combination treatment ( Fig. 5(i) , (k) ), indicating that the alteration in CD8+/Treg ratio correlates with an increase in IFN- γ production.
For most practical purposes, there does not appear to be a strong trend between recovery efficiency and the inoculation level, although there appears to be an ∼2× increase in recovery efficiency of the TX3211 wipe once exceeding a certain target inoculation level between 160 and 400 CFU.
A strong trend toward an age-related deficit on reversal learning problems was also described in this same cohort of aged rats, and reversal and EDS performance were strongly related.
Older age had a strong trend for more cough frequency during treatment in our models ( Table 2 , Table 3 , Table 4 ).
Intriguingly though, a second HFD challenge in adulthood resulted in substantially increased insulin levels and the HOMA-IR indicator of insulin resistance in early-HFD mice and a strong trend of higher levels in early-R-HFD compared to early-CD mice ( Figure 4 G,H).
Risk of total mortality significantly increased with decreasing number of health behaviours, with a strong trend observed.
Despite these limitations, ITEM is conceptually sound and technically feasible: on exposure to a standardized force of impact-induced sheer, clots of coagulopathic blood fail to stay intact; there is a strong trend toward failure of clots under ITEM with higher dilutions.
Despite not reaching statistical significance ( p = 0.078), SsM18 supplementation showed a strong trend toward reducing the risk of belonging to the ‘Rapid-Onset, Severe’ trajectory (odds ratio [OR] = 0.34, 95% CI: 0.10–1.10).
There is a strong trend towards inferior OS in MC078E cohort that might not have reached statistical significance due to small sample size (specifically, the small number of deaths).
Previous research on NMIBC has revealed a strong trend to focus only on predicting grading, staging, or the degree of muscle layer invasion. 32 , 33 , 34 Conversely, few studies have examined the comprehensive diagnosis of NMIBC, particularly the critical differentiation between non-malignant disease and malignant carcinoma.
Mice treated with miR-155 inhibitor had a strong trend toward decreased miR-155 expression by 3d p.i. compared to LNA scramble-treated mice.
Interestingly, a strong trend of protein depletion was observed, with no proteins enriched in saliva from iSGs.