“a significant trend”

Nevertheless the past twenty years have seen a significant trend in the use of therapeutic antibodies for treating CNS diseases.

13 A significant trend of increase in receiving palliative care reduces the proportion of patients who die due to cancer.

Due to the increasing experience regarding the stability of screw osteosynthesis, there has been a significant trend toward fixation-free early functional treatment.

A significant trend across GV quartiles was observed ( p for trend < 0.01), although excess risk was primarily driven by the highest quartile.

We also note that while fermented soy foods showed a significant trend, individual components of natto did not appear to contribute.

As the impact loading increases, the degree of damage gradually increases, but the peak stress and strain rates do not show a significant trend.

Although the great majority of these women was lean (median BMI of 22.3 kg/m 2 ; 20.3–24.8 interquartile range), BMI data showed a significant trend to higher values from the north to the south of Italy, while no significant difference was observed between mothers residing in rural or urban areas. 2.2.

A significant trend in anti-cancer drug development is the search for therapeutic compounds that are not substrates of drug efflux transporters.

Longer daily time and total duration of SHS exposure at baseline showed a significant trend for the risk of new-onset hypertension, whereas the relationships between daily time, weekly frequency, and total duration of SHS exposure at follow-up and the risk of new-onset hypertension were stronger and more obvious (all p for trends < 0.001) ( Table 3 ).

In both districts of Morogoro, there was a significant trend of higher drug uptake rates among those who had completed primary school than among those who had not, but such trend was not seen in the two Lindi districts.

Furthermore, a significant trend of increasing risk of developing hypertension was observed with escalating SUA trajectories in all three models ( P for trend < 0.01). 3.4.

IRR analysis showed that the effect of surgery diminished with age (≥20 years), with a significant trend observed only for depression in men.

Considering the various functional benefits of LAB present in fermented foods, the production of probiotic fermented foods is a significant trend in the worldwide fermented foods business [ 11 ].

With a significant trend for increasing Ct.Ar and Ct.Th from NW to OB status, our results are generally in agreement with existing literature indicating that OB women had higher Ct.Ar and Ct.Th values.

A significant trend of downregulation of piRNA clusters was also observed in the comparison of groups Low1-High1, and High2-High1.

White males were underrepresented in pediatrics and OB/GYN with a significant trend toward greater underrepresentation.

The rapid evolution of technological products, particularly Telehealth solutions, during the COVID-19 pandemic, underscores a significant trend in healthcare delivery [ 62 ].

Considering both of these results, if individuals with diabetes had not been excluded from the study, it may be possible that a significant trend between duration of night work and prevalence of IFG would have been identified in those with only abdominal obesity, only overall obesity, or with both simultaneously.

There was a significant trend toward higher ORs for ischemic stroke per 1 SD–higher carotid measures at younger ages and lower SBP levels (eg, the OR for ischemic stroke with plaque burden varied from 1.23; 95% CI, 1.11-1.37 at ages 70-89 years to 1.52; 95% CI, 1.32-1.76 at ages 40-39 years, P = .02 for trend, and from 1.20; 95% CI, 1.10-1.31 at SBP ≥140 mm Hg to 1.44; 95% CI, 1.23-1.69 at SBP <120 mm Hg, P = .02 for trend) (eFigure 3 in the Supplement ).

Further, possible correlations with subthreshold manic-hypomanic comorbidity are suggested among males, showing a significant trend particularly for lifetime trauma exposure and for the newly introduced maladaptive behaviors.

Consistent with previous studies, our patients in the high arterial stiffness group showed significantly higher serum OPG levels that, after being categorized into tertiles, demonstrated a significant trend with central arterial stiffness after complete adjustment of potential confounding factors, analyzed as either continuous or dichotomous outcome variable.

Although we did not observe a significant difference in in‐hospital mortality across the SES quartiles in the overall cohort (P‐trend=0.22), there was a significant trend toward reduced in‐hospital mortality across the SES quartiles in younger patients (<75 years) (P‐trend<0.001).

Meanwhile, for a few trait-related pathways, when the P -value reached a significant trend, this study was also reserved for subsequent analysis.

The mean length of stay of these hospitalizations was 8.9 days (SE, 0.06), and there was a significant trend towards increased length of stay over time ( P trend <0.001; Figure S3 : trends in mean length of stay over time).

Our findings indicate that when HbA1c is treated as a categorical variable, there is a significant trend towards increased risk of poor functional outcome at 3 months with rising HbA1c levels.