“a strong trend”

There was also a strong trend of decrease in blood vessel surface area following ETC-159 treatment ( Figure 3 h), almost reaching statistical significance.

Successful early recanalization had a robust association with excellent outcome (aOR, 2.29 [95% CI, 1.23–4.28]) and ordinal mRS (adjusted cOR, 0.57 [95% CI, 0.34–0.96]) as well a strong trend towards an association with good outcome (aOR, 2.10 [95% CI, 0.998–4.43]).

A strong trend for a reduction in dendritic spine density was also reported by Selemon et al.

In addition, we also noted a large intertumoral heterogeneity in tumor volumes, this may have impacted the lack of statistical significance in our H460 model, even though we noted a strong trend toward decreased MGMT and increased CRT efficacy by AMONs.

This is indeed a strong trend, with 118 out of 127 drugs having a higher proportion of correctly predicted sensitive cell lines using the multi-gene markers.

There was a strong trend toward increasing airway wall thickness, more airway narrowing, and reduced airway branch count in patients with different stages of lung impairment.

A strong trend for higher levels of inflammatory cytokines was observed after SmyleDCpp65 administration (IL-4, IL-10, IL-5, IL-6, IL-8, and in particular high levels IFN-γ, GM-CSF, TNF-α, and MCP-1) ( Figure 4b ) ( Supplementary Information, Table S2a ).

For example, there is a strong trend in epidemiologic studies suggesting an association of ASDs with exposure to atmospheric mercury and cadmium.

SOL nEMG increased immediately after fatigue in both sexes, reaching statistical significance in males (119.3% ± 34.9%; p = 0.048, d = 0.55) and showing a strong trend in females (116.8% ± 27.1%).

On average, however, there does not appear to be a strong trend in decreasing genetic diversity towards the edges of the species range for most species.

However, when the two groups were compared regarding baseline to endpoint A1C, there was no statistically significant difference (p = 0.051), although this borderline p value could indicate a strong trend in favor of self-adjustment and a result of clinical significance.

Aiming at reaffirming our findings, we evaluated its clinical significance in the institutionally-independent OVCAD multicenter validation cohort, which highlighted a strong trend between i-tRF-GlyGCC increased levels and the poor survival expectancy of the patients.

There was a strong trend for a significant time course effect for HADS.

Additionally, patients were stratified based on MGMT promoter methylation and a 9-gene signature; however, they did not identify a group of patients who demonstrated benefit from first-line use of bevacizumab, but patients with MGMT promoter methylation and a favorable 9-gene signature showed a strong trend towards a worse outcome.

A strong trend towards a significant treatment effect on plasma NfL concentrations was observed over the 6-month interval in response to 50 μg HTT ASO treatment initiated at 8 months of age (Fig.

A strong trend has been reported for reduced glutamate in white matter after 8 weeks of GAA supplementation (decrease of ∼4.5% from baseline levels) in healthy men ( Ostojic and Ostojic, 2018 ).

AU6 and AU12, respectively), and the Corrugator showed a strong trend for the same type of response specificity, with greater frowning in response to stimuli containing frowning.

Although there is a strong trend to use PROMs for benchmarking purposes [ 12 ], there still remains a lack of case-mix models to predict patient-reported outcomes as compared to clinical outcomes [ 11 ].

9 The PROTECT II (A Prospective, Multi-Center, Randomized Controlled Trial of the IMPELLA RECOVER LP 2.5 System Versus Intra Aortic Balloon Pump [IABP] in Patients Undergoing Non Emergent High Risk PCI) randomized control study demonstrated that among 443 symptomatic patients with complex CAD and severely reduced left ventricular ejection fraction, patients supported with Impella 2.5 had a strong trend towards reduced major adverse events at 90 days compared with those who were supported with an intra-aortic balloon pump. 10 Subsequently, patients from the more contemporary, prospective, multicenter PROTECT III study were compared with similar patients from the PROTECT II study, which demonstrate

This study presents a strong trend towards the presence of poor sleep in both males and females, elite and sub-elite GAA athletes.

However, even in the fully-adjusted model (model 4) a strong trend persisted (p-trend <0.0001).

When considered separately, the cohorts with known CHD and those without demonstrated a strong trend to lower event rates with lower group mean LDL-C during treatment with either drug (simvastatin) or placebo.

This distribution again indicates that Dim1 is more strongly linked with antioxidative enzymes, while Dim2 does not exhibit a strong trend either way.

But there was a strong trend for a negative correlation in the PD group without a negative correlation with disease duration.

Prior vaginal delivery and uterine rupture All studies found a lower risk of uterine rupture for women with a previous PVD, three studies showing a significant risk reduction and two studies showing a strong trend.