A slight trend of lower molecular weight and number of heavy atoms is also present with the top 10 scorers pointing to lower molecular weights and a larger number of hydrogen atoms relative to heavy atoms present for these ligands.
In contrast, Shot‐PC::GFP (another natural isoform which lacks CH1; Figure 1a,c ) failed to induce either of these phenotypes; instead it showed a slight trend to suppress spool numbers below control levels (Figure 1c,l ), as observed in previous studies (Sánchez‐Soriano et al., 2010 ).
P/A ratio was similar in different age groups, while ΔK showed a slight trend of decrease with the increase of age.
In vitro investigation of the rutin compound showed a slight trend towards inhibition of CRC cells such as HT-29 and CaCo-2 13 .
There was a slight trend for CD34 + and CD133 + cells to be decreased during different time points after day 7, although this was not significant.
In our study, we observed a slight trend toward better outcomes among individuals with higher educational levels.
Although there was a slight trend toward a reduction in NAD+ levels in ATM-KO cells, no significant reduction in NAD+ levels was detected in either ATM-KO or WT cells after PARGi treatment (Supplementary Fig. 2 D).
The calculations started from the quantum-refined structures where w x = 0 and 100 give the most and least negative energies, respectively, and the variation is rather random but with a slight trend that the strain energy increases with w x .
23 - 35 While average participation is 41% (range 35%–47%), there is a slight trend towards improvement over time.
Additional analyses were also performed on the predicted CRISPRa activity with different factors, such as gRNA length, with a slight trend showing increased activity, with longer gRNAs going up to 23 bp [ 39 ].
A slight trend was observed, indicating that larger intended positional offsets tended to result in greater deviations.
We observed a slight trend of relatively shorter than expected (given polygenic height score) adult statures among individuals with one or more childhood stress markers present ( SI Appendix , Fig.
A slight trend towards lower NAbs induction in the MVA-CoV2-B2AT group compared to the MVA-CoV2-BMEP group was observed.
For some other pests evaluated, plots with mass releases of earwigs had a slight trend in overall lower pest density when compared with control plots.
There was a slight trend towards decrease in the phosphorylation levels of AMPK (Thr172) in KKay mice with PM 2.5 exposure at 5 and 8-weeks compared with FA controls (Figure 8 C).
Complement component C3 also showed a slight trend towards down-regulation ( Fig 2C “stress”).
Regarding advanced SPs and AN, there seems to be a slight trend to decrease with time, but no statistical significance was reached in either case.
Despite a slight trend towards decreased motor performance, nes-CrT –/y mutant mice did not differ from CrT +/y and nes-CrT +/y mice in the rotarod task, with a similar fall latency at all ages tested (Fig.
Thus, there is a slight trend for a common variant located within an EBNA2 ChIP-seq peak to influence gene expression in EBV-infected B cell lines.
A slight trend toward better therapeutic effect was observed with systemic administration, although the differences remained small compared to local application.
In addition, a slight trend towards lower production of TNFα, a cytokine positively correlated with IFNα in SLE patients was also observed.
Most of the decrease in competing mortality was attributable to lower non-cancer mortality, but we also found a slight trend for lower second cancer mortality (Supplementary Table 3).
At time of challenge, the opsonizing activity of milk, as assessed by the survival of bacteria incubated with blood neutrophils and 20% milk, did not vary significantly (p = 0.23) between groups despite a slight trend in favor of the immunized cows (Fig. 11b ).
There appeared to be a slight trend toward lower acceptability of the telehealth clinician modality compared to the in-person clinician modality in our small trial.
[ 16 ], including seven articles, found a slight trend favouring arthroscopic washout over open treatment, although this was unlikely to be clinically relevant in most cases.