Biological Pathway Insights Two pathways were notably altered: alanine, aspartate and glutamate metabolism was the most significantly disturbed pathway in both enrichment and topology analyses ( p < 0.05 for both), and tryptophan metabolism was significantly altered in the enrichment analysis while showing a strong trend toward significance ( p = 0.058) in the topology analysis.
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A strong trend toward significance time-of-the day x substance interaction was observed in Fat max ( P = 0.058; Fig. 3 ).
The mean CLH2 expression differed significantly, and 45M1 had a strong trend toward significance ( p = 0.06) among the three groups ( Figure 1 B).
Furthermore, there was no interaction effect for this measure, however there was a strong trend toward significance ( F (4,52) = 2.42, p = 0.06).
There was a significant effect of prior cocaine exposure on cocaine-induced ambulatory activity in adult controls ( p < 0.001), and a strong trend toward significance in nicotine-pretreated adults ( p = 0.06).
In a retrospective cohort comparing MA and RIC regimens in 51 patients with MF observed no significant differences in 3-year OS or PFS (OS 44% vs 31%, PFS 44% vs 24%, respectively) however the relapse rate was lower 12% vs 46% in RIC with a strong trend toward significance (p=0.06) ( 62 ).
A one way ANOVA comparing group performance in the acoustic condition of the rhythmic synchronization task after 1 year of training showed a strong trend toward significance F (1,30) = 3.54, p = 0.06 with the music group outperforming the control group.
Lower NIHSS scores at admission showed a strong trend toward significance (OR: 0.716, 95% CI: 0.505–1.015, P=0.061).
Although gap distance remained independently associated with stricture formation in multivariable analysis, anastomotic leakage showed a strong trend toward significance (adjusted OR 2.43, 95% CI 0.99–6.48, p = 0.061).
INTEM A5 showed a strong trend toward significance (+ 5.14 mm, p = 0.062).
Post-hoc t -tests showed that omissions occurred more frequently than substitutions and confusions [ t (1, 111) = 18.61, p < 0.001, t (1, 111) = 15.7 p < 0.001], and that the listener two groups showed a significant difference for substitutions [ t (1, 111) = 3,05, p = 0.03], a strong trend toward significance for omissions [ t (1, 111) = 1,86, p = 0.065] but no significant differences in confusions ( p < 0.05).
The Charleson Comorbidity Index (CCI) showed a strong trend toward significance ( p = 0.065), while age lost statistical significance after adjusting for comorbidities.
Classification skills showed a strong trend toward significance ( p = 0.065), suggesting a potential moderating role of attitude that warrants further investigation.
Similary, a strong trend toward significance was observerd for OS (18.04 vs 12.09 mo; HR: 0.53 [0.25–1.29] p = 0.07) (Fig. 4 ).
The use of two or more permanent clips was more frequent in large aneurysms (n = 10/11; 91.0%) compared with standard aneurysms (n = 21/36; 58.3%), with a strong trend toward significance ( p = 0.07).
13.4%; p = 0.004), with a strong trend toward significance in the PSM cohort (33.9% vs. 13.7%; p = 0.07).
Key Drivers and Borderline Moderators Although no single variable reached the traditional threshold for subgroup differences, Intervention Duration emerged as a key moderator with a strong trend toward significance ( P =.07).
History of periodontitis also demonstrated a strong trend toward significance ( p = 0.07).
It was also shown that P50 amplitude was significantly greater in the VTd versus the TVd condition at electrode P4 ( F 1,14 = 4.87, P = 0.033) with a strong trend toward significance for the same effect at CP4 ( F 1,14 = 3.37, P = 0.07) (refer to Fig. 5 A).
Analysis of microbiome variation in relation to spatial distance between sampled tissues revealed a strong trend toward significance ( p = 0.07) with a substantial effect size (R 2 = 0.207).
7.3 [SD 10.7], P = 0.03) compared to those of the other two classes, and BPI Pain severity at 6 months showed a strong trend toward significance (0.3 [SD 0.7] vs. 1.4 [SD 1.8], P = 0.07).
Consistent with these findings, biochemical assessment of complex-V (ATP synthase) activity revealed that LPS exposure reduced enzymatic activity relative to sham controls, with a strong trend toward significance ( p = 0.08; Fig.
For the early cluster, post-hoc t -tests revealed a strong trend toward significance ( p = 0.08) for the comparison in the left hemisphere and a significant difference for the comparison in right sensors ( p = 0.03).
The improvement over the 3DT1W MRI model showed a strong trend toward significance ( z = −1.735, p = 0.083).
This effect was enhanced in the combined therapy, however, remained only as a strong trend toward significance ( Figure 2E ) (one-way ANOVA: F = 2.723, P = 0.087; SNK test: q = 3.978, P = 0.057).