Compared to other animal groups, there was a strong trend for SHRs consuming the milk fermented with Lb. bulgaricus Lb100 to have increased level of TEAC and decreased level of TBARS in the blood, which suggests their better oxidant/antioxidant status.
However, while metoprolol had no effect on basal or maximal OCR, verapamil showed a strong trend in that direction (Fig. 8e ).
Sub-optimal supply of nitrogen caused a strong trend for the domesticated lettuce phenotype to converge with that of the wild type, resulting in a narrower range of concentrations for each metabolite studied.
There was a significant effect of family background on the gene expression of sterol regulatory element binding transcription factor 1 ( srebp1 ) with a relative increase in HIGH compared to LOW and a strong trend towards a dietary effect.
3 ), did not show a strong trend, with seemingly random peaks and troughs throughout the time period plotted.
Similarly, in the French data, a strong trend was observed for the cardiovascular events to occur less frequently in the LT group than in the HT group, although the difference was not statistically significant (0.66 [0.37–1.20], P =0.180).
Qualitative analysis found a strong trend showing a reduction of sadness, and feeling of increasing empowerment.
We also performed supervised recurrence risk prediction analysis and identified a profile consisting of a subset of mRNAs (miRNA gene targets) that showed a strong trend in distinguishing good and poor prognosis tumors, although not as strongly as the miRNA levels themselves - probably as a result of a smaller sample size in this analysis ( n = 37, median RFS 28 months versus not-yet-reached, log rank P = 0.260; Figure 4C ).
Researchers found that there has been a strong trend toward the development of core capabilities through knowledge exchange, investments in relation-specific assets, and complementary capabilities [ 18 ].
Yet, this latter trial showed a strong trend but failed to show a statistically significant reduction in bleeding events in the dual therapy arm compared to TAT. 3.5 Rationale for choice of antithrombotic treatment The PIONEER-AF-PCI [15] trial used a modified dosage of rivaroxaban [31] .
A relevant fact is that there is nowadays a strong trend between fashion and art consumers to shift preferences toward more sustainable wearable goods, even in exchange for relatively higher prices (Gorman 2020 ).
However, there was a strong trend for decreased alveolar bud diameter in Akt1 −/− mammary glands, concomitant with increased epithelial cell apoptosis ( Fig. 5 B, D–F ).
Universal Kriging is used to estimate spatial means when the data have a strong trend.
In this subset of patients, we did not observe a strong trend regarding disease activity across the observed time frame of inclusion ( Fig. 1 ).
However, our cohort maintained stable body weight, increased their energy intake, obtained a larger than expected increase in hbmass (Koivisto et al., 2018 ) and demonstrated a strong trend for increase in s-testosterone [a biomarker for energy availability among male athletes (Mountjoy et al., 2018 )].
Among tumor stem cell regulatory agents, tarextumab initially showed encouraging results in a Phase I study; however, an interim analysis of a Phase II study showed a strong trend to a lack of benefit, and the trial was discontinued due to futility (ClinicalTrials.gov Identifier: NCT01647828 ;[ 15 ]).
Comparison based on ordinal BEC- F ENO three-group categories of T2 inflammatory burden showed significantly greater lung function improvements and a strong trend towards better symptom control in T2-High attacks.
During the Prevail Phase 2 trial for ZMapp, clinical promise was observed with a strong trend toward improved survival, although efficacy metrics were not reached due to patient access as the Ebola outbreak dissipated.
Many of these differentially expressed genes were also differentially expressed between mdx and e23AON-treated myofiber nuclei (68% in type IIx, 41% in type IIa, 78% in type IIb), with a strong trend toward e23AON-treated nuclei recovering a more WT gene expression (Fig. 3c ).
Recent randomized trials have confirmed that ablation is overwhelmingly more effective than traditional pharmacological therapies for AF, with a strong trend to superior safety.
There was also a strong trend for the quality of pLDDT estimates to correlate with the fraction of models that contained individual pLDDT estimates (and therefore would have been derived from AlphaFold3 models).
However, eyes that received MP laser showed a strong trend towards greater BCVA improvement.
Cells devoid of LRRK2 or expressing LRRK2 DM displayed a strong trend of lower NF-κB activation relative to LRRK2 WT cells for both wild-type and mutant NOD2 ( Fig 4F ).
We also observed a strong trend that low ATM group (tATM, nATM and csATM) had worse DFS than high ATM (tATM, nATM and csATM) group with a P value of 0.05 to 0.09 based on log-rank tests of KM analysis (data not shown).
(2016) also found a similar increase in SPN event frequency in slices from similar GKI mice (aged < 1 month) ( Matikainen-Ankney et al., 2016 ), which was concluded to be predominantly due to action potential-mediated transmission (only a strong trend toward increased frequency was observed in the presence TTX).