Consistent with the pharmacokinetic experiment, we observed an association between plasma dexamethasone concentration and asparaginase activity (P = 0.005; S1 Fig ) at the end of 6 weeks in the osteonecrosis experiment, In the 27 mice that received both dexamethasone and asparaginase, there was a significant trend towards higher dexamethasone levels (P = 0.027; Fig 4A ) and higher asparaginase activity (P = 0.036; Fig 4B ) in osteonecrosis-positive cases.
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“a significant trend”
Sighted at
p=0.09
In the literature
Specifically, a significant trend was observed during the pre‐1997 period ( τ = 0.1149, p = 0.0271), whereas the post‐1997 period showed no statistically significant trend ( τ = 0.0605, p = 0.1432), indicating relative stabilization of water quality conditions after the late 1990s.
Subgroup analysis based on ER status showed CA125 response rates of 0% (immunoscore of 150-199), 12% (immunoscore of 200-249), and 33% (immunoscore of 250-300), with a significant trend observed (P = 0.028, χ2 for trend).
A significant trend towards increasing prevalence across the different tertiles of MSG intake was observed for the prevalence of insulin resistance (P = 0.028), overweight (P = 0.021), and metabolic syndrome (P = 0.014).
When stratified based on HDI or income levels, there was no significant difference in MIRs; however, a significant trend of increasing MIR with decreasing HDI ( p = 0.028) and income levels ( p = 0.016) was observed.
A significant trend of UA in the three capillaroscopic patterns was shown (3.90 ± 1.52 vs. 4.15 ± 0.98 vs. 5.38 ± 2.26; for early, active, and late patterns respectively, p = 0.028).
Results The expression of VEGF and HIF2α showed a significant trend with tumor differentiation (p = .028 and p = .006, respectively).
We also observed a significant trend toward greater BuChE inhibition by number of Q alleles ( p = 0.028).
Among centers with available volume data, there is a significant trend of decreasing mortality with increasing volume (HR 0.579, p = 0.028).
We found a significant trend towards higher levels of Lp-PLA2 activity in VAD compared with the other groups (ANOVA, p = 0.028).
There was a significant trend towards less use of cannabis (Fig. 3c , P = 0.028 and P = 0.456 for time components) and benzodiazepines (Fig. 3g , P < 0.001).
Interestingly, there was a significant trend showing that abdominal injury severity increased as the L4 subQ fat ratio decreased (β = −0.008, p = 0.028). 4.
There was a significant trend toward an increase in the incidence of severe DKA over time [Odds ratio (OR) = 1.03, 95% CI: 1.003–1.05, p = 0.028], with an average increase of about 3% per year during the study period.
Furthermore, a significant trend (P-value = 0.0283) for fat intake was observed (Table 3 ).
There was a significant trend over time in the rate at which women seroconverted (p-value = 0.0283), and this is graphically illustrated in Figure 3 .
Relationship between VDG and Diagnostic Accuracy The diagnostic accuracy of MMG was 81.4% (359/441) among all patients (84.2% [48/57], 84.2% [148/173], and 77.3% [163/211] for patients in VDG: a + b, c, and d, respectively), highlighting a significant trend in which the diagnostic accuracy decreased with increasing VDG ( p = 0.0284).
There was a significant trend to achieve pT0 status, i.e. with complete tumor regression and a TRG score of 0 in the primary tumor site in the NACRT group ( P =0.0284).
In addition, there was a significant trend toward lower BMI among the younger parents ( p = 0.0286).
3b , there was a significant trend towards increased dynamic MAE through the pre-test day to the 3 rd training day ( t (14) = 2.43, p = 0.029, linear trend analysis), hinting that attention might be a not-to-be-ignored factor contributing the changes in perceptual aftereffects in repeated adaptation.
There was a significant trend toward lower BMD ranging from healthy to poor sleep pattern ( p = 0.029).
Also, the change in slope was increasing despite being insignificant which resulted in a significant trend of 0.335 cases/month during the COVID-19 period (p-value = 0.029) (Fig. 2 G).
Results (Table 1 , Figure 1 ) Medical respiratory ICU (MRICU) We found a significant level increase ( = 0.136, P = 0.036) after nurse leader escalation and education/executive leadership SBAR followed by a significant trend decrease ( = –0.063, P = 0.029) in test normalized CAUTI rate.
There was a significant trend of upgrading by increasing age (p = 0.029), other age comparisons were not statistically significant.
A significant trend in breast cancer screenings across calendar months was only present in 2019 ( p = 0.029).
In particular, patients with active glomerular lesions, but without chronicity, showed the greatest improvement in eGFR slope; a significant trend was observed ( p = 0.029) ( Figure 5B ).