“a significant trend”

A significant trend to reduce the medians of the blood pressure values (SBP, -10 mm Hg in Group A and B; DBP – 4 mm Hg in Group A and 7 mm Hg in Group B, respectively), total cholesterol (Group A, 181 vs. 148 mg/dl and Group B, 189 vs160 mg/dl, respectively) and LDL cholesterol levels from 104 to 78 mg/dl (Group A) and from 107 to 81 mg/dl (Group B) were observed in both groups (all p < 0.05).

In model 1, when compared to the first quartile, the risk of hypertension was marginally lower in the second quartile (OR = 0.73, 95% CI: 0.63–0.86, P < .01) and the third quartile (OR = 0.74, 95% CI: 0.65–0.84, P < .01), with a significant trend ( P for trend = .02).

Of note, there was also a significant trend for DYNC1H1 and CR1 between the variant and nonvariant normal samples.

However, when the number of mammograms was considered as a continuous variable, under the assumption of linearity, we found a significant trend in BC risk (OR = 1.04; 95% CI: 1.01–1.06) with an increased risk of 4% by additional exposure.

Compounds that combine these two functions could represent a significant trend in oncology.

These four genes also exhibited a significant trend in the proportion of driver mutations since all nonsynonymous mutations were considered driver mutations (Tables 2(a) and 2(b) , ).

Linear regressions were performed on subjects’ full distribution (i.e., no binning) of reach angles and RTs after the critical RT bin, and a t- test was performed on the resulting slopes to test for the presence of a significant trend.

A significant trend of increased CK17 expression from normal oral mucosa to OL without dysplasia, OL with dysplasia, and OSCC was observed.

Moreover, a significant trend was observed toward increase in childhood obesity with the worsening of food insecurity (P dose–response = 0.007).

[ 38 ] found a significant trend in which contralateral BC was more likely to be detected by mammography surveillance in women who had their first BC diagnosed after 1994 relative to the earlier time period (P=0.005).

Results Context This study was conducted in the ICU of a tertiary care teaching hospital in Kerala, India, a state with a high proportion of medical professionals and a significant trend of nurse migration abroad.

We found a significant trend for increased ORs for below-reference sperm morphology with increasing Cu quartiles.

HC: There was a significant trend for PD cortical thinning in the following areas: in the right hemisphere, in the occipital superior area, in the cuneus and precuneus, in the superior orbito-frontal area, in the olfactory area and angular gyrus.

Both models included a continuous variable for the year of cohort inclusion, to test if there was a significant trend over time for the proportion of patients being persistent and adherent in the first year of treatment.

Although, as indicated by the reviewer, the difference in the average diffusion of MeCP2 R133C per cell is not statistically significant (Figure 3D), the distribution of diffusion coefficients is noticeably shifted and there is a significant trend toward higher diffusion coefficients (Figure 3C).

At the endpoint (42-month), only a significant trend in MPI score was observed, and a larger sample size is required to obtain robust results demonstrating the effect on MPI score.

The Cochran–Armitage trend test was used to determine whether a significant trend was present across the time period.

The caffeine content does not show a significant trend of increase or decrease with increasing storage time, which was due to the stable structure of the purine ring of caffeine [ 33 ]. 3.2.4.

A significant trend in the spread of the medfly northwards and upwards into areas that are less suitable for their establishment highlight the evolving invasive potential of the pest.

A significant trend of increase in the visual outcome improvement was observed from the first to the fifth PE therapy as compared with the visual outcome before the PE therapy (Friedman p < 0.001; Figure 2 ).

On the other hand, a significant trend was the more accelerated decrease in firmness during the organoleptic ripeness stage, reaching, in stage S6M, values that represented only 3.1% of the average value of stages S1D–S6D ( Figure 3 ), reflecting the rapid breakdown of cell wall components characteristic of this ripening phase [ 3 , 4 ]. 2.3.

Conclusion There was a significant trend between rubella seronegativity with age in young gravidae, but the pattern was opposite between gravidae born after versus in/before 1983, with the former having a higher incidence of seronegativity at all ages.

Research shows that from 1982 to 2014, 13.5% of the study areas in northern China showed a significant trend of earlier start dates of the growing season (SOS), and 23.1% of the study areas showed a significant trend of delayed end dates of the growing season (EOS) [ 33 ].

Low P-values are therefore indicative of a significant trend between increasing metformin dose and the event being analysed.

In the high-SDI regions, both sexes exhibited a significant trend in the incidence, mortality, and DALY rates of initially increasing, then decreasing, and subsequently increasing again over the 31 years ( Figure 1A–C ).