“a significant trend”

Changes in the corticospinal tract We found a significant trend of change along the corticospinal tract only when we used the less stringent threshold of p < 0.005 (uncorrected for multiple comparisons).

Within the apoptotic pathway, Bim had borderline significance when compared to baseline at 24-hrs ( p = 0.03) and had a significant Trend Test ( p = 0.005), phospho-BAD (S112) was statically significant at 1-hr ( p = 0.009), at 5 h ( p = 0.005), and 24 h ( p < 0.001). phospho-BAD (S155) was also statically significant at 5 h ( p = 0.003) and 24-hrs ( p = 0.007) while phospho-FADD (S194) was borderline at 5 h ( p = 0.03) and significant at 24 h ( p = 0.001).

The method stated that although there was significant variability between tests, a significant trend was observed for Aniseikonia Inspector ( R = 0.63, R 2 = 0.40, p = 0.005) and New Aniseikonia Tests ( R = 0.54, R 2 = 0.29, p = 0.017), with subjective aniseikonia increasing as disparity increased.

In our study, only total lymphocytes showed a significant trend across the three categories, being highest in the favorable group and least in the adverse group ( p = 0.005).

We observed significantly higher lung asbestos body burden if any of these cell cycle genes were methylated ( P < 0.02), and there was a significant trend of increasing asbestos body counts as the number of methylated cell cycle pathway genes increased from 0 to 1 to >1 ( P < 0.005).

Of note, we observed a significant trend toward normalization of the B-cell compartment with significant increases in (i) the percentages of CD19 + CD27 + memory B-cells ( p = 0.005) and of non-class-switched memory B-cells ( p = 0.030) and (ii) class-switched memory B-cells (absolute count and percentage, p < 0.0001) in resolved cGVHD.

We found a significant trend of increasing SNIP values with milder types (JT = 743, P = 0.0053).

Only April showed a significant trend in BPH over the 10 years with a slope of 0.1540 per year ( P <0.0057).

Following these caveats, an analysis of the Dorado Outcrop basalt tag OTU library with clone libraries from other geographically-disparate studies reveals a significant trend of an increasing proportion of shared OTUs with sample set age ( p = 0.006; Figure 10 ).

There was a significant trend toward more concurrent infections over time (7.1% to 14.6%, P = 0.0060).

As shown in Table 1 , the characteristics that showed a significant trend across SOFA tertiles were mean blood pressure values ( P = 0.006), need of vasopressors for hemodynamic support ( P < 0.001), need for MV ( P < 0.001), the time from symptom onset to ICU admission ( P = 0.014), and treatment with tocilizumab ( P = 0.013).

Most owners (890/926, 96%) believed that obesity could cause risks to a dog’s health, but a significant trend existed ( P = 0.006) whereby more owners disagreed about the health risks as weight status increased from ideal weight (12/480, 2%), to overweight (14,317, 4%), to obese (10/129, 8%).

A random effect multinomial logit panel data model showed there was a significant trend over time ( p = 0.006 for the new onset of AF and VP and p = 0.01 for new BBB or IVCD) in the development of cardiac arrhythmias and ventricular conduction abnormalities ( Table 2 ).

These findings are consistent with those reported by Mersch et al., who observed a significant trend indicating an increased incidence of cervical cancer in BRCA2 carriers relative to the general population (p = 0.006) 22 .

The Genotype-Tissue Expression (GTEx) database showed a significant trend for increased HFE expression in rs9393682 C allele carriers ( P = 0.006; Figure 2A ). rs9393682 and rs1378033 fall within putative VDREs, and may alter 1,25-VD-mediated gene regulation.

Blood pressure values showed a significant trend towards a slight decrease at weeks 2 and 6 ( P = 0.006 and P = 0.003) followed by an incline towards initial levels at week 10 (Fig. 2 C and D).

Univariate analyses for CIMT progression as an ordinal (tertile) variable yielded a significant trend for increasing CIMT progression tertile with greater concentrations of fasting glucose ( P = 0.006) and a significant trend for less CIMT progression higher baseline CIMT ( P < 0.001).

However, the GLM analyses revealed a significant trend in relation to the seasonality for OTU 3194 ( cos (Month): F = 9.2, p = 0.006): it started increasing in spring to reach a maximum in summer, and to decrease again in autumn ( Figure 8 ). 4.

Procedural impact and perceived latency scores There was a significant trend for higher procedural impact and perceived latency scores across the three vascular beds with the increasing latencies ( p = 0.006 and p = 0.002, respectively) (Fig. 2 ).

At six weeks, a significant trend for haloperidol was observed on the PANSS positive score (18.2 ± 5.90 vs. 21.3 ± 2.51, p = 0.006).

Hazard ratios (95% confidence intervals) across increasing tertiles were 1.0 (reference), 1.44 (0.90–2.29), and 1.98 (1.21–3.25), with a significant trend ( p = 0.006).

Similarly, when examining the yearly occurrence of OPSCC in males, we found a significant trend for both p16 positive cases (Spearman r = 0.9286, p = 0.0067; linear regression R 2 = 0.8675, p = 0.0023) and p16 negative cases (Spearman r = 0.8469, p = 0.0238; linear regression R 2 = 0.7591, p = 0.01) (Fig. 1 C).

We observed a significant trend of increase in radical prostatectomies for treating prostate cancer over the years (p=0.007).

When analysing the duration until initial authorisation of a clinical trial application (CTA) over the last 10 years, it became obvious that there was a significant trend towards shorter approval times for non-integrated protocols ( r = − 0.76; p = 0.007, Fig. 4 a).

However, a significant trend was observed for certain cosmetic ingredients, such as pentylene glycol ( p = 0.007), retinol ( p = 0.052), and glycolic acid ( p = 0.062) (Table SIII ).