Here, a slight trend for hemolytic anemia in T2D patients was too mild to emerge from routine hospital analyses based on indirect biomarkers of hemolysis (AST, iron, bilirubin and LDH), known to be impacted by the many metabolic modifications that prevail in T2D.
Even if a slight trend towards more regular use in patients instructed to use the NNS hourly was observed, the minimal inferred average intake for the control group is clinically sufficient to justify the actual recommendation to use the substitute when craving appears.
A slight trend for fewer cone bipolar cells was observed in cKO/DM and cKO/NDM mice compared to WT/DM and WT/NDM mice, although it did not approach significance ( Fig. 3 ).
The results on pore volume, determined by thermoporometry, were not significant, but there was a slight trend towards larger pore volume with FC, which is supported by the findings on bead density.
While gender was not a statistically significant predictor in our study, we observed a slight trend towards higher odds of microvascular complications in males, suggesting the need for further investigation into potential gender-specific risk factors [ 30 ].
A meta-analysis of cognitive behavioral interventions among patients with breast cancer undergoing active treatment reported that these techniques had a significant effect in reducing anxiety and depression, and reported that while therapy length or delivery did not significantly moderate the effect, individual therapy showed a slight trend toward eliciting better results on distress outcomes [ 13 ].
TNF- α is strongly expressed in animals treated with MCD compared to HFD feeding where it shows only a slight trend to be upregulated.
The difference in knowledge scores between males and females approached statistical significance ( p = 0.056), suggesting a slight trend towards higher scores among females.
[ 21 ] show a slight trend favoring arthroscopic surgery with an SMD of 0.31, but the CI crosses zero, indicating that this difference is not statistically significant.
The θ d5 values are similar and independent of the polymer composition, with a slight trend of decreasing θ d5 with higher PI x content and range from 322 to 334 °C.
Our data showed no statistical differences among assessed groups in terms of velocity, even if a slight trend of speed increase was found in OW participants respect to the others participants.
Background 'y-radiation also showed a slight trend in risk for lung cancer, with an odds ratio of 1.1 (CI, 0.9-1.4) (11).
Although the proportion of ACB susceptible to meropenem showed a slight trend toward increasing over time, the overall resistance rate was high at 36.5%, posing a problem for the empirical use of this agent ( Table 1 ).
Inequality in mortality was relatively stable but still showed a slight trend towards increasing.
Regarding Mean HR, Min HR, and Max HR, no statistically significant differences were found, except for a slight trend toward lower variability amplitude in the CLBP group.
This observation is supported by a P value of 0.06 (Figs 2 ; S2 ), suggesting a slight trend of increase towards benign lesions and healthy conditions.
In contrast, COL1A1 expression was not significantly affected by meso-scale structural modification at any time point, although a slight trend toward increased expression was evident at day 7 for all modified surfaces compared with unmodified zirconia.
There was even a slight trend that diploid fish got infected earlier.
Self-reported health was generally rated as poor or fair across groups, with a slight trend towards better ratings among rural participants.
When the analysis was performed separately in the two periods of time (2005–2014 and 2015–2023), early mortality showed a slight trend to decrease over time in both cohorts, without statistical significance.
We also tested for a correlative relationship between abundance of Δ9-THC in leaves and flowers and detected a slight trend between Δ9-THC content in leaf and only the flowers from the upper portions of the plant however there was insufficient statistical support for this relationship ( S1 Fig ).
Yet, long-term survival rates are comparable to open surgery, with a slight trend towards higher perioperative mortality in open surgery.
For PACE-B early toxicity results are available, showing no significant difference between the treatment arms with a slight trend in favor of the SBRT regime (23% vs. 27%) [ 38 ].
In addition, 10 of 14 nuclear markers in domestic pigs were detected to have a higher proportion of pairs with significant LD than in wild boars ( Table 4 ), suggesting a slight trend toward increasing LD in nuclear DNA during domestication or breeding, which is consistent with founder effects.
We also noted a slight trend for higher cfDNA concentrations in patients with CNS lesions, which may be a further indicator of higher overall tumor burden.