“a significant trend”

There was also a significant trend towards lower harm categories for incidents over the duration of the project (Chi Square test for linear trend, r= -0.21, p<0.01).

If a significant trend was detected at p ≤ 0.01, Williams’ test was used [ 21 ]; if the trend was not significant Dunnett’s test was used [ 22 ].

A significant trend of FT3, FT4, TSH and TPOAb was presented among the control group, EU group, SHO group and HO groups (all P < 0.01; Table 1 ).

Conversely, in the population of patients with sperm abnormality, we found a significant trend increase from day 1 to day 7 of TSC (16.38 vs. 56.0; p<0.01), sperm concentration (million/ml) (8.0 vs. 18.0; p<0.01) and morphology (3.0 vs. 5.0; p<0.01).

The current study results consistently demonstrated a significant trend ( P < 0.01).

The fully adjusted model demonstrated a significant trend correlating increased TTHC (P<0.01 for trend), SR (P<0.001 for trend), and Ki-67 expression (P=0.004 for trend) with ALNM.

Compared with the latter, our cohort presented increased mutation frequency of DUSP2 , BTG2 , IRF4 , MEF2B , MYC , CD79B , BCL7A , NFKBIE , FAS , and CIITA ( p < 0.05), with a significant trend toward changes in TP53 , CCND3 , CD58 , and CXCR4 ( p < 0.01).

7 a), while protein breakdown demonstrated a significant trend (p = 0.01, Fig. 7 b).

In the >4 weeks treatment duration subgroup, meta-analysis indicated a nonsignificant trend for reduction in SBP between experimental and control groups [WMD = 0.55, 95% CI (−2.63, 3.72), P = 0.735]; however, in the subgroup with treatment duration ≤ 4 weeks, there was a significant trend for reduction between the two groups [WMD = −4.42, 95% CI (−6.29, −2.20) P < 0.01] ( Figure 7 , Supplementary Figure 10 ) .

However, this better prognosis was time dependent with a significant trend toward late recurrence with ILC compared to IDC ( P < 0.01). 3 Rakha et al 4 showed that ILC has an indolent but progressive clinical course with nearly linear survival curves which cross those of IDC after approximately 10 years of follow up, thus eventually exhibiting a worse long-term outcome.

Despite the variance, however, there was a significant trend for enhancers to have higher H3K27me3 levels in the uninduced versus active state ( P < 10 −2 , Wilcoxon rank-sum test) ( Fig. 3 B), consistent with previous findings ( Bonn et al. 2012 ).

Patients with grade 2/3 neutropenia were significantly younger (mean age 48 years) than those with grade 4 neutropenia (mean age 52 years, P <0.002), and overall there was a significant trend for higher grades of neutropenia in older patients ( χ 2 for trend=6.87, P <0.01).

Although the 7 items out of 26 in the impacts domain also showed a significant trend with both lung functions (both P < 0.01; Table 4 ), these items are more diversified, not easily remembered, and thus less feasible in clinical application.

There was a significant trend in decreasing agreement across increasing Ct groups (p < 0.01).

There is a significant trend towards longer-duration warm events (slope = 7 d decade −1 , r 2 = 0.3, p = 0.01), with the mean duration increasing from 8 d during the 1980s to 26 d during the 2010s, but there is no significant change in the duration of cool events (mean value = 12 d, p = 0.18).

A significant trend was noted in these patients as they exhibited increased intratumoral PMN infiltration post-RT treatment compared to their baseline pre-RT ( p < 0.01) (Fig. 6c ).

There was a significant trend in the survivor functions (i.e., probability of remaining free from diabetes) across the quartiles of greenspace ( p = 0.010) (Fig. 1b ); the probability of remaining free from diabetes amongst those in the greenest areas was 2.4% higher than those in the least green at age 80.

The average changes in ln(UACR) for participants in the 2nd, 3rd, and 4th quartiles relative to the reference quartile were respectively − 0.06, 0.08, and 0.22, presenting a significant trend ( P < 0.01).

Gestational week at examination, LDL-C, HDL-C, and GWG showed a significant trend of first increasing and then decreasing with the TyG index ( P < 0.01).

Furthermore, there was a significant trend comparing livestock farm living, village and city living ( p < 0.01).

Only topics with a significant trend in both frequency and rank (ie regression coefficient P -value <.01 in both the frequency and rank regression models) were retained for further analysis.

With respect to transcendent orientation, the mean score was higher in women ( P = 0.03) and in those working < 30 h/week ( P = 0.03); a significant trend also emerged in the mean COPE-NIV-25 score, which increased with age ( P = 0.01) and length of employment ( P = 0.01).

Linear regression analysis of the time-to-knockdown and mean cuticle thickness ( Fig 4 ) revealed a significant trend (p < 0.01), with cuticle thickness positively correlated (R 2 adjusted = 0.337) with increasing time-to-knockdown.

Middle-aged adults displayed a significant trend toward a lower degree of lip-line cant compared to younger adults ( p < 0.01).

Based on 24 cases only, a significant trend towards an increased number of patients with thyroiditis was observed among females (3.3% in 1993-1997 to 5.0% in 2008-2013, p < 0.01) ( Table 1 ).